Can we teach an old drug new tricks?

Trends in Parasitology

Volumn 28, Issue 6, 2012, Pages 220-224

  Ch'ng, Jun Hong ^a   Renia, Laurent ^b   Nosten, Francois ^c,d   Tan, Kevin S W ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^d Center for Clinical Vaccinology and Tropical Medicine   (United Kingdom)

Author keywords

Apoptosis; Chloroquine; Digestive vacuole; Dosage; Dose escalation; Drug resistance; High dose; Lysosomotropic; Malaria; Plasmodium falciparum; Programmed cell death; Regimen

Indexed keywords

CHLOROQUINE;

APOPTOSIS; CONTINUOUS INFUSION; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG MECHANISM; HUMAN; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; REVIEW; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 84861531462     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2012.02.005     Document Type: Review

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