Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Meslin, Benoît ^a   Beavogui, Abdoul H ^a,c   Fasel, Nicolas ^b   Picot, Stéphane ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c Centre de Formation et de Recherche en Santé Rurale de Maferinyah   (Guinea)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE SPECIFIC PROTEASE; ARTEMISIN DERIVATIVE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CALPAIN; CHLOROQUINE; METACASPASE; METACASPASE 1; PROTEINASE; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; ARGININE PROTEASE; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CALCIUM; CASPASE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; HYDROGEN PEROXIDE; MCA 1 PROTEIN, PLASMODIUM FALCIPARUM; MCA-1 PROTEIN, PLASMODIUM FALCIPARUM; OXIDIZING AGENT; PEPTIDE CHLOROMETHYL KETONE;

ANTIBIOTIC SENSITIVITY; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; IC 50; LEISHMANIA MAJOR; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PARASITE; PLASMODIUM FALCIPARUM; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; APOPTOSIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FLOW CYTOMETRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS;

LEISHMANIA MAJOR; PLASMODIUM FALCIPARUM; PROTOZOA; SACCHAROMYCES;

AMINO ACID CHLOROMETHYL KETONES; ANTIMALARIALS; APOPTOSIS; BASE SEQUENCE; CALCIUM; CASPASES; CHLOROQUINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPEPTIDASES; FLOW CYTOMETRY; HYDROGEN PEROXIDE; MOLECULAR SEQUENCE DATA; OXIDANTS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 80051714542     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023867     Document Type: Article

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