Central role of SREBP-2 in the pathogenesis of osteoarthritis

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Kostopoulou, Fotini ^a,b   Gkretsi, Vasiliki ^b   Malizos, Konstantinos N ^a,b   Iliopoulos, Dimitrios ^c   Oikonomou, Pagona ^b   Poultsides, Lazaros ^a   Tsezou, Aspasia ^a,b  

^a UNIVERSITY OF THESSALY   (Greece)

^b INSTITUTE OF HUMAN PERFORMANCE AND REHABILITATION   (Greece)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; ARGINYLGLYCYLASPARTIC ACID; CD51 ANTIGEN; COLLAGENASE 3; CYTOSINE; GUANINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INTERLEUKIN 1BETA; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMAD3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ARTICLE; CARTILAGE CELL; COHORT ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE TARGETING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSFECTION; GREECE; HUMAN; HUMAN CELL; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; AGGRECANS; ALLELES; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE I; COLLAGEN TYPE II; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; HUMANS; HYDROXYCHOLESTEROLS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; INTEGRIN ALPHAV; MALE; MIDDLE AGED; OLIGOPEPTIDES; OSTEOARTHRITIS; PEPTIDES, CYCLIC; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SMAD3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSFORMING GROWTH FACTOR BETA;

EID: 84861473650     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035753     Document Type: Article

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