The in vitro and in vivo study on Self-Nanoemulsifying Drug Delivery System (SNEDDS) based on insulin-phospholipid complex

Journal of Biomedical Nanotechnology

Volumn 8, Issue 1, 2012, Pages 90-97

  Zhang, Qianyu ^a   He, Na ^a   Zhang, Li ^a   Zhu, Feng ^a   Chen, Qiuxia ^a   Qin, Yao ^a   Zhang, Zhirong ^a   Zhang, Qiang ^c   Wang, Shuang ^b   He, Qin ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Diabetic models; Enhanced oral absorption; Insulin Phospholipid Complex (IPC); MDCK monolayer; Self Nanoemulsifying Drug Delivery Systems (SNEDDS)

Indexed keywords

DRUG DELIVERY SYSTEM; DRUG VEHICLES; HYPOGLYCEMIC EFFECT; IN-VITRO; INSULIN-PHOSPHOLIPID COMPLEX (IPC); MDCK CELLS; OIL PHASE; ORAL ABSORPTION; ORAL ADMINISTRATION; ORAL DELIVERY; WISTAR RAT;

DRUG DELIVERY; MONOLAYERS; PHOSPHOLIPIDS;

INSULIN;

INSULIN; OIL; PHOSPHOLIPID; SOLVENT;

ARTICLE; DIABETES MELLITUS; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EVAPORATION; HYPOGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; MONOLAYER CULTURE; NANOEMULSION; NONHUMAN; RAT; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; SOLVENT EXTRACTION;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DOGS; DRUG CARRIERS; EMULSIONS; INSULIN; MALE; NANOSTRUCTURES; NANOTECHNOLOGY; PARTICLE SIZE; PHOSPHOLIPIDS; RATS; RATS, WISTAR; SOLUBILITY; SWINE;

EID: 84861469900     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1371     Document Type: Article

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