Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice

International Journal for Parasitology: Drugs and Drug Resistance

Volumn 2, Issue , 2012, Pages 109-120

  Schorer, Michelle ^a   Debache, Karim ^a   Barna, Fabienne ^a   Monney, Thierry ^a   Müller, Joachim ^a   Boykin, David W ^b   Stephens, Chad E ^c   Hemphill, Andrew ^a  

^a VETSUISSE FACULTY UNIVERSITY OF ZURICH   (Switzerland)

^b GEORGIA STATE UNIVERSITY   (United States)

^c AUGUSTA STATE UNIVERSITY   (United States)

Author keywords

Arylimidamides; In vivo activity; Invasion; Membrane integrity; Neospora caninum; Nucleolus; Proliferation; Tachyzoites

Indexed keywords

ANTIPARASITIC AGENT; DB 745; DB 750; PENTAMIDINE DERIVATIVE; PLACEBO; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CELL MEMBRANE; CONTROLLED STUDY; FEMALE; IC 50; MOUSE; NEOSPORA CANINUM; NEOSPOROSIS; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; TACHYZOITE; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84861467332     PISSN: 22113207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpddr.2012.03.001     Document Type: Article

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