In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 6, 2011, Pages 1295-1297

  da Silva, Cristiane França ^a   Junqueira, Angela ^a   Lima, Marli Maria ^a   Romanha, Alvaro José ^a   Sales Junior, Policarpo Ademar ^a   Stephens, Chad E ^b   Som, Phanneth ^c   Boykin, David W ^c   de Nazaré Correia Soeiro, Maria ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b AUGUSTA STATE UNIVERSITY   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Chagas' disease; Chemotherapy; T. cruzi

Indexed keywords

ANTITRYPANOSOMAL AGENT; BENZNIDAZOLE; CRYSTAL VIOLET; DB 667; DB 709; DB 745B; DB 749; DB 946; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG EFFICACY; HEART MUSCLE CELL; IC 50; IN VITRO STUDY; MICROSCOPY; MOUSE; NONHUMAN; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

AMIDINES; ANIMALS; ANTIPROTOZOAL AGENTS; CELL SURVIVAL; CELLS, CULTURED; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICROSCOPY; MYOCYTES, CARDIAC; PARASITIC SENSITIVITY TESTS; TETRAZOLIUM SALTS; THIAZOLES; TRYPANOSOMA CRUZI;

EID: 79956028472     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr140     Document Type: Article

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