Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 8, 2012, Pages 1214-1222

  Lim, Min Jin ^a   Ahn, Ji Yeon ^a   Han, Youngsoo ^b   Yu, Chi Ho ^a   Kim, Mi Hyoung ^a   Lee, Sae Lo Oom ^a   Lim, Dae Seog ^c   Song, Jie Young ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c CHA University   (South Korea)

Author keywords

Acriflavine; ER stress; p53; Radiosensitivity

Indexed keywords

ACRIFLAVINE; CASPASE 12; CASPASE 2; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN; CYTOCHROME C; ENDONUCLEASE; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING TRANSMEMBRANSE KINASE AND ENDONUCLEASE 1ALPHA; LUCIFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CLONOGENIC ASSAY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; FEMALE; GAMMA IRRADIATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; REPORTER GENE; TUMOR VOLUME;

ACRIFLAVINE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CHEMORADIOTHERAPY; COLONIC NEOPLASMS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; FEMALE; GAMMA RAYS; HCT116 CELLS; HT29 CELLS; HUMANS; MICE; MICE, NUDE; MITOCHONDRIA; MOLECULAR STRUCTURE; PHOSPHORYLATION; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EUKARYOTA; MUS;

EID: 84861452422     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.04.022     Document Type: Article

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