메뉴 건너뛰기




Volumn 81, Issue 6, 2012, Pages 770-777

Nonequilibrium activation of a G-protein-coupled receptor

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; NORADRENALIN;

EID: 84861423107     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.077693     Document Type: Article
Times cited : (11)

References (41)
  • 2
    • 0027530780 scopus 로고
    • 2-autoreceptors: Agonist dissociation constants and recovery after irreversible inactivation
    • Agneter E, Drobny H, and Singer EA (1993) Central α2-autoreceptors: agonist dissociation constants and recovery after irreversible inactivation. Br J Pharmacol 108:370-375. (Pubitemid 23032541)
    • (1993) British Journal of Pharmacology , vol.108 , Issue.2 , pp. 370-375
    • Agneter, E.1    Drobny, H.2    Singer, E.A.3
  • 3
    • 0030963999 scopus 로고    scopus 로고
    • The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors
    • DOI 10.1007/PL00005052
    • Agneter E, Singer EA, Sauermann W, and Feuerstein TJ (1997) The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors. Naunyn Schmiedebergs Arch Pharmacol 356:283-292. (Pubitemid 27376457)
    • (1997) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.356 , Issue.3 , pp. 283-292
    • Agneter, E.1    Singer, E.A.2    Sauermann, W.3    Feuerstein, T.J.4
  • 4
    • 0001591369 scopus 로고
    • Receptor reserve and threshold phenomena. I. Theory and experiments with autonomic drugs tested on isolated organs
    • Ariens EJ, van Rossum J, and Koopman PC (1960) Receptor reserve and threshold phenomena. I. Theory and experiments with autonomic drugs tested on isolated organs. Arch Int Pharmacodyn Ther 127:459-478.
    • (1960) Arch Int Pharmacodyn Ther , vol.127 , pp. 459-478
    • Ariens, E.J.1    Van Rossum, J.2    Koopman, P.C.3
  • 5
    • 0023279479 scopus 로고
    • Some implications of the high intrasynaptic norepinephrine concentrations in resistance arteries
    • Bevan JA, Laher I, and Rowan R (1987) Some implications of the high intrasynaptic norepinephrine concentrations in resistance arteries. Blood Vessels 24:137-140. (Pubitemid 17096541)
    • (1987) Blood Vessels , vol.24 , Issue.3 , pp. 137-140
    • Bevan, J.A.1    Laher, I.2    Rowan, R.3
  • 6
    • 0021345217 scopus 로고
    • Presynaptic alpha-receptor control of adrenergic transmitter release in blood vessels
    • Bevan JA, Tayo FM, Rowan RA, and Bevan RD (1984) Presynaptic alpha-receptor control of adrenergic transmitter release in blood vessels. Fed Proc 43:1365-1370. (Pubitemid 14173502)
    • (1984) Federation Proceedings , vol.43 , Issue.5 , pp. 1365-1370
    • Bevan, J.A.1    Tayo, F.M.2    Rowan, R.A.3    Bevan, R.D.4
  • 7
    • 0021990306 scopus 로고
    • An operational model of pharmacological agonism: The effect of E/[A] curve shape on agonist dissociation constant estimation
    • Black JW, Leff P, Shankley NP, and Wood J (1985) An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation. Br J Pharmacol 84:561-571. (Pubitemid 15169246)
    • (1985) British Journal of Pharmacology , vol.84 , Issue.2 , pp. 561-571
    • Black, J.W.1    Leff, P.2    Shankley, N.P.3
  • 11
    • 34249741955 scopus 로고    scopus 로고
    • What have we learned from single ion channels?
    • Colquhoun D (2007) What have we learned from single ion channels? J Physiol 581:425-427.
    • (2007) J Physiol , vol.581 , pp. 425-427
    • Colquhoun, D.1
  • 14
    • 33748932547 scopus 로고    scopus 로고
    • Adrenoceptors and signal transduction in neurons
    • Hein L (2006) Adrenoceptors and signal transduction in neurons. Cell Tissue Res 326:541-551.
    • (2006) Cell Tissue Res , vol.326 , pp. 541-551
    • Hein, L.1
  • 15
    • 28644443374 scopus 로고    scopus 로고
    • Dynamics of receptor/G protein coupling in living cells
    • DOI 10.1038/sj.emboj.7600870
    • Hein P, Frank M, Hoffmann C, Lohse MJ, and Bünemann M (2005) Dynamics of receptor/G protein coupling in living cells. EMBO J 24:4106-4114. (Pubitemid 41752879)
    • (2005) EMBO Journal , vol.24 , Issue.23 , pp. 4106-4114
    • Hein, P.1    Frank, M.2    Hoffmann, C.3    Lohse, M.J.4    Bunemann, M.5
  • 19
    • 78049403279 scopus 로고    scopus 로고
    • Ligand binding assays at equilibrium: Validation and interpretation
    • Hulme EC and Trevethick MA (2010) Ligand binding assays at equilibrium: validation and interpretation. Br J Pharmacol 161:1219-1237.
    • (2010) Br J Pharmacol , vol.161 , pp. 1219-1237
    • Hulme, E.C.1    Trevethick, M.A.2
  • 21
    • 0036463901 scopus 로고    scopus 로고
    • Efficacy at G-protein-coupled receptors
    • Kenakin T (2002) Efficacy at G-protein-coupled receptors. Nat Rev Drug Discov 1:103-110.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 103-110
    • Kenakin, T.1
  • 22
    • 0033771402 scopus 로고    scopus 로고
    • The superfamily of heptahelical receptors
    • Lefkowitz RJ (2000) The superfamily of heptahelical receptors. Nat Cell Biol 2:E133-E136.
    • (2000) Nat Cell Biol , vol.2
    • Lefkowitz, R.J.1
  • 23
    • 0021954010 scopus 로고
    • 2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet. Evidence for a receptor reserve
    • Lenox RH, Ellis J, Van Riper D, and Ehrlich YH (1985) Alpha 2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet: evidence for a receptor reserve. Mol Pharmacol 27:1-9. (Pubitemid 15162378)
    • (1985) Molecular Pharmacology , vol.27 , Issue.1 , pp. 1-9
    • Lenox, R.H.1    Ellis, J.2    Van Riper, D.3    Ehrlich, Y.H.4
  • 26
    • 77950588803 scopus 로고    scopus 로고
    • A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation
    • Maier-Peuschel M, Frölich N, Dees C, Hommers LG, Hoffmann C, Nikolaev VO, and Lohse MJ (2010) A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation. J Biol Chem 285:8793-8800.
    • (2010) J Biol Chem , vol.285 , pp. 8793-8800
    • Maier-Peuschel, M.1    Frölich, N.2    Dees, C.3    Hommers, L.G.4    Hoffmann, C.5    Nikolaev, V.O.6    Lohse, M.J.7
  • 27
    • 0019723535 scopus 로고
    • Quantitative analysis of drug-receptor interactions: II. Determination of the properties of receptor subtypes
    • DOI 10.1016/0024-3205(81)90208-3
    • Molinoff PB, Wolfe BB, and Weiland GA (1981) Quantitative analysis of drug-receptor interactions: II. Determination of the properties of receptor subtypes. Life Sci 29:427-443. (Pubitemid 11005430)
    • (1981) Life Sciences , vol.29 , Issue.5 , pp. 427-443
    • Molinoff, P.B.1    Wolfe, B.B.2    Weiland, G.A.3
  • 28
    • 0001708862 scopus 로고
    • Receptor occupancy and tissue response
    • Nickerson M (1956) Receptor occupancy and tissue response. Nature 178:697-698.
    • (1956) Nature , vol.178 , pp. 697-698
    • Nickerson, M.1
  • 30
    • 71249091373 scopus 로고    scopus 로고
    • In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus
    • Park J, Kile BM, and Wightman RM (2009) In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus. Eur J Neurosci 30:2121-2133.
    • (2009) Eur J Neurosci , vol.30 , pp. 2121-2133
    • Park, J.1    Kile, B.M.2    Wightman, R.M.3
  • 31
    • 81255135822 scopus 로고    scopus 로고
    • In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry
    • Park J, Takmakov P, and Wightman RM (2011) In vivo comparison of norepinephrine and dopamine release in rat brain by simultaneous measurements with fast-scan cyclic voltammetry. J Neurochem 119:932-944.
    • (2011) J Neurochem , vol.119 , pp. 932-944
    • Park, J.1    Takmakov, P.2    Wightman, R.M.3
  • 32
    • 0346687568 scopus 로고    scopus 로고
    • Adrenergic receptor knockout mice: Distinct functions of 9 receptor subtypes
    • DOI 10.1016/j.pharmthera.2003.10.004
    • Philipp M and Hein L (2004) Adrenergic receptor knockout mice: distinct functions of 9 receptor subtypes. Pharmacol Ther 101:65-74. (Pubitemid 38068526)
    • (2004) Pharmacology and Therapeutics , vol.101 , Issue.1 , pp. 65-74
    • Philipp, M.1    Hein, L.2
  • 33
    • 0001893475 scopus 로고
    • Transport and storage of catecholamines in vesicles
    • Philippu A and Matthaei H (1988) Transport and storage of catecholamines in vesicles. Handb Exp Pharmacol 90:1-42.
    • (1988) Handb Exp Pharmacol , vol.90 , pp. 1-42
    • Philippu, A.1    Matthaei, H.2
  • 35
    • 0022446338 scopus 로고
    • Spare α adrenoceptors in the peripheral circulation: Excitationcontraction coupling
    • Ruffolo RR Jr (1986) Spare α adrenoceptors in the peripheral circulation: excitationcontraction coupling. Fed Proc 45:2341-2346.
    • (1986) Fed Proc , vol.45 , pp. 2341-2346
    • Ruffolo Jr., R.R.1
  • 36
    • 0028307762 scopus 로고
    • 2- adrenoceptors of rat vas deferens using operational and null approaches
    • 2-adrenoceptors of rat vas deferens using operational and null approaches. Eur J Pharmacol 258:229-238.
    • (1994) Eur J Pharmacol , vol.258 , pp. 229-238
    • Sallés, J.1    Giraldo, J.2    Badia, A.3
  • 37
    • 0023110942 scopus 로고
    • Shallow agonist competition binding curves for β-adrenergic receptors: The role of tight agonist binding
    • Severne Y, Ijzerman A, Nerme V, Timmerman H, and Vauquelin G (1987) Shallow agonist competition binding curves for β-adrenergic receptors: the role of tight agonist binding. Mol Pharmacol 31:69-73. (Pubitemid 17016419)
    • (1987) Molecular Pharmacology , vol.31 , Issue.1 , pp. 69-73
    • Severne, Y.1    IJzerman, A.2    Nerme, V.3
  • 38
    • 0038729670 scopus 로고    scopus 로고
    • Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
    • DOI 10.1038/nbt838
    • Vilardaga JP, Bünemann M, Krasel C, Castro M, and Lohse MJ (2003) Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nat Biotechnol 21:807-812. (Pubitemid 36791401)
    • (2003) Nature Biotechnology , vol.21 , Issue.7 , pp. 807-812
    • Vilardaga, J.-P.1    Bunemann, M.2    Krasell, C.3    Castro, M.4    Lohse, M.J.5
  • 39
    • 29444444012 scopus 로고    scopus 로고
    • Molecular basis of inverse agonism in a G protein-coupled receptor
    • Vilardaga JP, Steinmeyer R, Harms GS, and Lohse MJ (2005) Molecular basis of inverse agonism in a G protein-coupled receptor. Nat Chem Biol 1:25-28.
    • (2005) Nat Chem Biol , vol.1 , pp. 25-28
    • Vilardaga, J.P.1    Steinmeyer, R.2    Harms, G.S.3    Lohse, M.J.4
  • 40
    • 0019823390 scopus 로고
    • Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties
    • Weiland GA and Molinoff PB (1981) Quantitative analysis of drug-receptor interactions. I. Determination of kinetic and equilibrium properties. Life Sci 29:313-330. (Pubitemid 12224162)
    • (1981) Life Sciences , vol.29 , Issue.4 , pp. 313-330
    • Weiland, G.A.1    Molinoff, P.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.