-
1
-
-
0003964363
-
-
American Cancer Society American Cancer Society GA USA
-
American Cancer Society. Cancer Facts Figures. American Cancer Society, GA, USA, 9 (2009
-
(2009)
Cancer Facts Figures
, vol.9
-
-
-
2
-
-
62549106985
-
ER re-expression and re-sensitization to endocrine therapies in ER-negative breast cancers
-
Brinkman JA, El-Ashry D. ER re-expression and re-sensitization to endocrine therapies in ER-negative breast cancers. J. Mammary Gland Biol. Neoplasia 14(1), 67-78 (2009
-
(2009)
J. Mammary Gland Biol. Neoplasia
, vol.14
, Issue.1
, pp. 67-78
-
-
Brinkman, J.A.1
El-Ashry, D.2
-
3
-
-
63449113187
-
Epigenetic alterations in the breast: Implications for breast cancer detection prognosis and treatment
-
Dworkin AM, Huang TH, Toland AE. Epigenetic alterations in the breast: implications for breast cancer detection, prognosis and treatment. Semin. Cancer Biol. 19(3), 165-171 (2009
-
(2009)
Semin. Cancer Biol.
, vol.19
, Issue.3
, pp. 165-171
-
-
Dworkin, A.M.1
Huang, T.H.2
Toland, A.E.3
-
4
-
-
33745102306
-
Estrogen receptors: Role in breast cancer
-
Duffy MJ. Estrogen receptors: role in breast cancer. Crit. Rev. Clin. Lab. Sci. 43(4), 325-347 (2006
-
(2006)
Crit. Rev. Clin. Lab. Sci.
, vol.43
, Issue.4
, pp. 325-347
-
-
Duffy, M.J.1
-
5
-
-
26044441358
-
Breast cancer risk factors according to joint estrogen receptor and progesterone receptor status
-
Rusiecki JA, Holford TR, Zahm SH, Zheng T. Breast cancer risk factors according to joint estrogen receptor and progesterone receptor status. Cancer Detect Prev. 29(5), 419-426 (2005
-
(2005)
Cancer Detect. Prev.
, vol.29
, Issue.5
, pp. 419-426
-
-
Rusiecki, J.A.1
Holford, T.R.2
Zahm, S.H.3
Zheng, T.4
-
6
-
-
78649923835
-
Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status
-
Li Q, Eklund AC, Juul N et al. Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status. PLoS One 5(12), e15031 (2010
-
(2010)
PLoS One
, vol.5
, Issue.12
-
-
Li, Q.1
Eklund, A.C.2
Juul, N.3
-
7
-
-
77954526150
-
American society of clinical oncology college of american pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
-
Hammond ME, Hayes DF, Dowsett M et al. American Society of Clinical oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J. Clin. Oncol. 28(16), 2784-2795 (2010
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.16
, pp. 2784-2795
-
-
Hammond, M.E.1
Hayes, D.F.2
Dowsett, M.3
-
8
-
-
78651511053
-
Epigenetic reactivation of estrogen receptor: Promising tools for restoring response to endocrine therapy
-
Saxena NK, Sharma D. Epigenetic reactivation of estrogen receptor: promising tools for restoring response to endocrine therapy. Mol. Cell. Pharmacol. 2(5), 191-202 (2010
-
(2010)
Mol. Cell. Pharmacol.
, vol.2
, Issue.5
, pp. 191-202
-
-
Saxena, N.K.1
Sharma, D.2
-
9
-
-
64349095390
-
An operational definition of epigenetics
-
Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes Dev. 23(7), 781-783 (2009
-
(2009)
Genes Dev.
, vol.23
, Issue.7
, pp. 781-783
-
-
Berger, S.L.1
Kouzarides, T.2
Shiekhattar, R.3
Shilatifard, A.4
-
10
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N. Engl. J. Med. 358(11), 1148-1159 (2008
-
(2008)
N. Engl. J. Med.
, vol.358
, Issue.11
, pp. 1148-1159
-
-
Esteller, M.1
-
11
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat. Med. 17(3), 330-339 (2011
-
(2011)
Nat. Med.
, vol.17
, Issue.3
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
12
-
-
51349111360
-
Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer
-
Davoren PA, McNeill RE, Lowery AJ, Kerin MJ, Miller N. Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer. BMC Mol. Biol. 9, 76 (2008
-
(2008)
BMC Mol. Biol.
, vol.9
, pp. 76
-
-
Davoren, P.A.1
McNeill, R.E.2
Lowery, A.J.3
Kerin, M.J.4
Miller, N.5
-
13
-
-
38149042783
-
Programmed cell death 4 PDCD4 is an important functional target of the microRNA miR-21 in breast cancer cells
-
Frankel LB, Christoffersen NR, Jacobsen A et al. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 283(2), 1026-1033 (2008
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.2
, pp. 1026-1033
-
-
Frankel, L.B.1
Christoffersen, N.R.2
Jacobsen, A.3
-
14
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65(16), 7065-7070 (2005
-
(2005)
Cancer Res.
, vol.65
, Issue.16
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
-
15
-
-
34247495591
-
Mir-21-mediated tumor growth
-
Si ML, Zhu S, Wu H et al. miR-21- mediated tumor growth. Oncogene 26(19), 2799-2803 (2007
-
(2007)
Oncogene
, vol.26
, Issue.19
, pp. 2799-2803
-
-
Si, M.L.1
Zhu, S.2
Wu, H.3
-
16
-
-
55749101607
-
Estrogen receptor and HER2 n status affect epigenetic differences of tumor-related genes in primary breast tumors
-
Sunami E, Shinozaki M, Sim MS et al. Estrogen receptor and HER2/n status affect epigenetic differences of tumor-related genes in primary breast tumors. Breast Cancer Res. 10(3), R46 (2008
-
(2008)
Breast Cancer Res.
, vol.10
, Issue.3
-
-
Sunami, E.1
Shinozaki, M.2
Sim, M.S.3
-
17
-
-
84856236200
-
Primary tumor classification according to methylation pattern is prognostic in patients with early stage ER-negative breast cancer
-
van Hoesel AQ, van de Velde CJ, Kuppen PJ et al. Primary tumor classification according to methylation pattern is prognostic in patients with early stage ER-negative breast cancer. Breast Cancer Res. Treat. 131(3), 859-869 (2012
-
(2012)
Breast Cancer Res. Treat.
, vol.131
, Issue.3
, pp. 859-869
-
-
Van Hoesel, A.Q.1
Van De Velde, C.J.2
Kuppen, P.J.3
-
18
-
-
77954661329
-
Aberrant DNA methylation in malignant melanoma
-
Schinke C, Mo Y, Yu Y et al. Aberrant DNA methylation in malignant melanoma. Melanoma Res. 20(4), 253-265 (2010
-
(2010)
Melanoma Res.
, vol.20
, Issue.4
, pp. 253-265
-
-
Schinke, C.1
Mo, Y.2
Yu, Y.3
-
19
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 128(4), 683-692 (2007
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
20
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela A, Esteller M. Epigenetic modifications and human disease. J. Nat. Biotechnol. 28(10), 1057-1068 (2010
-
(2010)
J. Nat. Biotechnol.
, vol.28
, Issue.10
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
22
-
-
79952111066
-
Chromatin remodeling in mammary gland differentiation and breast tumorigenesis
-
Huang TH, Esteller M. Chromatin remodeling in mammary gland differentiation and breast tumorigenesis. Cold Spring Harb. Perspect. Biol. 2(9), A004515 (2010
-
(2010)
Cold Spring Harb. Perspect. Biol.
, vol.2
, Issue.9
-
-
Huang, T.H.1
Esteller, M.2
-
23
-
-
77953873130
-
The epigenetics of breast cancer
-
Jovanovic J, Ronneberg JA, Tost J, Kristensen V. The epigenetics of breast cancer. Mol. Oncol. 4(3), 242-254 (2010
-
(2010)
Mol. Oncol.
, vol.4
, Issue.3
, pp. 242-254
-
-
Jovanovic, J.1
Ronneberg, J.A.2
Tost, J.3
Kristensen, V.4
-
24
-
-
61549112191
-
Epigenomics and breast cancer
-
Lo PK, Sukumar S. Epigenomics and breast cancer. Pharmacogenomics 9(12), 1879-1902 (2008
-
(2008)
Pharmacogenomics
, vol.9
, Issue.12
, pp. 1879-1902
-
-
Lo, P.K.1
Sukumar, S.2
-
25
-
-
77149122714
-
Epigenetic regulation in estrogen receptor positive breast cancer-role in treatment response
-
Pathiraja TN, Stearns V, Oesterreich S. Epigenetic regulation in estrogen receptor positive breast cancer-role in treatment response. J. Mammary Gland Biol. Neoplasia 15(1), 35-47 (2010
-
(2010)
J. Mammary Gland Biol. Neoplasia
, vol.15
, Issue.1
, pp. 35-47
-
-
Pathiraja, T.N.1
Stearns, V.2
Oesterreich, S.3
-
26
-
-
16844383767
-
Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis
-
Shinozaki M, Hoon DS, Giuliano AE et al. Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis. Clin. Cancer Res. 11(6), 2156-2162 (2005
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.6
, pp. 2156-2162
-
-
Shinozaki, M.1
Hoon, D.S.2
Giuliano, A.E.3
-
27
-
-
76749116065
-
CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients
-
Sharma G, Mirza S, Parshad R et al. CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients. Clin. Biochem. 43(4-5), 373-379 (2010
-
(2010)
Clin. Biochem.
, vol.43
, Issue.4-5
, pp. 373-379
-
-
Sharma, G.1
Mirza, S.2
Parshad, R.3
-
28
-
-
52249111637
-
Quantification of LINE1 in circulating DNA as a molecular biomarker of breast cancer
-
Sunami E, Vu AT, Nguyen SL, Giuliano AE, Hoon DS. Quantification of LINE1 in circulating DNA as a molecular biomarker of breast cancer. Ann. N. Y. Acad. Sci. 1137, 171-174 (2008
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1137
, pp. 171-174
-
-
Sunami, E.1
Vu, A.T.2
Nguyen, S.L.3
Giuliano, A.E.4
Hoon, D.S.5
-
29
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science 293(5532), 1074-1080 (2001
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
30
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 128(4), 693-705 (2007
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
31
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in polycomb-group silencing
-
Cao R, Wang L, Wang H et al. Role of histone H3 lysine 27 methylation in polycomb-group silencing. Science 298(5595), 1039-1043 (2002
-
(2002)
Science
, vol.298
, Issue.5595
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
-
32
-
-
0037111831
-
Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of zeste protein
-
Kuzmichev A, Nishioka K, Erdjument- Bromage H, Tempst P, Reinberg D. Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein. Genes Dev. 16(22), 2893-2905 (2002
-
(2002)
Genes Dev.
, vol.16
, Issue.22
, pp. 2893-2905
-
-
Kuzmichev, A.1
Nishioka, K.2
Erdjument-Bromage, H.3
Tempst, P.4
Reinberg, D.5
-
33
-
-
32844459336
-
The polycomb group protein EZH2 directly controls DNA methylation
-
Vire E, Brenner C, Deplus R et al. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439(7078), 871-874 (2006
-
(2006)
Nature
, vol.439
, Issue.7078
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
-
34
-
-
28044455435
-
Micro primer: The biogenesis and function of microRNA
-
Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development 132(21), 4645-4652 (2005
-
(2005)
Development
, vol.132
, Issue.21
, pp. 4645-4652
-
-
Du, T.1
Zamore, P.D.2
-
35
-
-
79960040020
-
Micro RNA in cancer-the involvement of aberrant microRNA biogenesis regulatory pathways
-
Davis BN, Hata A. microRNA in cancer - the involvement of aberrant microRNA biogenesis regulatory pathways. Genes Cancer 1(11), 1100-1114 (2010
-
(2010)
Genes Cancer
, vol.1
, Issue.11
, pp. 1100-1114
-
-
Davis, B.N.1
Hata, A.2
-
36
-
-
33747876113
-
Micro RNA-cancer connection: The beginning of a new tale
-
Calin GA, Croce CM. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res. 66(15), 7390-7394 (2006
-
(2006)
Cancer Res.
, vol.66
, Issue.15
, pp. 7390-7394
-
-
Calin, G.A.1
Croce, C.M.2
-
37
-
-
78650977713
-
Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer
-
Asaga S, Kuo C, Nguyen T et al. Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer. Clin. Chem. 57(1), 84-91 (2011
-
(2011)
Clin. Chem.
, vol.57
, Issue.1
, pp. 84-91
-
-
Asaga, S.1
Kuo, C.2
Nguyen, T.3
-
38
-
-
55549120234
-
MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage lymph node metastasis and patient poor prognosis
-
Yan LX, Huang XF, Shao Q et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 14(11), 2348-2360 (2008
-
(2008)
RNA
, vol.14
, Issue.11
, pp. 2348-2360
-
-
Yan, L.X.1
Huang, X.F.2
Shao, Q.3
-
39
-
-
0032526094
-
Mapping of ER gene CpG island methylation-specific polymerase chain reaction
-
Lapidus RG, Nass SJ, Butash KA et al. Mapping of ER gene CpG island methylation-specific polymerase chain reaction. Cancer Res. 58(12), 2515-2519 (1998
-
(1998)
Cancer Res.
, vol.58
, Issue.12
, pp. 2515-2519
-
-
Lapidus, R.G.1
Nass, S.J.2
Butash, K.A.3
-
40
-
-
0028318783
-
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
-
Ottaviano YL, Issa JP, Parl FF et al. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res. 54(10), 2552-2555 (1994
-
(1994)
Cancer Res.
, vol.54
, Issue.10
, pp. 2552-2555
-
-
Ottaviano, Y.L.1
Issa, J.P.2
Parl, F.F.3
-
41
-
-
0029002319
-
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression
-
Ferguson AT, Lapidus RG, Baylin SB, Davidson NE. Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression. Cancer Res. 55(11), 2279-2283 (1995
-
(1995)
Cancer Res.
, vol.55
, Issue.11
, pp. 2279-2283
-
-
Ferguson, A.T.1
Lapidus, R.G.2
Baylin, S.B.3
Davidson, N.E.4
-
42
-
-
1542787625
-
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-a ER in ER-negative human breast cancer cell lines
-
Yan L, Nass SJ, Smith D et al. Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-a(ER) in ER-negative human breast cancer cell lines. Cancer Biol. Ther. 2(5), 552-556 (2003
-
(2003)
Cancer Biol. Ther.
, vol.2
, Issue.5
, pp. 552-556
-
-
Yan, L.1
Nass, S.J.2
Smith, D.3
-
43
-
-
0033945861
-
DNMT1 binds HDAC2 and a new co-repressor DMAP1 to form a complex at replication foci
-
Rountree MR, Bachman KE, Baylin SB. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat. Genet. 25(3), 269-277 (2000
-
(2000)
Nat. Genet.
, vol.25
, Issue.3
, pp. 269-277
-
-
Rountree, M.R.1
Bachman, K.E.2
Baylin, S.B.3
-
44
-
-
8544226964
-
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer
-
Leu YW, Yan PS, Fan M et al. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res. 64(22), 8184-8192 (2004
-
(2004)
Cancer Res.
, vol.64
, Issue.22
, pp. 8184-8192
-
-
Leu, Y.W.1
Yan, P.S.2
Fan, M.3
-
45
-
-
67650135755
-
Mi R-22 inhibits estrogen signaling by directly targeting the estrogen receptor amRNA
-
Pandey DP, Picard D. miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor amRNA. Mol. Cell. Biol. 29(13), 3783-3790 (2009
-
(2009)
Mol. Cell. Biol.
, vol.29
, Issue.13
, pp. 3783-3790
-
-
Pandey, D.P.1
Picard, D.2
-
46
-
-
78651313568
-
Promoter CpG island hypermethylation during breast cancer progression
-
Park SY, Kwon HJ, Lee HE et al. Promoter CpG island hypermethylation during breast cancer progression. Virchows Arch. 458, 73-84 (2011
-
(2011)
Virchows Arch.
, vol.458
, pp. 73-84
-
-
Park, S.Y.1
Kwon, H.J.2
Lee, H.E.3
-
47
-
-
38749121383
-
Array-based multiplex analysis of DNA methylation in breast cancer tissues
-
Melnikov AA, Scholtens DM, Wiley EL, Khan SA, Levenson VV. Array-based multiplex analysis of DNA methylation in breast cancer tissues. J. Mol. Diagn. 10(1), 93-101 (2008
-
(2008)
J. Mol. Diagn.
, vol.10
, Issue.1
, pp. 93-101
-
-
Melnikov, A.A.1
Scholtens, D.M.2
Wiley, E.L.3
Khan, S.A.4
Levenson, V.V.5
-
48
-
-
79959689003
-
Delineating an epigenetic continuum for initiation transformation and progression to breast cancer
-
Chen KM, Stephen JK, Raji U, Worsham MJ. Delineating an epigenetic continuum for initiation, transformation and progression to breast cancer. Cancers (Basel) 3(2), 1580-1592 (2011
-
(2011)
Cancers Basel
, vol.3
, Issue.2
, pp. 1580-1592
-
-
Chen, K.M.1
Stephen, J.K.2
Raji, U.3
Worsham, M.J.4
-
49
-
-
34648846673
-
Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma
-
Pasquali L, Bedeir A, Ringquist S et al. Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma. Cancer Lett. 257(1), 136-144 (2007
-
(2007)
Cancer Lett.
, vol.257
, Issue.1
, pp. 136-144
-
-
Pasquali, L.1
Bedeir, A.2
Ringquist, S.3
-
50
-
-
70350105624
-
Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression
-
Hoque MO, Prencipe M, Poeta ML et al. Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression. Cancer Epidemiol. Biomarkers Prev. 18(10), 2694-2700 (2009
-
(2009)
Cancer Epidemiol. Biomarkers Prev.
, vol.18
, Issue.10
, pp. 2694-2700
-
-
Hoque, M.O.1
Prencipe, M.2
Poeta, M.L.3
-
51
-
-
77956058519
-
Simultaneous analysis of the methylation profile of 26 cancer related regions in invasive breast carcinomas by MS-MLPA and drMS-MLPA
-
Marzese DM, Gago FE, Vargas-Roig LM, Roqué M. Simultaneous analysis of the methylation profile of 26 cancer related regions in invasive breast carcinomas by MS-MLPA and drMS-MLPA. Mol. Cell. Probes 24(5), 271-280 (2010
-
(2010)
Mol. Cell. Probes
, vol.24
, Issue.5
, pp. 271-280
-
-
Marzese, D.M.1
Gago, F.E.2
Vargas-Roig, L.M.3
Roqué, M.4
-
52
-
-
84868211985
-
Hypomethylation of LINE-1 in primary tumor has poor prognosis in young breast cancer patients: A retrospective cohort study
-
10.1007/s10549-012-2038-0 Epub ahead of print
-
van Hoesel AQ, van de Velde CJH, Kuppen PJK et al. Hypomethylation of LINE-1 in primary tumor has poor prognosis in young breast cancer patients: a retrospective cohort study. Breast Cancer Res. Treat. doi:10.1007/s10549-012- 2038-0 (2012) (Epub ahead of print
-
(2012)
Breast Cancer Res. Treat.
-
-
Van Hoesel, A.Q.1
Van De Velde, C.J.H.2
Kuppen, P.J.K.3
-
53
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
USA
-
Toyota M, Ahuja N, Ohe-Toyota M et al. CpG island methylator phenotype in colorectal cancer. Proc. Natl Acad. Sci. USA 96(15), 8681-8686 (1999
-
(1999)
Proc. Natl Acad. Sci.
, vol.96
, Issue.15
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
-
54
-
-
33645801603
-
Genetic epigenetic and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with epstein-barr virus
-
Kusano M, Toyota M, Suzuki H et al. Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus. Cancer 106(7), 1467-1479 (2006
-
(2006)
Cancer
, vol.106
, Issue.7
, pp. 1467-1479
-
-
Kusano, M.1
Toyota, M.2
Suzuki, H.3
-
55
-
-
63449140854
-
CpG island methylator phenotype predicts progression of malignant melanoma
-
Tanemura A, Terando AM, Sim MS et al. CpG island methylator phenotype predicts progression of malignant melanoma. Clin. Cancer Res. 15(5), 1801-1807 (2009
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.5
, pp. 1801-1807
-
-
Tanemura, A.1
Terando, A.M.2
Sim, M.S.3
-
56
-
-
79953123510
-
Breast cancer methylomes establish an epigenomic foundation for metastasis
-
Fang F, Turcan S, Rimner A et al. Breast cancer methylomes establish an epigenomic foundation for metastasis. Sci. Transl. Med. 3(75), 75ra25 (2011
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.75
, pp. 75-25
-
-
Fang, F.1
Turcan, S.2
Rimner, A.3
-
57
-
-
77954643026
-
CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma
-
Jing F, Yuping W, Yong C et al. CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma. Tumour Biol. 31(4), 321-331 (2010
-
(2010)
Tumour Biol.
, vol.31
, Issue.4
, pp. 321-331
-
-
Jing, F.1
Yuping, W.2
Yong, C.3
-
58
-
-
39649104991
-
DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
-
Roll JD, Rivenbark AG, Jones WD, Coleman WB. DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines. Mol. Cancer 7, 15 (2008
-
(2008)
Mol. Cancer
, vol.7
, pp. 15
-
-
Roll, J.D.1
Rivenbark, A.G.2
Jones, W.D.3
Coleman, W.B.4
-
59
-
-
2342556584
-
Cadherin switch in tumor progression
-
Hazan RB, Qiao R, Keren R, Badano I, Suyama K. Cadherin switch in tumor progression. Ann. N. Y. Acad. Sci. 1014, 155-163 (2004
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1014
, pp. 155-163
-
-
Hazan, R.B.1
Qiao, R.2
Keren, R.3
Badano, I.4
Suyama, K.5
-
60
-
-
77953879928
-
Involvement of members of the cadherin superfamily in cancer
-
Berx G, van Roy F. Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb. Perspect. Biol. 1(6), A003129 (2009
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
, Issue.6
-
-
Berx, G.1
Van Roy, F.2
-
61
-
-
0035229053
-
Differential expression of E-cadherin in lobular and ductal neoplasms of the breast and its biologic and diagnostic implications
-
Acs G, Lawton TJ, Rebbeck TR, LiVolsi VA, Zhang PJ. Differential expression of E-cadherin in lobular and ductal neoplasms of the breast and its biologic and diagnostic implications. Am. J. Clin. Pathol. 115(1), 85-98 (2001
-
(2001)
Am. J. Clin. Pathol.
, vol.115
, Issue.1
, pp. 85-98
-
-
Acs, G.1
Lawton, T.J.2
Rebbeck, T.R.3
LiVolsi, V.A.4
Zhang, P.J.5
-
62
-
-
0035342577
-
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast
-
Droufakou S, Deshmane V, Roylance R, Hanby A, Tomlinson I, Hart IR. Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int. J. Cancer 92(3), 404-408 (2001
-
(2001)
Int. J. Cancer
, vol.92
, Issue.3
, pp. 404-408
-
-
Droufakou, S.1
Deshmane, V.2
Roylance, R.3
Hanby, A.4
Tomlinson, I.5
Hart, I.R.6
-
63
-
-
34247550919
-
CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer
-
Caldeira JRF, Prando EC, Quevedo FC, Neto FAM, Rainho CA, Rogatto SR. CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer. BMC Cancer 6, 48 (2006
-
(2006)
BMC Cancer
, vol.6
, pp. 48
-
-
Caldeira, J.R.F.1
Prando, E.C.2
Quevedo, F.C.3
Neto, F.A.M.4
Rainho, C.A.5
Rogatto, S.R.6
-
64
-
-
0034662645
-
Aberrant methylation of the estrogen receptor and E-cadherin in 5 CpG islands increases with malignant progression in breast cancer
-
Nass SJ, Herman JG, Gabrielson E et al. Aberrant methylation of the estrogen receptor and E-cadherin in 5' CpG islands increases with malignant progression in breast cancer. Cancer Res. 60(16), 4346-4348 (2000
-
(2000)
Cancer Res.
, vol.60
, Issue.16
, pp. 4346-4348
-
-
Nass, S.J.1
Herman, J.G.2
Gabrielson, E.3
-
65
-
-
66849126153
-
Epigenetic silencing in non-neoplastic epithelia identifies E-cadherin CDH1 as a target for chemoprevention of lobular neoplasia
-
Zou D, Yoon HS, Perez D, Weeks RJ, Guilford P, Humar B. Epigenetic silencing in non-neoplastic epithelia identifies E-cadherin (CDH1) as a target for chemoprevention of lobular neoplasia. J. Pathol. 218(2), 265-272 (2009
-
(2009)
J. Pathol.
, vol.218
, Issue.2
, pp. 265-272
-
-
Zou, D.1
Yoon, H.S.2
Perez, D.3
Weeks, R.J.4
Guilford, P.5
Humar, B.6
-
66
-
-
78149329114
-
Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma
-
de Maat MF, Narita N, Benard A et al. Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma. Am. J. Pathol. 177(5), 2347-2356 (2010
-
(2010)
Am. J. Pathol.
, vol.177
, Issue.5
, pp. 2347-2356
-
-
De Maat, M.F.1
Narita, N.2
Benard, A.3
-
67
-
-
0033229890
-
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype
-
Toyota M, Ahuja N, Suzuki H et al. Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res. 59(21), 5438-5442 (1999
-
(1999)
Cancer Res.
, vol.59
, Issue.21
, pp. 5438-5442
-
-
Toyota, M.1
Ahuja, N.2
Suzuki, H.3
-
68
-
-
36549029229
-
Correlation between CpG methylation profiles and hormone receptor status in breast cancers
-
Feng W, Shen L, Wen S et al. Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res. 9(4), R57 (2007
-
(2007)
Breast Cancer Res.
, vol.9
, Issue.4
-
-
Feng, W.1
Shen, L.2
Wen, S.3
-
69
-
-
77958540564
-
Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
-
Holm K, Hegardt C, Staaf J et al. Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns. Breast Cancer Res. 12(3), R36 (2010
-
(2010)
Breast Cancer Res.
, vol.12
, Issue.3
-
-
Holm, K.1
Hegardt, C.2
Staaf, J.3
-
70
-
-
77649238322
-
DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status
-
Flanagan JM, Cocciardi S, Waddell N et al. DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. Am. J. Hum. Genet. 86(3), 420-433 (2010
-
(2010)
Am. J. Hum. Genet.
, vol.86
, Issue.3
, pp. 420-433
-
-
Flanagan, J.M.1
Cocciardi, S.2
Waddell, N.3
-
71
-
-
69949189728
-
MicroRNA signatures predict oestrogen receptor progesterone receptor and HER2 n receptor status in breast cancer
-
Lowery AJ, Miller N, Devaney A et al. MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/n receptor status in breast cancer. Breast Cancer Res. 11(3), R27 (2009
-
(2009)
Breast Cancer Res.
, vol.11
, Issue.3
-
-
Lowery, A.J.1
Miller, N.2
Devaney, A.3
-
72
-
-
78649735494
-
Molecularly targeted endocrine therapies for breast cancer
-
Orlando L, Schiavone P, Fedele P et al. Molecularly targeted endocrine therapies for breast cancer. Cancer Treat. Rev. 36(Suppl. 3), S67-S71 (2010
-
(2010)
Cancer Treat. Rev.
, vol.36
, Issue.3
-
-
Orlando, L.1
Schiavone, P.2
Fedele, P.3
-
73
-
-
33746159061
-
Estrogen receptor-amethylation predicts melanoma progression
-
Mori T, Martinez SR, O'Day SJ et al. Estrogen receptor-amethylation predicts melanoma progression. Cancer Res. 66(13), 6692-6698 (2006
-
(2006)
Cancer Res.
, vol.66
, Issue.13
, pp. 6692-6698
-
-
Mori, T.1
Martinez, S.R.2
Oday, S.J.3
-
74
-
-
78650264443
-
Downregulation of miR-342 is associated with tamoxifen resistant breast tumors
-
Cittelly DM, Das PM, Spoelstra NS et al. Downregulation of miR-342 is associated with tamoxifen resistant breast tumors. Mol. Cancer 9, 317 (2010
-
(2010)
Mol. Cancer
, vol.9
, pp. 317
-
-
Cittelly, D.M.1
Das, P.M.2
Spoelstra, N.S.3
-
76
-
-
33947281469
-
Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: Comparison with historical experience
-
Kantarjian HM, O'Brien S, Huang X et al. Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience. Cancer 109(6), 1133-1137 (2007
-
(2007)
Cancer
, vol.109
, Issue.6
, pp. 1133-1137
-
-
Kantarjian, H.M.1
Obrien, S.2
Huang, X.3
-
77
-
-
79958084461
-
A Phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer
-
Munster PN, Thurn KT, Thomas S et al. A Phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br. J. Cancer 104(12), 1828-1835 (2011
-
(2011)
Br. J. Cancer
, vol.104
, Issue.12
, pp. 1828-1835
-
-
Munster, P.N.1
Thurn, K.T.2
Thomas, S.3
-
78
-
-
44749085668
-
ER anegative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor
-
Fan J, Yin WJ, Lu JS et al. ER anegative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. J. Cancer Res. Clin. Oncol. 134(8), 883-890 (2008
-
(2008)
J. Cancer Res. Clin. Oncol.
, vol.134
, Issue.8
, pp. 883-890
-
-
Fan, J.1
Yin, W.J.2
Lu, J.S.3
-
79
-
-
33745685866
-
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: Tamoxifen-bound reactivated ER recruits distinctive corepressor complexes
-
Sharma D, Saxena NK, Davidson NE, Vertino PM. Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. Cancer Res. 66(12), 6370-6378 (2006
-
(2006)
Cancer Res.
, vol.66
, Issue.12
, pp. 6370-6378
-
-
Sharma, D.1
Saxena, N.K.2
Davidson, N.E.3
Vertino, P.M.4
-
80
-
-
0242330341
-
A novel histone deacetylase inhibitor scriptaid enhances expression of functional estrogen receptor a ER in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine
-
Keen JC, Yan L, Mack KM et al. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor a(ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. Breast Cancer Res. Treat. 81(3), 177-186 (2003
-
(2003)
Breast Cancer Res. Treat.
, vol.81
, Issue.3
, pp. 177-186
-
-
Keen, J.C.1
Yan, L.2
Mack, K.M.3
-
81
-
-
33847111684
-
Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor a ER gene expression without loss of DNA hypermethylation
-
Zhou Q, Atadja P, Davidson NE. Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor a(ER) gene expression without loss of DNA hypermethylation. Cancer Biol. Ther. 6(1), 64-69 (2007
-
(2007)
Cancer Biol. Ther.
, vol.6
, Issue.1
, pp. 64-69
-
-
Zhou, Q.1
Atadja, P.2
Davidson, N.E.3
-
82
-
-
0034671304
-
Transcriptional activation of estrogen receptor ain human breast cancer cells by histone deacetylase inhibition
-
Yang X, Ferguson AT, Nass SJ et al. Transcriptional activation of estrogen receptor ain human breast cancer cells by histone deacetylase inhibition. Cancer Res. 60(24), 6890-6894 (2000
-
(2000)
Cancer Res.
, vol.60
, Issue.24
, pp. 6890-6894
-
-
Yang, X.1
Ferguson, A.T.2
Nass, S.J.3
-
83
-
-
70449701913
-
Epigenetic cross-talk between DNA methylation and histone modifications in human cancers
-
Kondo Y. Epigenetic cross-talk between DNA methylation and histone modifications in human cancers. Yonsei Med. J. 50(4), 455-463 (2009
-
(2009)
Yonsei Med. J.
, vol.50
, Issue.4
, pp. 455-463
-
-
Kondo, Y.1
-
84
-
-
65949086183
-
Global histone modifications in breast cancer correlate with tumor phenotypes prognostic factors and patient outcome
-
Elsheikh SE, Green AR, Rakha EA et al. Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome. Cancer Res. 69(9), 3802-3809 (2009
-
(2009)
Cancer Res.
, vol.69
, Issue.9
, pp. 3802-3809
-
-
Elsheikh, S.E.1
Green, A.R.2
Rakha, E.A.3
-
85
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
USA
-
Kleer CG, Cao Q, Varambally S et al. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc. Natl Acad. Sci. USA 100(20), 11606-11611 (2003
-
(2003)
Proc. Natl Acad. Sci.
, vol.100
, Issue.20
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
-
86
-
-
77949617195
-
An estrogen receptor asuppressor microRNA-22 is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples
-
Xiong J, Yu D, Wei N et al. An estrogen receptor asuppressor, microRNA-22, is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples. FEBS J. 277(7), 1684-1694 (2010
-
(2010)
FEBS J.
, vol.277
, Issue.7
, pp. 1684-1694
-
-
Xiong, J.1
Yu, D.2
Wei, N.3
-
87
-
-
34250843675
-
The micro-ribonucleic acid miRNA miR-206 targets the human estrogen receptor-a ERa and represses ER amessenger RNA and protein expression in breast cancer cell lines
-
Adams BD, Furneaux H, White BA. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-a(ERa) and represses ERamessenger RNA and protein expression in breast cancer cell lines. Mol. Endocrinol. 21(5), 1132-1147 (2007
-
(2007)
Mol. Endocrinol.
, vol.21
, Issue.5
, pp. 1132-1147
-
-
Adams, B.D.1
Furneaux, H.2
White, B.A.3
-
88
-
-
57649174634
-
MicroRNA-221 222 negatively regulates estrogen receptor aand is associated with tamoxifen resistance in breast cancer
-
Zhao JJ, Lin J, Yang H et al. MicroRNA-221/222 negatively regulates estrogen receptor aand is associated with tamoxifen resistance in breast cancer. J. Biol. Chem. 283(45), 31079-31086 (2008
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.45
, pp. 31079-31086
-
-
Zhao, J.J.1
Lin, J.2
Yang, H.3
-
89
-
-
77950867869
-
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells
-
Billam M, Sobolewski MD, Davidson NE. Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells. Breast Cancer Res. Treat. 120, 581-592 (2010
-
(2010)
Breast Cancer Res. Treat.
, vol.120
, pp. 581-592
-
-
Billam, M.1
Sobolewski, M.D.2
Davidson, N.E.3
|