Development of drug delivery systems for the dermal application of therapeutic DNAzymes

International Journal of Pharmaceutics

Volumn 431, Issue 1-2, 2012, Pages 61-69

  Schmidts, Thomas ^a   Marquardt, Kay ^a   Schlupp, Peggy ^a   Dobler, Dorota ^a   Heinz, Florian ^a   Mäder, Ulf ^a   Garn, Holger ^b   Renz, Harald ^c   Zeitvogel, Jana ^d   Werfel, Thomas ^d   Runkel, Frank ^a  

^a TECHNISCHE HOCHSCHULE MITTELHESSEN   (Germany)

^b Sterna Biologicals GmbH and Co KG   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

DNAzyme; Oligonucleotides; Skin penetration; Submicron emulsion; W O W multiple emulsion

Indexed keywords

DNA; DNAZYME; DRUG CARRIER; ENZYME; UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; DRUG UPTAKE; EMULSION; FLOW CYTOMETRY; PHYSICAL CHEMISTRY; PRESERVATION; PRIORITY JOURNAL;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, CATALYTIC; DRUG CARRIERS; EMULSIONS; SKIN; SKIN ABSORPTION; SWINE;

EID: 84861337137     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.034     Document Type: Article

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