The intertransmembrane region of Kaposi's sarcoma-associated herpesvirus modulator of immune recognition 2 contributes to B7-2 downregulation

Journal of Virology

Volumn 86, Issue 9, 2012, Pages 5288-5296

  Kajikawa, Mizuho ^a   Li, Pai Chi ^a,b   Goto, Eiji ^a   Miyashita, Naoyuki ^b   Aoki Kawasumi, Masami ^a   Mito Yoshida, Mari ^a   Ikegaya, Mika ^a   Sugita, Yuji ^b   Ishido, Satoshi ^a  

^a RIKEN Center for Integrative Medical Sciences   (Japan)

^b RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CD86 ANTIGEN; CD8ALPHA ANTIGEN; MODULATOR OF IMMUNE RECOGNITION 1; MODULATOR OF IMMUNE RECOGNITION 2; PHENYLALANINE; SERINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CHIMERA; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; INTERTRANSMEMBRANE REGION; JUXTAMEMBRANE REGION; MUTAGENESIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; VIRUS ENVELOPE;

AMINO ACIDS; ANTIGENS, CD86; CELL LINE; DOWN-REGULATION; HERPESVIRUS 8, HUMAN; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS;

HUMAN HERPESVIRUS 8;

EID: 84861302924     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00219-12     Document Type: Article

References (41)

1. Barber DF, Faure M, Long EO. 2004. LFA-1 contributes an early signal for NK cell cytotoxicity. J. Immunol. 173:3653-3659.
2. Bjorkman PJ, Parham P. 1990. Structure, function, and diversity of class I major histocompatibility complex molecules. Annu. Rev. Biochem. 59: 253-288.
3. Boname JM, Stevenson PG. 2001. MHC class I ubiquitination by a viral PHD/LAP finger protein. Immunity 15:627-636.
4. Brooks BR, et al. 2009. CHARMM: the biomolecular simulation program. J. Comput. Chem. 30:1545-1614.
5. Bryceson YT, March ME, Barber DF, Ljunggren HG, Long EO. 2005. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J. Exp. Med. 202:1001-1012.
6. Bu L, Im W, Brooks CL III. 2007. Membrane assembly of simple helix homo-oligomers studied via molecular dynamics simulations. Biophys. J. 92:854-863.
7. Cadwell K, Coscoy L. 2008. The specificities of Kaposi's sarcomaassociated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets. J. Virol. 82:4184-4189.
8. Coscoy L. 2007. Immune evasion by Kaposi's sarcoma-associated herpesvirus. Nat. Rev. Immunol. 7:391-401.
9. Coscoy L, Ganem D. 2001. A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. J. Clin. Invest. 107:1599-1606.
10. Coscoy L, Sanchez DJ, Ganem D. 2001. A novel class of herpesvirusencoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J. Cell Biol. 155:1265-1273.
11. Feig M, Karanicolas J, Brooks CL III. 2004. MMTSB Tool Set: enhanced sampling and multiscale modeling methods for applications in structural biology. J. Mol. Graph. Model. 22:377-395.
12. Hewitt EW, et al. 2002. Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J. 21:2418-2429.
13. Hirokawa T, Boon-Chieng S, Mitaku S. 1998. SOSUI: classification and secondary structure prediction system for membrane proteins. Bioinformatics 14:378-379.
14. Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
15. Humphrey W, Dalke A, Schulten K. 1996. VMD: visual molecular dynamics. J. Mol. Graph. 14:33-38, 27-28.
16. Ikemizu S, et al. 2000. Structure and dimerization of a soluble form of B7-1. Immunity 12:51-60.
17. Im W, Feig M, Brooks CL III. 2003. An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins. Biophys. J. 85:2900-2918.
18. Ishido S, et al. 2000. Inhibition of natural killer cell-mediated cytotoxicity by Kaposi's sarcoma-associated herpesvirus K5 protein. Immunity 13: 365-374.
19. Ishido S, Wang C, Lee BS, Cohen GB, Jung JU. 2000. Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcomaassociated herpesvirus K3 and K5 proteins. J. Virol. 74:5300-5309.
20. Jonjić S, Babic M, Polic B, Krmpotic A. 2008. Immune evasion of natural killer cells by viruses. Curr. Opin. Immunol. 20:30-38.
21. Letunic I, Doerks T, Bork P. 2009. SMART 6: recent updates and new developments. Nucleic Acids Res. 37:D229-D232.
22. Liang C, Lee JS, Jung JU. 2008. Immune evasion in Kaposi's sarcomaassociated herpes virus associated oncogenesis. Semin. Cancer Biol. 18: 423-436.
23. Mackerell AD Jr, Feig M, Brooks CL III. 2004. Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. J. Comput. Chem. 25:1400-1415.
24. Modis Y, Ogata S, Clements D, Harrison SC. 2004. Structure of the dengue virus envelope protein after membrane fusion. Nature 427:313-319.
25. Nicholas J, et al. 1997. A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins. J. Virol. 71:1963-1974.
26. Ohmura-Hoshino M, et al. 2006. A novel family of membrane-bound E3 ubiquitin ligases. J. Biochem. 140:147-154.
27. Orange JS, Fassett MS, Koopman LA, Boyson JE, Strominger JL. 2002. Viral evasion of natural killer cells. Nat. Immunol. 3:1006-1012.
28. Petersen JL, Morris CR, Solheim JC. 2003. Virus evasion of MHC class I molecule presentation. J. Immunol. 171:4473-4478.
29. Ploegh HL. 1998. Viral strategies of immune evasion. Science 280:248-253.
30. Raulet DH. 1996. Recognition events that inhibit and activate natural killer cells. Curr. Opin. Immunol. 8:372-377.
31. Russo JJ, et al. 1996. Nucleotide sequence of the Kaposi sarcomaassociated herpesvirus (HHV8). Proc. Natl. Acad. Sci. U. S. A. 93:14862-14867.
32. Sanchez DJ, Coscoy L, Ganem D. 2002. Functional organization of MIR2, a novel viral regulator of selective endocytosis. J. Biol. Chem. 277: 6124-6130.
33. Schultz J, Milpetz F, Bork P, Ponting CP. 1998. SMART, a simple modular architecture research tool: identification of signaling domains. Proc. Natl. Acad. Sci. U. S. A. 95:5857-5864.
34. Stopar D, Spruijt RB, Hemminga MA. 2006. Anchoring mechanisms of membrane-associated M13 major coat protein. Chem. Phys. Lipids 141: 83-93.
35. Sugita Y, Okamoto Y. 1999. Replica-exchange molecular dynamics method for protein folding. Chem. Phys. Lett. 314:141-151.
36. Tanaka K, Kasahara M. 1998. The MHC class I ligand-generating system: roles of immunoproteasomes and the interferon-gamma-inducible proteasome activator PA28. Immunol. Rev. 163:161-176.
37. Ulmschneider MB, Sansom MS. 2001. Amino acid distributions in integral membrane protein structures. Biochim. Biophys. Acta 1512:1-14.
38. Victor K, Jacob J, Cafiso DS. 1999. Interactions controlling the membrane binding of basic protein domains: phenylalanine and the attachment of the myristoylated alanine-rich C-kinase substrate protein to interfaces. Biochemistry 38:12527-12536.
39. Whitby D, Boshoff C. 1998. Kaposi's sarcoma herpesvirus as a new paradigm for virus-induced oncogenesis. Curr. Opin. Oncol. 10:405-412.
40. Wilson JL, et al. 1999. NK cell triggering by the human costimulatory molecules CD80 and CD86. J. Immunol. 163:4207-4212.
41. Winter U, Chen X, Fasshauer D. 2009. A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly. J. Biol. Chem. 284:31817-31826.