Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding

Molecular Endocrinology

Volumn 26, Issue 6, 2012, Pages 926-939

  Chiamolera, Maria I ^a   Sidhaye, Aniket R ^b   Matsumoto, Shunichi ^b   He, Qiyi ^b   Hashimoto, Koshi ^c   Ortiga Carvalho, Tania M ^d   Wondisford, Fredric E ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GUNMA UNIVERSITY   (Japan)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Ligands: thyroid hormone; Nuclear receptors: TR ; TR

Indexed keywords

DNA; SHORT HAIRPIN RNA; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROTROPIN;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; GENE EXPRESSION; GENE SILENCING; IN VIVO STUDY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; RNA ANALYSIS; TSH SECRETING CELL; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELL LINE; DNA; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, THYROID HORMONE; RNA INTERFERENCE; RNA, MESSENGER; THYROTROPHS; THYROTROPIN, BETA SUBUNIT; TRANSCRIPTION, GENETIC; TRIIODOTHYRONINE;

EID: 84861211282     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1290     Document Type: Article

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