Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation

Journal of Biological Chemistry

Volumn 278, Issue 2, 2003, Pages 732-738

  Shibusawa, Nobuyuki ^a   Hollenberg, Anthony N ^b   Wondisford, Fredric E ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GELS; HORMONES;

HORMONE RECEPTORS;

GENES;

DNA; GLUCOCORTICOID RECEPTOR; GS125 MUTANT PROTEIN; MUTANT PROTEIN; PROTEIN SUBUNIT; PROTIRELIN; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BETA; THYROTROPIN; THYROTROPIN ALPHA; THYROTROPIN BETA; TRANSCRIPTION COFACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BIOASSAY; COMPOSITE THYROID HORMONE RECEPTOR GLUCOCORTICOID RECEPTOR RESPONSE ELEMENT; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE REPRESSION; HORMONE RECEPTOR INTERACTION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; NEGATIVE FEEDBACK; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; THYROID HORMONE RESPONSE ELEMENT; TRANSACTIVATION; TRANSIENT TRANSFECTION ASSAY; TWO HYBRID SYSTEM; ALPHA CHAIN; AMINO ACID SEQUENCE; BINDING SITE; CELL CULTURE; CHEMISTRY; DNA RESPONSIVE ELEMENT; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

MAMMALIA;

AMINO ACID SEQUENCE; BINDING SITES; CELLS, CULTURED; DNA; FEEDBACK; GENE EXPRESSION REGULATION; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MOLECULAR SEQUENCE DATA; PITUITARY-ADRENAL SYSTEM; PROMOTER REGIONS (GENETICS); RECEPTORS, THYROID HORMONE; RESPONSE ELEMENTS; THYROID HORMONE RECEPTORS BETA; THYROID HORMONES; TRANSCRIPTION, GENETIC;

EID: 0037428431     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207264200     Document Type: Article

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