-
1
-
-
0023025178
-
The c-erb-A protein is a high-affinity receptor for thyroid hormone
-
DOI 10.1038/324635a0
-
Sap J, Muñoz A, Damm K, Goldberg Y, Ghysdael J, Leutz A, Beug H, Vennström B 1986 The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature 324:635-640 (Pubitemid 17206350)
-
(1986)
Nature
, vol.324
, Issue.6098
, pp. 635-640
-
-
Sap, J.1
Munoz, A.2
Damm, K.3
-
2
-
-
0022998995
-
The c-erb-A gene encodes a thyroid hormone receptor
-
DOI 10.1038/324641a0
-
Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, Evans RM 1986 The c-erb-A gene encodes a thyroid hormone receptor. Nature 324:641-646 (Pubitemid 17206351)
-
(1986)
Nature
, vol.324
, Issue.6098
, pp. 641-646
-
-
Weinberger, C.1
Thompson, C.C.2
Ong, E.S.3
-
3
-
-
77953639982
-
Molecular aspects of thyroid hormone actions
-
Cheng SY, Leonard JL, Davis PJ 2010 Molecular aspects of thyroid hormone actions. Endocr Rev 31:139-170
-
(2010)
Endocr Rev
, vol.31
, pp. 139-170
-
-
Cheng, S.Y.1
Leonard, J.L.2
Davis, P.J.3
-
4
-
-
27744449069
-
Adaptive activation of thyroid hormone and energy expenditure
-
DOI 10.1007/s10540-005-2885-6
-
Bianco AC, Maia AL, da Silva WS, Christoffolete MA 2005 Adaptive activation of thyroid hormone and energy expenditure. Biosci Rep 25:191-208 (Pubitemid 41613787)
-
(2005)
Bioscience Reports
, vol.25
, Issue.3-4
, pp. 191-208
-
-
Bianco, A.C.1
Maia, A.L.2
Da, S.W.S.3
Christoffolete, M.A.4
-
5
-
-
0347364651
-
Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor
-
DOI 10.1073/pnas.2136689100
-
Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, Fletterick RJ 2003 Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor. Proc Natl Acad Sci USA 100:15358-15363 (Pubitemid 38020994)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.26
, pp. 15358-15363
-
-
Borngraeber, S.1
Budny, M.-J.2
Chiellini, G.3
Cunha-Lima, S.T.4
Togashi, M.5
Webb, P.6
Baxter, J.D.7
Scanlan, T.S.8
Fletterick, R.J.9
-
6
-
-
0032101890
-
A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor
-
Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS 1998 A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chem Biol 5:299-306
-
(1998)
Chem Biol
, vol.5
, pp. 299-306
-
-
Chiellini, G.1
Apriletti, J.W.2
Yoshihara, H.A.3
Baxter, J.D.4
Ribeiro, R.C.5
Scanlan, T.S.6
-
7
-
-
33751550166
-
The pharmacology and classification of the nuclear receptor superfamily: Thyroid hormone receptors
-
International Union of Pharmacology. LIX
-
Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennström B, Samarut J 2006 International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors. Pharmacol Rev 58: 705-711
-
(2006)
Pharmacol Rev
, vol.58
, pp. 705-711
-
-
Flamant, F.1
Baxter, J.D.2
Forrest, D.3
Refetoff, S.4
Samuels, H.5
Scanlan, T.S.6
Vennström, B.7
Samarut, J.8
-
8
-
-
39449118862
-
Effects of thyroid hormone analogs on lipid metabolism and thermogenesis
-
DOI 10.1089/thy.2007.0288
-
Ribeiro MO 2008 Effects of thyroid hormone analogs on lipid metabolism and thermogenesis. Thyroid 18:197-203 (Pubitemid 351271536)
-
(2008)
Thyroid
, vol.18
, Issue.2
, pp. 197-203
-
-
Ribeiro, M.O.1
-
9
-
-
79951904578
-
In vivo activity of the thyroid hormone receptor β- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain
-
Grijota-Martínez C, Samarut E, Scanlan T, Morte B, Bernal J 2011 In vivo activity of the thyroid hormone receptor β- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain. Endocrinology 152:1136-1142
-
(2011)
Endocrinology
, vol.152
, pp. 1136-1142
-
-
Grijota-Martínez, C.1
Samarut, E.2
Scanlan, T.3
Morte, B.4
Bernal, J.5
-
10
-
-
33846835476
-
Design and characterization of a thyroid hormone receptor α (TRα)-specific agonist
-
Ocasio CA, Scanlan TS 2006 Design and characterization of a thyroid hormone receptor α (TRα)-specific agonist. ACS Chem Biol 1:585-593
-
(2006)
ACS Chem Biol
, vol.1
, pp. 585-593
-
-
Ocasio, C.A.1
Scanlan, T.S.2
-
11
-
-
17744387900
-
The thyroid hormone receptor-β-selective agonist GC-1 differentially affects plasma lipids and cardiac activity
-
DOI 10.1210/en.141.9.3057
-
Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH 2000 The thyroid hormone receptor-β-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology 141:3057-3064 (Pubitemid 32268991)
-
(2000)
Endocrinology
, vol.141
, Issue.9
, pp. 3057-3064
-
-
Trost, S.U.1
Swanson, E.2
Gloss, B.3
Wang-Iverson, D.B.4
Zhang, H.5
Volodarsky, T.6
Grover, G.J.7
Baxter, J.D.8
Chiellini, G.9
Scanlan, T.S.10
Dillmann, W.H.11
-
12
-
-
0142052836
-
Spared bone mass in rats treated with thyroid hormone receptor TRβ-selective compound GC-1
-
Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH 2003 Spared bone mass in rats treated with thyroid hormone receptor TRβ-selective compound GC-1. Am J Physiol Endocrinol Metab 285:E1135-E1141 (Pubitemid 37296337)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.285
, Issue.5
-
-
Freitas, F.R.S.1
Moriscot, A.S.2
Jorgetti, V.3
Soares, A.G.4
Passarelli, M.5
Scanlan, T.S.6
Brent, G.A.7
Bianco, A.C.8
Gouveia, C.H.A.9
-
13
-
-
73649129247
-
Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-β isoform specific and required for adaptive thermogenesis
-
RibeiroMO,Bianco SD, KaneshigeM,Schultz JJ, Cheng SY, Bianco AC, Brent GA 2010 Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-β isoform specific and required for adaptive thermogenesis. Endocrinology 151:432-440
-
(2010)
Endocrinology
, vol.151
, pp. 432-440
-
-
Ribeiro, M.O.1
Bianco, S.D.2
Kaneshige, M.3
Schultz, J.J.4
Cheng, S.Y.5
Bianco, A.C.6
Brent, G.A.7
-
14
-
-
0034932901
-
Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific
-
Ribeiro MO, Carvalho SD, Schultz JJ, Chiellini G, Scanlan TS, Bianco AC, BrentGA2001 Thyroid hormone-sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform-specific. J Clin Invest 108:97-105
-
(2001)
J Clin Invest
, vol.108
, pp. 97-105
-
-
Ribeiro, M.O.1
Carvalho, S.D.2
Schultz, J.J.3
Chiellini, G.4
Scanlan, T.S.5
Bianco, A.C.6
Brent, G.A.7
-
15
-
-
1642505721
-
Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: Selective actions relative to 3,5,3′-triiodo-L-thyronine
-
DOI 10.1210/en.2003-0973
-
Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS 2004 Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3′-triiodo-L-thyronine. Endocrinology 145:1656-1661 (Pubitemid 38402372)
-
(2004)
Endocrinology
, vol.145
, Issue.4
, pp. 1656-1661
-
-
Grover, G.J.1
Egan, D.M.2
Sleph, P.G.3
Beehler, B.C.4
Chiellini, G.5
Nguyen, N.-H.6
Baxter, J.D.7
Scanlan, T.S.8
-
16
-
-
0042734823
-
Selective thyroid hormone receptor-beta activation: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability
-
DOI 10.1073/pnas.1633737100
-
Grover GJ, Mellström K, Ye L, Malm J, Li YL, Bladh LG, Sleph PG, Smith MA, George R, Vennström B, Mookhtiar K, Horvath R, Speelman J, Egan D, Baxter JD 2003 Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability. Proc Natl Acad Sci USA 100:10067-10072 (Pubitemid 37098262)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.17
, pp. 10067-10072
-
-
Grover, G.J.1
Mellstrom, K.2
Ye, L.3
Malm, J.4
Li, Y.-L.5
Bladh, L.-G.6
Sleph, P.G.7
Smith, M.A.8
George, R.9
Vennstrom, B.10
Mookhtiar, K.11
Horvath, R.12
Speelman, J.13
Egan, D.14
Baxter, J.D.15
-
17
-
-
38649135692
-
The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans
-
Berkenstam A, Kristensen J, Mellström K, Carlsson B, Malm J, Rehnmark S, Garg N, Andersson CM, Rudling M, Sjöberg F, Angelin B, Baxter JD 2008 The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans. Proc Natl Acad Sci USA 105:663-667
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 663-667
-
-
Berkenstam, A.1
Kristensen, J.2
Mellström, K.3
Carlsson, B.4
Malm, J.5
Rehnmark, S.6
Garg, N.7
Andersson, C.M.8
Rudling, M.9
Sjöberg, F.10
Angelin, B.11
Baxter, J.D.12
-
18
-
-
79951893427
-
MB07811/MB07344 is a liver-targeted thyroid receptor b-agonist that has additive cholesterol-lowering activity when given in combination with atorvastatin in rabbits and monkeys
-
Abstract
-
Ito BR, Cable EE, Boyer SH, Jiang H, Zhang BH, van Poelj PD, Hecker SJ, Linemeyer DL, Erion MD 2007 MB07811/MB07344 is a liver-targeted thyroid receptor b-agonist that has additive cholesterol-lowering activity when given in combination with atorvastatin in rabbits and monkeys. Thyroid 17:1169 (Abstract)
-
(2007)
Thyroid
, vol.17
, pp. 1169
-
-
Ito, B.R.1
Cable, E.E.2
Boyer, S.H.3
Jiang, H.4
Zhang, B.H.5
Van Poelj, P.D.6
Hecker, S.J.7
Linemeyer, D.L.8
Erion, M.D.9
-
19
-
-
77949349469
-
Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia
-
Ladenson PW, Kristensen JD, Ridgway EC, Olsson AG, Carlsson B, Klein I, Baxter JD, Angelin B 2010 Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. N Engl J Med 362:906-916
-
(2010)
N Engl J Med
, vol.362
, pp. 906-916
-
-
Ladenson, P.W.1
Kristensen, J.D.2
Ridgway, E.C.3
Olsson, A.G.4
Carlsson, B.5
Klein, I.6
Baxter, J.D.7
Angelin, B.8
-
20
-
-
34247344167
-
Thyroid hormone receptor β-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats
-
DOI 10.1677/joe.1.07066
-
VillicevCM,Freitas FR, Aoki MS, Taffarel C, Scanlan TS, Moriscot AS, Ribeiro MO, Bianco AC, Gouveia CH 2007 Thyroid hormone receptor β-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats. J Endocrinol 193:21-29 (Pubitemid 46638528)
-
(2007)
Journal of Endocrinology
, vol.193
, Issue.1
, pp. 21-29
-
-
Villicev, C.M.1
Freitas, F.R.S.2
Aoki, M.S.3
Taffarel, C.4
Scanlan, T.S.5
Moriscot, A.S.6
Ribeiro, M.O.7
Bianco, A.C.8
Gouveia, C.H.A.9
-
21
-
-
70449421916
-
A TRβ-selective agonist confers resistance to diet-induced obesity
-
Amorim BS, Ueta CB, Freitas BC, Nassif RJ, Gouveia CH, Christoffolete MA, Moriscot AS, Lancelloti CL, Llimona F, Barbeiro HV, de Souza HP, Catanozi S, Passarelli M, Aoki MS, Bianco AC, Ribeiro MO 2009 A TRβ-selective agonist confers resistance to diet-induced obesity. J Endocrinol 203:291-299
-
(2009)
J Endocrinol
, vol.203
, pp. 291-299
-
-
Amorim, B.S.1
Ueta, C.B.2
Freitas, B.C.3
Nassif, R.J.4
Gouveia, C.H.5
Christoffolete, M.A.6
Moriscot, A.S.7
Lancelloti, C.L.8
Llimona, F.9
Barbeiro, H.V.10
De Souza, H.P.11
Catanozi, S.12
Passarelli, M.13
Aoki, M.S.14
Bianco, A.C.15
Ribeiro, M.O.16
-
22
-
-
77952325654
-
Impaired metabolic effects of a thyroid hormone receptor β-selective agonist in a mouse model of diet-induced obesity
-
CastilloM,Freitas BC, RoseneML,Drigo RA, Grozovsky R, Maciel RM, Patti ME, Ribeiro MO, Bianco AC 2010 Impaired metabolic effects of a thyroid hormone receptor β-selective agonist in a mouse model of diet-induced obesity. Thyroid 20:545-553
-
(2010)
Thyroid
, vol.20
, pp. 545-553
-
-
Castillo, M.1
Freitas, B.C.2
Rosene, M.L.3
Drigo, R.A.4
Grozovsky, R.5
Maciel, R.M.6
Patti, M.E.7
Ribeiro, M.O.8
Bianco, A.C.9
-
23
-
-
64349087880
-
Brown adipose tissue - When it pays to be inefficient
-
Celi FS 2009 Brown adipose tissue - when it pays to be inefficient. N Engl J Med 360:1553-1556
-
(2009)
N Engl J Med
, vol.360
, pp. 1553-1556
-
-
Celi, F.S.1
-
24
-
-
39549085551
-
The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor
-
DOI 10.1089/thy.2007.0251
-
Hollenberg AN 2008 The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor. Thyroid 18:131-139 (Pubitemid 351278374)
-
(2008)
Thyroid
, vol.18
, Issue.2
, pp. 131-139
-
-
Hollenberg, A.N.1
-
25
-
-
0345257089
-
Differential Effects of Triiodothyronine and the Thyroid Hormone Receptor β-Specific Agonist GC-1 on Thyroid Hormone Target Genes in the Brain
-
DOI 10.1210/en.2003-0633
-
Manzano J, Morte B, Scanlan TS, Bernal J 2003 Differential effects of triiodothyronine and the thyroid hormone receptor β-specific agonist GC-1 on thyroid hormone target genes in the brain. Endocrinology 144:5480-5487 (Pubitemid 37476077)
-
(2003)
Endocrinology
, vol.144
, Issue.12
, pp. 5480-5487
-
-
Manzano, J.1
Morte, B.2
Scanlan, T.S.3
Bernal, J.4
-
26
-
-
0036018277
-
Thyroid hormone and cardiac surgery
-
Klemperer JD 2002 Thyroid hormone and cardiac surgery. Thyroid 12:517-521 (Pubitemid 34721550)
-
(2002)
Thyroid
, vol.12
, Issue.6
, pp. 517-521
-
-
Klemperer, J.D.1
-
27
-
-
33644850947
-
Basic mechanisms of augmentation of antidepressant effects with thyroid hormone
-
Lifschytz T, Segman R, Shalom G, Lerer B, Gur E, Golzer T, Newman ME 2006 Basic mechanisms of augmentation of antidepressant effects with thyroid hormone. Curr Drug Targets 7:203-210
-
(2006)
Curr Drug Targets
, vol.7
, pp. 203-210
-
-
Lifschytz, T.1
Segman, R.2
Shalom, G.3
Lerer, B.4
Gur, E.5
Golzer, T.6
Newman, M.E.7
|