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Volumn 25, Issue 1, 2012, Pages 165-180

Effects of dietary methylmercury on the zebrafish brain: Histological, mitochondrial, and gene transcription analyses

Author keywords

Bioenergetics; Brain; Dietary exposure; Methylmercury; Zebrafish

Indexed keywords

METHYLMERCURY; SUCCINATE DEHYDROGENASE; METHYLMERCURY DERIVATIVE;

EID: 84861208119     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-011-9494-6     Document Type: Article
Times cited : (58)

References (50)
  • 2
    • 0035947014 scopus 로고    scopus 로고
    • Methylmercurymediated inhibition of 3H-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase
    • Allen JW, Mutkus LA, Aschner M (2001) Methylmercurymediated inhibition of 3H-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain Res 902:92-100
    • (2001) Brain Res , vol.902 , pp. 92-100
    • Allen, J.W.1    Mutkus, L.A.2    Aschner, M.3
  • 3
    • 0024399131 scopus 로고
    • Brain, kidney and liver 203Hg-methyl mercury uptake in the rat: Relationship to the neutral amino acid carrier
    • Aschner M (1989) Brain, kidney and liver 203Hg-methyl mercury uptake in the rat: relationship to the neutral amino acid carrier. Pharmacol Toxicol 65:17-20
    • (1989) Pharmacol Toxicol , vol.65 , pp. 17-20
    • Aschner, M.1
  • 4
    • 0034256934 scopus 로고    scopus 로고
    • Methylmercury alters glutamate transport in astrocytes
    • Aschner M, Yao CP, Allen JW, Tan KH (2000) Methylmercury alters glutamate transport in astrocytes. Neurochem Int 37:199-206
    • (2000) Neurochem Int , vol.37 , pp. 199-206
    • Aschner, M.1    Yao, C.P.2    Allen, J.W.3    Tan, K.H.4
  • 5
    • 84984577456 scopus 로고    scopus 로고
    • Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity
    • Aschner M, Syversen T, Souza DO, Rocha JB, Farina M (2007) Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity. Braz J Med Biol Res 40:285-291
    • (2007) Braz J Med Biol Res , vol.40 , pp. 285-291
    • Aschner, M.1    Syversen, T.2    Souza, D.O.3    Rocha, J.B.4    Farina, M.5
  • 6
    • 27144439496 scopus 로고    scopus 로고
    • Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction?
    • Atchison WD (2005) Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction? Trends Pharmacol Sci 26:549-557
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 549-557
    • Atchison, W.D.1
  • 7
    • 75349084368 scopus 로고    scopus 로고
    • In vitro and whole animal evidence that methylmercury disrupts GABAergic systems in discrete brain regions in captive mink
    • Basu N, Scheuhammer AM, Rouvinen-Watt K, Evans RD, Trudeau VL, Chan LHM (2010) In vitro and whole animal evidence that methylmercury disrupts GABAergic systems in discrete brain regions in captive mink. Comp Biochem Physiol C 151:379-385
    • (2010) Comp Biochem Physiol C , vol.151 , pp. 379-385
    • Basu, N.1    Scheuhammer, A.M.2    Rouvinen-Watt, K.3    Evans, R.D.4    Trudeau, V.L.5    Chan, L.H.M.6
  • 8
    • 77957558012 scopus 로고    scopus 로고
    • Responses in the brain proteome of Atlantic cod (Gadus morhua) exposed to methylmercury
    • Berg K, Puntervoll P, Valdersnes S, Goksøyr A (2010) Responses in the brain proteome of Atlantic cod (Gadus morhua) exposed to methylmercury. Aquat Toxicol 100:51-65
    • (2010) Aquat Toxicol , vol.100 , pp. 51-65
    • Berg, K.1    Puntervoll, P.2    Valdersnes, S.3    Goksøyr, A.4
  • 9
    • 0042428778 scopus 로고    scopus 로고
    • Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr
    • Berntssen MHG, Aatland A, Handy RD (2003) Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr. Aquat Toxicol 65:55-72
    • (2003) Aquat Toxicol , vol.65 , pp. 55-72
    • Berntssen, M.H.G.1    Aatland, A.2    Handy, R.D.3
  • 10
    • 15944381278 scopus 로고    scopus 로고
    • Different effects of Hg2? and Cu2? on mussel (Mytilus galloprovincialis) plasma membrane Ca2?-ATPase: Hg2? induction of protein expression
    • Burlando B, Bonomo M, Capri F, Mancinelli G, Pons G, Viarengo A (2004) Different effects of Hg2? and Cu2? on mussel (Mytilus galloprovincialis) plasma membrane Ca2?-ATPase: Hg2? induction of protein expression. Comp Biochem Physiol C 139:201-207
    • (2004) Comp Biochem Physiol C , vol.139 , pp. 201-207
    • Burlando, B.1    Bonomo, M.2    Capri, F.3    Mancinelli, G.4    Pons, G.5    Viarengo, A.6
  • 11
    • 59849103040 scopus 로고    scopus 로고
    • Atenvironmental doses, dietary methylmercury inhibits mitochondrial energy metabolism in skeletal muscles of the zebra fish (Danio rerio)
    • Cambier S, Benard G, Mesmer-Dudons N, Gonzalez P, Rossignol R, Brethes D, Bourdineaud JP (2009) Atenvironmental doses, dietary methylmercury inhibits mitochondrial energy metabolism in skeletal muscles of the zebra fish (Danio rerio). Int J Biochem Cell Biol 41:791-799
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 791-799
    • Cambier, S.1    Benard, G.2    Mesmer-Dudons, N.3    Gonzalez, P.4    Rossignol, R.5    Brethes, D.6    Bourdineaud, J.P.7
  • 12
    • 75349095407 scopus 로고    scopus 로고
    • Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet
    • Cambier S, Gonzalez P, Durrieu G, Maury-Brachet R, Boudou A, Bourdineaud JP (2010) Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Environ Sci Technol 44:469-475
    • (2010) Environ Sci Technol , vol.44 , pp. 469-475
    • Cambier, S.1    Gonzalez, P.2    Durrieu, G.3    Maury-Brachet, R.4    Boudou, A.5    Bourdineaud, J.P.6
  • 13
    • 0029943154 scopus 로고    scopus 로고
    • Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure
    • Charleston JS, Body RL, Bolender RP, Mottet NK, Vahter ME, Burbacher TM (1996) Changes in the number of astrocytes and microglia in the thalamus of the monkey Macaca fascicularis following long-term subclinical methylmercury exposure. Neurotoxicology 17:127-138
    • (1996) Neurotoxicology , vol.17 , pp. 127-138
    • Charleston, J.S.1    Body, R.L.2    Bolender, R.P.3    Mottet, N.K.4    Vahter, M.E.5    Burbacher, T.M.6
  • 14
    • 0142213730 scopus 로고    scopus 로고
    • The toxicology of mercury-current exposures and clinical manifestations
    • Clarkson TW, Magos L, Myers GJ (2003) The toxicology of mercury-current exposures and clinical manifestations. N Engl J Med 349:1731-1737
    • (2003) N Engl J Med , vol.349 , pp. 1731-1737
    • Clarkson, T.W.1    Magos, L.2    Myers, G.J.3
  • 17
    • 0027517428 scopus 로고
    • Methylmercury alters intrasynaptosomal concentrations of endogenous polyvalent cations
    • Denny MF, Hare MF, Atchison WD (1993) Methylmercury alters intrasynaptosomal concentrations of endogenous polyvalent cations. Toxicol Appl Pharmacol 122:222-232
    • (1993) Toxicol Appl Pharmacol , vol.122 , pp. 222-232
    • Denny, M.F.1    Hare, M.F.2    Atchison, W.D.3
  • 18
    • 34447311633 scopus 로고    scopus 로고
    • Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent
    • Dreiem A, Seegal RF (2007) Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent. Neurotoxicology 28:720-726
    • (2007) Neurotoxicology , vol.28 , pp. 720-726
    • Dreiem, A.1    Seegal, R.F.2
  • 19
    • 24044440959 scopus 로고    scopus 로고
    • The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are agedependent
    • Dreiem A, Gertz CC, Seegal RF (2005) The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are agedependent. Toxicol Sci 87:156-162
    • (2005) Toxicol Sci , vol.87 , pp. 156-162
    • Dreiem, A.1    Gertz, C.C.2    Seegal, R.F.3
  • 20
    • 10044227016 scopus 로고    scopus 로고
    • Goldmining and mercury contamination of the piscivorous fish Hoplias aimara in French Guiana (Amazon basin)
    • Durrieu G, Maury-Brachet R, Boudou A (2005) Goldmining and mercury contamination of the piscivorous fish Hoplias aimara in French Guiana (Amazon basin). Ecotoxicol Environ Saf 60:315-323
    • (2005) Ecotoxicol Environ Saf , vol.60 , pp. 315-323
    • Durrieu, G.1    Maury-Brachet, R.2    Boudou, A.3
  • 21
    • 0033773026 scopus 로고    scopus 로고
    • Minamata disease
    • Eto K (2000) Minamata disease. Neuropathology 20:S14-S19
    • (2000) Neuropathology , vol.20
    • Eto, K.1
  • 22
    • 72049111493 scopus 로고    scopus 로고
    • Apoptogenic and necrogenic effects of mercuric acetate on the chromatin structure of K562 human erythroleukemia cells
    • Farkas E, Ujvarosi K, Nagy G, Posta J, Banfalvi G (2010) Apoptogenic and necrogenic effects of mercuric acetate on the chromatin structure of K562 human erythroleukemia cells. Toxicol In Vitro 24:267-275
    • (2010) Toxicol in Vitro , vol.24 , pp. 267-275
    • Farkas, E.1    Ujvarosi, K.2    Nagy, G.3    Posta, J.4    Banfalvi, G.5
  • 23
    • 13244298893 scopus 로고    scopus 로고
    • Mercury compounds disrupt neuronal glutamate transport in cultured mouse cerebellar granule cells
    • Fonfria E, Vilaro MT, Babot Z, Rodriguez-Farre E, Sunol C (2005) Mercury compounds disrupt neuronal glutamate transport in cultured mouse cerebellar granule cells. J Neurosci Res 79:545-553
    • (2005) J Neurosci Res , vol.79 , pp. 545-553
    • Fonfria, E.1    Vilaro, M.T.2    Babot, Z.3    Rodriguez-Farre, E.4    Sunol, C.5
  • 25
    • 71049144033 scopus 로고    scopus 로고
    • Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain
    • Fujimura M, Usuki F, Sawada M, Takashima A (2009) Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain. Neurotoxicology 30:1000-1007
    • (2009) Neurotoxicology , vol.30 , pp. 1000-1007
    • Fujimura, M.1    Usuki, F.2    Sawada, M.3    Takashima, A.4
  • 26
    • 20044386901 scopus 로고    scopus 로고
    • Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio)
    • Gonzalez P, Dominique Y, Massabuau JC, Boudou A, Bourdineaud JP (2005) Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). Environ Sci Technol 39:3972-3980
    • (2005) Environ Sci Technol , vol.39 , pp. 3972-3980
    • Gonzalez, P.1    Dominique, Y.2    Massabuau, J.C.3    Boudou, A.4    Bourdineaud, J.P.5
  • 27
    • 0029611232 scopus 로고
    • Nifedipine and tetrodotoxin delay the onset of methylmercury-induced increase in [Ca2?]i in NG108-15 cells
    • Hare MF, AtchisonWD (1995a) Nifedipine and tetrodotoxin delay the onset of methylmercury-induced increase in [Ca2?]i in NG108-15 cells. Toxicol Appl Pharmacol 135:299-307
    • (1995) Toxicol Appl Pharmacol , vol.135 , pp. 299-307
    • Hare, M.F.1    Atchison, W.D.2
  • 28
    • 0028969025 scopus 로고
    • Methylmercury mobilizes Ca2? from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells
    • Hare MF, Atchison WD (1995b) Methylmercury mobilizes Ca2? from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells. J Pharmacol Exp Ther 272:1016-1023
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 1016-1023
    • Hare, M.F.1    Atchison, W.D.2
  • 29
    • 0027893207 scopus 로고
    • Methylmercury increases intracellular concentrations of Ca2? and heavy metals in NG108-15 cells
    • Hare MF, McGinnis KM, Atchison WD (1993) Methylmercury increases intracellular concentrations of Ca2? and heavy metals in NG108-15 cells. J Pharmacol Exp Ther 266: 1626-1635
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 1626-1635
    • Hare, M.F.1    McGinnis, K.M.2    Atchison, W.D.3
  • 30
    • 0023143615 scopus 로고
    • Increased free intrasynaptosomal Ca2? by neurotoxic organometals: Distinctive mechanisms
    • Komulainen H, Bondy SC (1987) Increased free intrasynaptosomal Ca2? by neurotoxic organometals: distinctive mechanisms. Toxicol Appl Pharmacol 88:77-86
    • (1987) Toxicol Appl Pharmacol , vol.88 , pp. 77-86
    • Komulainen, H.1    Bondy, S.C.2
  • 31
    • 37249067492 scopus 로고    scopus 로고
    • Expression and water calcium dependence of calcium transporter isoforms in zebrafish gill mitochondrion-rich cells
    • Liao BK, Deng AN, Chen SC, Chou MY, Hwang PP (2007) Expression and water calcium dependence of calcium transporter isoforms in zebrafish gill mitochondrion-rich cells. BMC Genomics 8:354
    • (2007) BMC Genomics , vol.8 , pp. 354
    • Liao, B.K.1    Deng, A.N.2    Chen, S.C.3    Chou, M.Y.4    Hwang, P.P.5
  • 32
    • 0036146443 scopus 로고    scopus 로고
    • Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells
    • Limke TL, Atchison WD (2002) Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells. Toxicol Appl Pharmacol 178:52-61
    • (2002) Toxicol Appl Pharmacol , vol.178 , pp. 52-61
    • Limke, T.L.1    Atchison, W.D.2
  • 33
    • 0037369885 scopus 로고    scopus 로고
    • Evidence for interactions between intracellular calcium stores during methylmercury-induced intracellular calcium dysregulation in rat cerebellar granule neurons
    • Limke TL, Otero-Montanez JK, Atchison WD (2003) Evidence for interactions between intracellular calcium stores during methylmercury-induced intracellular calcium dysregulation in rat cerebellar granule neurons. J Pharmacol Exp Ther 304:949-958
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 949-958
    • Limke, T.L.1    Otero-Montanez, J.K.2    Atchison, W.D.3
  • 34
    • 3242812890 scopus 로고    scopus 로고
    • Methylmercury causes Ca2? dysregulation and neuronal death in rat cerebellar granule cells through an M3 muscarinic receptorlinked pathway
    • Limke TL, Bearss JJ, Atchison WD (2004a) Methylmercury causes Ca2? dysregulation and neuronal death in rat cerebellar granule cells through an M3 muscarinic receptorlinked pathway. Toxicol Sci 80:60-68
    • (2004) Toxicol Sci , vol.80 , pp. 60-68
    • Limke, T.L.1    Bearss, J.J.2    Atchison, W.D.3
  • 35
    • 3543035275 scopus 로고    scopus 로고
    • Disruption of intraneuronal divalent cation regulation by methylmercury: Are specific targets involved in altered neuronal development and cytotoxicity in methylmercury poisoning?
    • Limke TL, Heidemann SR, Atchison WD (2004b) Disruption of intraneuronal divalent cation regulation by methylmercury: are specific targets involved in altered neuronal development and cytotoxicity in methylmercury poisoning? Neurotoxicology 25:741-760
    • (2004) Neurotoxicology , vol.25 , pp. 741-760
    • Limke, T.L.1    Heidemann, S.R.2    Atchison, W.D.3
  • 36
    • 67349095334 scopus 로고    scopus 로고
    • Effects of postnatal exposure to methylmercury on spatial learning and memory and brain NMDA receptor mRNA expression in rats
    • Liu W, Wang X, Zhang R, Zhou Y (2009) Effects of postnatal exposure to methylmercury on spatial learning and memory and brain NMDA receptor mRNA expression in rats. Toxicol Lett 188:230-235
    • (2009) Toxicol Lett , vol.188 , pp. 230-235
    • Liu, W.1    Wang, X.2    Zhang, R.3    Zhou, Y.4
  • 37
    • 0031851557 scopus 로고    scopus 로고
    • The fate of organic xenobiotics in aquatic ecosystems: Quantitative and qualitative differences in biotransformation by invertebrates and fish
    • Livingstone DR (1998) The fate of organic xenobiotics in aquatic ecosystems: quantitative and qualitative differences in biotransformation by invertebrates and fish. Comp Biochem Physiol A 120:43-49
    • (1998) Comp Biochem Physiol A , vol.120 , pp. 43-49
    • Livingstone, D.R.1
  • 39
    • 0031309785 scopus 로고    scopus 로고
    • Pathways mediating Ca2? entry in rat cerebellar granule cells following in vitro exposure to methyl mercury
    • Marty MS, Atchison WD (1997) Pathways mediating Ca2? entry in rat cerebellar granule cells following in vitro exposure to methyl mercury. Toxicol Appl Pharmacol 147:319-330
    • (1997) Toxicol Appl Pharmacol , vol.147 , pp. 319-330
    • Marty, M.S.1    Atchison, W.D.2
  • 40
    • 0034426260 scopus 로고    scopus 로고
    • Widespread calcium deposits, as detected using the alizarin red S technique, in the nervous system of rats treated with dimethyl mercury
    • Mori F, Tanji K, Wakabayashi K (2000) Widespread calcium deposits, as detected using the alizarin red S technique, in the nervous system of rats treated with dimethyl mercury. Neuropathology 20:210-215
    • (2000) Neuropathology , vol.20 , pp. 210-215
    • Mori, F.1    Tanji, K.2    Wakabayashi, K.3
  • 41
    • 35748959328 scopus 로고    scopus 로고
    • Comparative study of activities in reactive oxygen species production/defense system in mitochondria of rat brain and liver, and their susceptibility to methylmercury toxicity
    • Mori N, Yasutake A, Hirayama K (2007) Comparative study of activities in reactive oxygen species production/defense system in mitochondria of rat brain and liver, and their susceptibility to methylmercury toxicity. Arch Toxicol 81:769-776
    • (2007) Arch Toxicol , vol.81 , pp. 769-776
    • Mori, N.1    Yasutake, A.2    Hirayama, K.3
  • 42
    • 19444378229 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity
    • O'Callaghan JP, Sriram K (2005) Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity. Expert Opin Drug Saf 4:433-442
    • (2005) Expert Opin Drug Saf , vol.4 , pp. 433-442
    • O'callaghan, J.P.1    Sriram, K.2
  • 43
    • 0013986322 scopus 로고
    • Neuropathological studies on organic mercury poisoning with special reference to the staining and distribution of mercury granules
    • Oyake Y, Tanaka M, Kubo H, Chichibu M (1966) Neuropathological studies on organic mercury poisoning with special reference to the staining and distribution of mercury granules. Shinkei Kenkyu No Shimpo 10:744-750
    • (1966) Shinkei Kenkyu No Shimpo , vol.10 , pp. 744-750
    • Oyake, Y.1    Tanaka, M.2    Kubo, H.3    Chichibu, M.4
  • 44
    • 0030010607 scopus 로고    scopus 로고
    • Methylmercuryinduced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists
    • Park ST, Lim KT, Chung YT, Kim SU (1996) Methylmercuryinduced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists. Neurotoxicology 17:37-45
    • (1996) Neurotoxicology , vol.17 , pp. 37-45
    • Park, S.T.1    Lim, K.T.2    Chung, Y.T.3    Kim, S.U.4
  • 46
    • 0027194712 scopus 로고
    • Methyl mercury increases intracellular Ca2? and inositol phosphate levels in cultured cerebellar granule neurons
    • Sarafian TA (1993) Methyl mercury increases intracellular Ca2? and inositol phosphate levels in cultured cerebellar granule neurons. J Neurochem 61:648-657
    • (1993) J Neurochem , vol.61 , pp. 648-657
    • Sarafian, T.A.1
  • 47
    • 66149090319 scopus 로고    scopus 로고
    • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish
    • Timme-Laragy AR, Van Tiem LA, Linney EA, Di Giulio RT (2009) Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. Toxicol Sci 109:217-227
    • (2009) Toxicol Sci , vol.109 , pp. 217-227
    • Timme-Laragy, A.R.1    Van Tiem, L.A.2    Linney, E.A.3    Di Giulio, R.T.4
  • 48
    • 0031777493 scopus 로고    scopus 로고
    • The effect of methylmercury on skeletal muscle in the rat: A histopathological study
    • Usuki F, Yasutake A, Matsumoto M, Umehara F, Higuchi I (1998) The effect of methylmercury on skeletal muscle in the rat: a histopathological study. Toxicol Lett 94:227-232
    • (1998) Toxicol Lett , vol.94 , pp. 227-232
    • Usuki, F.1    Yasutake, A.2    Matsumoto, M.3    Umehara, F.4    Higuchi, I.5
  • 49
    • 79953208992 scopus 로고    scopus 로고
    • Posttranscriptional defects of antioxidant selenoenzymes causes oxidative stress under methylmercury exposure
    • Usuki F, Yamashita A, Fujimura M (2010) Posttranscriptional defects of antioxidant selenoenzymes causes oxidative stress under methylmercury exposure. J Biol Chem 286:6641-6649
    • (2010) J Biol Chem , vol.286 , pp. 6641-6649
    • Usuki, F.1    Yamashita, A.2    Fujimura, M.3
  • 50
    • 85050650004 scopus 로고    scopus 로고
    • Ecotoxicology of mercury
    • Hoffman DJ, Rattner BA, Burton GA, Cairns J . Lewis Publishers, Boca Raton, FL
    • Wiener JG, Krabbenhoft DP, Heinz GH, Scheuhammer AM (2003) Ecotoxicology of mercury. In: Hoffman DJ, Rattner BA, Burton GA, Cairns J (eds) Handbook of ecotoxicology. Lewis Publishers, Boca Raton, FL, pp 409-463
    • (2003) Handbook of Ecotoxicology , pp. 409-463
    • Wiener, J.G.1    Krabbenhoft, D.P.2    Heinz, G.H.3    Scheuhammer, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.