메뉴 건너뛰기




Volumn 59, Issue 1, 2012, Pages 69-76

Cell cycle-specific function of Ikaros in human leukemia

Author keywords

Casein kinase 2; Cell cycle; Ikaros; Isoforms; Leukemia; Phosphorylation

Indexed keywords

CASEIN KINASE II; GENOMIC DNA; IKAROS TRANSCRIPTION FACTOR; ISOPROTEIN; PHOSPHOPEPTIDE;

EID: 84861208113     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23406     Document Type: Article
Times cited : (19)

References (48)
  • 1
    • 0033231420 scopus 로고    scopus 로고
    • Defects in hemopoietic stem cell activity in Ikaros mutant mice
    • Nichogiannopoulou A, Trevisan M, Neben S, et al. Defects in hemopoietic stem cell activity in Ikaros mutant mice. J Exp Med 1999; 190: 1201-1214.
    • (1999) J Exp Med , vol.190 , pp. 1201-1214
    • Nichogiannopoulou, A.1    Trevisan, M.2    Neben, S.3
  • 2
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang JH, Nichogiannopoulou A, Wu L, et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996; 5: 537-549.
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1    Nichogiannopoulou, A.2    Wu, L.3
  • 3
    • 0037154228 scopus 로고    scopus 로고
    • Multiple hematopoietic defects and delayed globin switching in Ikaros null mice
    • Lopez RA, Schoetz S, DeAngelis K, et al. Multiple hematopoietic defects and delayed globin switching in Ikaros null mice. Proc Natl Acad Sci U S A 2002; 99: 602-607.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 602-607
    • Lopez, R.A.1    Schoetz, S.2    DeAngelis, K.3
  • 4
    • 0038106526 scopus 로고    scopus 로고
    • Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
    • Papathanasiou P, Perkins AC, Cobb BS, et al. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity 2003; 19: 131-144.
    • (2003) Immunity , vol.19 , pp. 131-144
    • Papathanasiou, P.1    Perkins, A.C.2    Cobb, B.S.3
  • 5
    • 0037443458 scopus 로고    scopus 로고
    • Ikaros regulates neutrophil differentiation
    • Dumortier A, Kirstetter P, Kastner P, et al. Ikaros regulates neutrophil differentiation. Blood 2003; 101: 2219-2226.
    • (2003) Blood , vol.101 , pp. 2219-2226
    • Dumortier, A.1    Kirstetter, P.2    Kastner, P.3
  • 6
    • 0028866897 scopus 로고
    • A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma
    • Winandy S, Wu P, Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 1995; 83: 289-299.
    • (1995) Cell , vol.83 , pp. 289-299
    • Winandy, S.1    Wu, P.2    Georgopoulos, K.3
  • 7
    • 0033581933 scopus 로고    scopus 로고
    • Homozygous deletions and point mutations of the Ikaros gene in gamma- ray-induced mouse thymic lymphomas
    • Okano H, Saito Y, Miyazawa T, et al. Homozygous deletions and point mutations of the Ikaros gene in gamma- ray-induced mouse thymic lymphomas. Oncogene 1999; 18: 6677-6683.
    • (1999) Oncogene , vol.18 , pp. 6677-6683
    • Okano, H.1    Saito, Y.2    Miyazawa, T.3
  • 8
    • 0038356318 scopus 로고    scopus 로고
    • Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies
    • Rebollo A, Schmitt C. Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies. Immunol Cell Biol 2003; 81: 171-175.
    • (2003) Immunol Cell Biol , vol.81 , pp. 171-175
    • Rebollo, A.1    Schmitt, C.2
  • 9
    • 34047251670 scopus 로고    scopus 로고
    • Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms
    • Ronni T, Payne KJ, Ho S, et al. Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms. J Biol Chem 2007; 282: 2538-2547.
    • (2007) J Biol Chem , vol.282 , pp. 2538-2547
    • Ronni, T.1    Payne, K.J.2    Ho, S.3
  • 10
    • 0035881050 scopus 로고    scopus 로고
    • Cutting edge: Predominant expression of a novel Ikaros isoform in normal human hemopoiesis
    • Payne KJ, Nicolas JH, Zhu JY, et al. Cutting edge: Predominant expression of a novel Ikaros isoform in normal human hemopoiesis. J Immunol 2001; 167: 1867-1870.
    • (2001) J Immunol , vol.167 , pp. 1867-1870
    • Payne, K.J.1    Nicolas, J.H.2    Zhu, J.Y.3
  • 11
    • 0037443411 scopus 로고    scopus 로고
    • Ikaros isoform x is selectively expressed in myeloid differentiation
    • Payne KJ, Huang G, Sahakian E, et al. Ikaros isoform x is selectively expressed in myeloid differentiation. J Immunol 2003; 170: 3091-3098.
    • (2003) J Immunol , vol.170 , pp. 3091-3098
    • Payne, K.J.1    Huang, G.2    Sahakian, E.3
  • 12
    • 63849152625 scopus 로고    scopus 로고
    • Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing
    • Kim JH, Ebersole T, Kouprina N, et al. Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res 2009; 19: 533-544.
    • (2009) Genome Res , vol.19 , pp. 533-544
    • Kim, J.H.1    Ebersole, T.2    Kouprina, N.3
  • 13
    • 0036897132 scopus 로고    scopus 로고
    • A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains
    • Dovat S, Ronni T, Russell D, et al. A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains. Genes Dev 2002; 16: 2985-2990.
    • (2002) Genes Dev , vol.16 , pp. 2985-2990
    • Dovat, S.1    Ronni, T.2    Russell, D.3
  • 14
    • 84861212482 scopus 로고    scopus 로고
    • Regulator of myeloid differentiation and function: The secret life of Ikaros
    • Francis OL, Payne JL, Su RJ, et al. Regulator of myeloid differentiation and function: The secret life of Ikaros. World J Biol Chem 2011; 2: 119-125.
    • (2011) World J Biol Chem , vol.2 , pp. 119-125
    • Francis, O.L.1    Payne, J.L.2    Su, R.J.3
  • 16
    • 0029831978 scopus 로고    scopus 로고
    • Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development
    • Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. Embo J 1996; 15: 5358-5369.
    • (1996) Embo J , vol.15 , pp. 5358-5369
    • Sun, L.1    Liu, A.2    Georgopoulos, K.3
  • 17
    • 0031437119 scopus 로고    scopus 로고
    • Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
    • Brown KE, Guest SS, Smale ST, et al. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 1997; 91: 845-854.
    • (1997) Cell , vol.91 , pp. 845-854
    • Brown, K.E.1    Guest, S.S.2    Smale, S.T.3
  • 19
    • 43749107094 scopus 로고    scopus 로고
    • Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation
    • Gurel Z, Ronni T, Ho S, et al. Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation. J Biol Chem 2008; 283: 8291-8300.
    • (2008) J Biol Chem , vol.283 , pp. 8291-8300
    • Gurel, Z.1    Ronni, T.2    Ho, S.3
  • 20
    • 67649405070 scopus 로고    scopus 로고
    • Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1
    • Popescu M, Gurel Z, Ronni T, et al. Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1. J Biol Chem 2009; 284: 13869-13880.
    • (2009) J Biol Chem , vol.284 , pp. 13869-13880
    • Popescu, M.1    Gurel, Z.2    Ronni, T.3
  • 21
    • 84860241029 scopus 로고    scopus 로고
    • Regulation of Ikaros function by casein kinase 2 and protein phosphatase 1
    • Song C, Li Z, Erbe AK, et al. Regulation of Ikaros function by casein kinase 2 and protein phosphatase 1. World J Biol Chem 2011; 2: 126-131.
    • (2011) World J Biol Chem , vol.2 , pp. 126-131
    • Song, C.1    Li, Z.2    Erbe, A.K.3
  • 22
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, Goorha S, Radtke I, et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 2007; 446: 758-764.
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1    Goorha, S.2    Radtke, I.3
  • 23
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 2008; 453: 110-114.
    • (2008) Nature , vol.453 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3
  • 24
    • 34249733805 scopus 로고    scopus 로고
    • High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
    • Kuiper RP, Schoenmakers EF, van Reijmersdal SV, et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia 2007; 21: 1258-1266.
    • (2007) Leukemia , vol.21 , pp. 1258-1266
    • Kuiper, R.P.1    Schoenmakers, E.F.2    van Reijmersdal, S.V.3
  • 25
    • 77049110561 scopus 로고    scopus 로고
    • Genetic inactivation of Ikaros is a rare event in human T-ALL
    • Marcais A, Jeannet R, Hernandez L, et al. Genetic inactivation of Ikaros is a rare event in human T-ALL. Leuk Res 2010; 34: 426-429.
    • (2010) Leuk Res , vol.34 , pp. 426-429
    • Marcais, A.1    Jeannet, R.2    Hernandez, L.3
  • 26
    • 76749127429 scopus 로고    scopus 로고
    • Tumor suppression in T cell leukemia-the role of Ikaros
    • Dovat S, Payne KJ. Tumor suppression in T cell leukemia-the role of Ikaros. Leuk Res 2010; 34: 416-417.
    • (2010) Leuk Res , vol.34 , pp. 416-417
    • Dovat, S.1    Payne, K.J.2
  • 27
    • 79952576445 scopus 로고    scopus 로고
    • Improving outcomes for high-risk ALL: Translating new discoveries into clinical care
    • Hunger SP, Raetz EA, Loh ML, et al. Improving outcomes for high-risk ALL: Translating new discoveries into clinical care. Pediatr Blood Cancer 2011; 56: 984-993.
    • (2011) Pediatr Blood Cancer , vol.56 , pp. 984-993
    • Hunger, S.P.1    Raetz, E.A.2    Loh, M.L.3
  • 28
    • 77955985136 scopus 로고    scopus 로고
    • Genetic variation and the risk of acute lymphoblastic leukemia
    • Mullighan CG. Genetic variation and the risk of acute lymphoblastic leukemia. Leuk Res 2010; 34: 1269-1270.
    • (2010) Leuk Res , vol.34 , pp. 1269-1270
    • Mullighan, C.G.1
  • 29
    • 79551699535 scopus 로고    scopus 로고
    • New strategies in acute lymphoblastic leukemia: Translating advances in genomics into clinical practice
    • Mullighan CG. New strategies in acute lymphoblastic leukemia: Translating advances in genomics into clinical practice. Clin Cancer Res 2011; 17: 396-400.
    • (2011) Clin Cancer Res , vol.17 , pp. 396-400
    • Mullighan, C.G.1
  • 30
    • 0033582324 scopus 로고    scopus 로고
    • Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia
    • Sun L, Heerema N, Crotty L, et al. Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 1999; 96: 680-685.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 680-685
    • Sun, L.1    Heerema, N.2    Crotty, L.3
  • 31
    • 0033870658 scopus 로고    scopus 로고
    • Dominant negative isoform of the Ikaros gene in patients with adult B- cell acute lymphoblastic leukemia
    • Nakase K, Ishimaru F, Avitahl N, et al. Dominant negative isoform of the Ikaros gene in patients with adult B- cell acute lymphoblastic leukemia. Cancer Res 2000; 60: 4062-4065.
    • (2000) Cancer Res , vol.60 , pp. 4062-4065
    • Nakase, K.1    Ishimaru, F.2    Avitahl, N.3
  • 32
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
    • Mullighan CG, Su X, Zhang J, et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 2009; 360: 470-480.
    • (2009) N Engl J Med , vol.360 , pp. 470-480
    • Mullighan, C.G.1    Su, X.2    Zhang, J.3
  • 33
    • 84859440906 scopus 로고    scopus 로고
    • Role of Ikaros in T-cell acute lymphoblastic leukemia
    • Kastner P, Chan S. Role of Ikaros in T-cell acute lymphoblastic leukemia. World J Biol Chem 2011; 2: 108-114.
    • (2011) World J Biol Chem , vol.2 , pp. 108-114
    • Kastner, P.1    Chan, S.2
  • 34
    • 84855227729 scopus 로고    scopus 로고
    • Ikaros, CK2 kinase, and the road to leukemia
    • Epub ahead of print].
    • Dovat S, Song C, Payne KJ, et al. Ikaros, CK2 kinase, and the road to leukemia. Mol Cell Biochem 2011; [Epub ahead of print].
    • (2011) Mol Cell Biochem
    • Dovat, S.1    Song, C.2    Payne, K.J.3
  • 35
    • 0028152483 scopus 로고
    • The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
    • Hahm K, Ernst P, Lo K, et al. The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Mol Cell Biol 1994; 14: 7111-7123.
    • (1994) Mol Cell Biol , vol.14 , pp. 7111-7123
    • Hahm, K.1    Ernst, P.2    Lo, K.3
  • 36
    • 84856909174 scopus 로고    scopus 로고
    • Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the ikaros gene
    • Epub ahead of print].
    • Goldman FD, Gurel Z, Al-Zubeidi D, et al. Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the ikaros gene. Pediatr Blood Cancer 2011; [Epub ahead of print].
    • (2011) Pediatr Blood Cancer
    • Goldman, F.D.1    Gurel, Z.2    Al-Zubeidi, D.3
  • 37
    • 0032567347 scopus 로고    scopus 로고
    • Down-regulation of human granzyme B expression by glucocorticoids. Dexamethasone inhibits binding to the Ikaros and AP-1 regulatory elements of the granzyme B promoter
    • Wargnier A, Lafaurie C, Legros-Maida S, et al. Down-regulation of human granzyme B expression by glucocorticoids. Dexamethasone inhibits binding to the Ikaros and AP-1 regulatory elements of the granzyme B promoter. J Biol Chem 1998; 273: 35326-35331.
    • (1998) J Biol Chem , vol.273 , pp. 35326-35331
    • Wargnier, A.1    Lafaurie, C.2    Legros-Maida, S.3
  • 38
    • 0034711234 scopus 로고    scopus 로고
    • Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences
    • Ghanshani S, Wulff H, Miller MJ, et al. Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. J Biol Chem 2000; 275: 37137-37149.
    • (2000) J Biol Chem , vol.275 , pp. 37137-37149
    • Ghanshani, S.1    Wulff, H.2    Miller, M.J.3
  • 39
    • 27644467061 scopus 로고    scopus 로고
    • Targeting CK2 for cancer therapy
    • Ahmad KA, Wang G, Slaton J, et al. Targeting CK2 for cancer therapy. Anticancer Drugs 2005; 16: 1037-1043.
    • (2005) Anticancer Drugs , vol.16 , pp. 1037-1043
    • Ahmad, K.A.1    Wang, G.2    Slaton, J.3
  • 40
    • 33847361829 scopus 로고    scopus 로고
    • Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia
    • Kim JS, Eom JI, Cheong JW, et al. Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia. Clin Cancer Res 2007; 13: 1019-1028.
    • (2007) Clin Cancer Res , vol.13 , pp. 1019-1028
    • Kim, J.S.1    Eom, J.I.2    Cheong, J.W.3
  • 41
    • 0037043777 scopus 로고    scopus 로고
    • Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis
    • Channavajhala P, Seldin DC. Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene 2002; 21: 5280-5288.
    • (2002) Oncogene , vol.21 , pp. 5280-5288
    • Channavajhala, P.1    Seldin, D.C.2
  • 42
    • 0029815976 scopus 로고    scopus 로고
    • Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha
    • Kelliher MA, Seldin DC, Leder P. Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha. Embo J 1996; 15: 5160-5166.
    • (1996) Embo J , vol.15 , pp. 5160-5166
    • Kelliher, M.A.1    Seldin, D.C.2    Leder, P.3
  • 43
    • 0028985936 scopus 로고
    • Casein kinase II alpha transgene-induced murine lymphoma: Relation to theileriosis in cattle
    • Seldin DC, Leder P. Casein kinase II alpha transgene-induced murine lymphoma: Relation to theileriosis in cattle. Science 1995; 267: 894-897.
    • (1995) Science , vol.267 , pp. 894-897
    • Seldin, D.C.1    Leder, P.2
  • 44
    • 77957961828 scopus 로고    scopus 로고
    • Targeting CK2 overexpression and hyperactivation as a novel therapeutic tool in chronic lymphocytic leukemia
    • Martins LR, Lucio P, Silva MC, et al. Targeting CK2 overexpression and hyperactivation as a novel therapeutic tool in chronic lymphocytic leukemia. Blood 2010; 116: 2724-2731.
    • (2010) Blood , vol.116 , pp. 2724-2731
    • Martins, L.R.1    Lucio, P.2    Silva, M.C.3
  • 45
    • 12144291320 scopus 로고    scopus 로고
    • Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition
    • Gomez-del Arco P, Maki K, Georgopoulos K. Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition. Mol Cell Biol 2004; 24: 2797-2807.
    • (2004) Mol Cell Biol , vol.24 , pp. 2797-2807
    • Gomez-del Arco, P.1    Maki, K.2    Georgopoulos, K.3
  • 46
    • 0032761116 scopus 로고    scopus 로고
    • Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia
    • Sun L, Goodman PA, Wood CM, et al. Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia. J Clin Oncol 1999; 17: 3753-3766.
    • (1999) J Clin Oncol , vol.17 , pp. 3753-3766
    • Sun, L.1    Goodman, P.A.2    Wood, C.M.3
  • 47
    • 0033849663 scopus 로고    scopus 로고
    • Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
    • Cobb BS, Morales-Alcelay S, Kleiger G, et al. Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes and Development 2000; 14: 2146-2160.
    • (2000) Genes and Development , vol.14 , pp. 2146-2160
    • Cobb, B.S.1    Morales-Alcelay, S.2    Kleiger, G.3
  • 48
    • 14044269513 scopus 로고    scopus 로고
    • Ikaros induces quiescence and T-cell differentiation in a leukemia cell line
    • Kathrein KL, Lorenz R, Innes AM, et al. Ikaros induces quiescence and T-cell differentiation in a leukemia cell line. Mol Cell Biol 2005; 25: 1645-1654.
    • (2005) Mol Cell Biol , vol.25 , pp. 1645-1654
    • Kathrein, K.L.1    Lorenz, R.2    Innes, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.