A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains

Genes and Development

Volumn 16, Issue 23, 2002, Pages 2985-2990

  Dovat, Sinisa ^a,b   Ronni, Tapani ^a   Russell, Dana ^a   Ferrini, Roger ^a   Cobb, Bradley S ^a   Smale, Stephen T ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell cycle; Ikaros; Mitosis; Phosphorylation; Zinc finger

Indexed keywords

DNA; IKAROS TRANSCRIPTION FACTOR; NUCLEAR PROTEIN; POLYPEPTIDE; PROTEOME; TRANSCRIPTION FACTOR C2H2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIVISION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA BINDING; GENETIC CONSERVATION; GENETIC LINKAGE; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE; DNA-BINDING PROTEINS; IKAROS TRANSCRIPTION FACTOR; MICE; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS; ZINC FINGERS;

ANIMALIA;

EID: 0036897132     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1040502     Document Type: Article

References (40)

1. Aagaard, L., Schmid, M., Warburton, P., and Jenuwein, T. 2000. Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres. J. Cell Sci. 113: 817-829.
2. Akoulitchev, S. and Reinberg, D. 1998. The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7. Genes & Dev. 12: 3541-3550.
3. Bellier, S., Dubois, M.F., Nishida, E., Almouzni, G., and Bensaude, O. 1997. Phosphorylation of the RNA polymerase II largest subunit during Xenopus laevis oocyte maturation. Mol. Cell Biol. 17: 1434-1440.
4. Bowers, P.M., Schaufler, L.E., and Klevit, R.E. 1999. A folding transition and novel zinc finger accessory domain in the transcription factor ADR1. Nat. Struct. Biol. 6: 478-485.
5. Brown, K.E., Guest, S.S., Smale, S.T., Hahm, K., Merkenschlager, M., and Fisher, A.G. 1997. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 91: 845-854.
6. Brown, K.E., Baxter, J., Graf, D., Merkenschlager, M., and Fisher, A.G. 1999. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell 3: 207-217.
7. Buchenau, P., Hodgson, J., Strutt, H., and Arndt-Jovin, D.J. 1998. The distribution of polycomb-group proteins during cell division and development in Drosophila embryos: Impact on models for silencing. J. Cell Biol. 141: 469-481.
8. Caelles, C., Hennemann, H., and Karin, M. 1995. M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding. Mol Cell. Biol. 15: 6694-6701.
9. Choo, Y. and Klug, A. 1993. A role in DNA binding for the linker sequences of the first three fingers of TFIIIA. Nucleic Acids Res. 21: 3341-3346.
10. Clemens, K.R., Zhang, P., Liao, X., McBryant, S.J., Wright, P.E., and Gottesfeld, J.M. 1994. Relative contributions of the zinc fingers of transcription factor IIIA to the energetics of DNA binding. J. Mol Biol. 244: 23-35.
11. Cobb, B.S., Morales-Alcelay, S., Kleiger, G., Brown, K.E., Fisher, A.G., and Smale, S.T. 2000. Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes & Dev. 14: 2146-2160.
12. Cortes, M., Wong, E., Koipally, J., and Georgopoulos, K. 1999. Control of lymphocyte development by the Ikaros gene family. Curr. Opin. Immunol. 11: 167-171.
13. Dietzel, S., Niemann, H., Bruckner, B., Maurange, C., and Paro, R. 1999. The nuclear distribution of Polycomb during Drosophila melanogaster development shown with a GFP fusion protein. Chromosoma 108: 83-94.
14. Georgopoulos, K. 2002. Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nat. Rev. Immunol. 2: 162-174.
15. Gottesfeld, J.M. and Forbes, D.J. 1997. Mitotic repression of the transcriptional machinery. Trends Biochem. Sci. 22: 197-202.
16. Groves, T., Katis, P., Madden, Z., Manickam, K., Ramsden, D., Wu, G., and Guidos, C.J. 1995. In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement. J. Immunol. 154: 5011-5022.
17. Hahm, K., Ernst, P., Lo, K., Kim, G.S., Turck, C., and Smale, S.T. 1994. The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Mol. Cell. Biol. 14: 7111-7123.
18. Hawley, R.G., Lieu, F.H., Fong, A.Z., and Hawley, T.S. 1994. Versatile retroviral vectors for potential use in gene therapy. Gene Therapy 1: 136-138.
19. Kadonaga, J.T., Carner, K.R., Masiarz, F.R., and Tjian, R. 1987. Isolation of cDNA encoding transcription factor Spl and functional analysis of the DNA binding domain. Cell 51: 1079-1090
20. Kim, J., Sif, S., Jones, B., Jackson, A., Koipally, J., Heller, E., Winandy, S., Viel, A., Sawyer, A., Ikeda, T., et al. 1999. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10: 345-355.
21. 2 zinc fingers. J. Mol. Biol. 295: 719-727.
22. Lander, E.S., Linton, M., Birren, B., Nusbaum, C., Zody, M.C., Baldwin, J., Devan, K., Dewar, K., Doyle, M., Pitzhugh, W., et al. 2001. Initial sequencing and analysis of the human genome. Nature 409: 860-921.
23. Long, J.J., Leresche, R.W., Kriwaski, R.W., and Gottesfeld, J.M. 1998. Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis. Mol. Cell. Biol. 18: 1467-1476.
24. Martínez-Balbás, M.A., Dey, A., Rabindran, S.K., Ozato, K., and Wu, C. 1995. Displacement of sequence-specific transcription factors from mitotic chromatin. Cell 83: 29-38.
25. Minc, E., Allory, Y., Worman, H.J., Courvalin, J.C., and Buendia, B. 1999. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. Chromosoma 108: 220-234.
26. Molnar, A. and Georgopoulos, K. 1994. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Mol. Cell. Biol 14: 8292-8303.
27. Prescott, D.M. and Bender, M.A. 1962. Synthesis of RNA and protein during mitosis in mammalian tissue culture cells. Exp. Cell Res. 26: 260-268.
28. Segil, N., Roberts, S.B., and Heintz, N. 1991. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science 254: 1814-1816.
29. Segil, N., Guermah, M., Hoffmann, A., Roeder, R.G., and Heintz, N. 1996. Mitotic regulation of TFIID inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Dev. 10: 2389-2400.
30. Sif, S., Stukenberg, P.T., Kirschner, M.W., and Kingston, R.E. 1998. Mitotic inactivation of a human SWI/SNF chromatin remodeling complex. Genes & Dev. 12: 2842-2851.
31. Smale, S.T. and Fisher, A.G. 2002. Chromatin structure and gene activation in the immune system. Annu. Rev. Immunol. 20: 427-462.
32. Thukral, S.K., Morrison, M.L., and Young, E.T. 1991. Alanine scanning site-directed mutagenesis of the zinc fingers of transcription factor ADR1: Residues that contact DNA and that transactivate. Proc. Natl. Acad. Sci. 88: 9188-9192.
33. + thymocytes by Ikaros proteins in direct competition with an Ets activator. Genes & Dev. 15: 1817-1832.
34. Tupler, R., Perini, G., and Green, M.R. 2001. Expressing the human genome. Nature 409: 832-833.
35. Voncken, J.W., Schweizer, D., Aagaard, L., Sattler, L., Jantsch, M.F., and van Lohuizen, M. 1999. Chromatin-association of the Polycomb group protein BMII is cell cycle-regulated and correlates with its phosphorylation status. J. Cell Sci. 112: 4627-4639.
36. Wendell, K.L., Wilson, L., and Jordan, M.A. 1993. Mitotic block in HeLa cells by vinblastine: Ultrastructural changes in kinetochore-microtubule attachment and in centrosomes. J. Cell. Sci. 104: 261-274.
37. Wilson, T.E., Day, M.L., Pexton, T., Padgett, K.A., Johnston, M., and Milbrandt, J. 1992. In vivo mutational analysis of the NGFI-A zinc fingers. J. Biol. Chem. 267: 3718-3724.
38. Wolfe, S.A., Nekludova, L., and Pabo, C.O. 2000. DNA recognition by Cys2His2 zinc finger proteins. Annu. Rev. Biophys. Biomol. Struct. 29:183-212.
39. Wuttke, D.S., Foster, M.P., Case, D.A., Gottesfeld, J.M., and Wright, P.E. 1997. Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: Determinants of affinity and sequence specificity. J. Mol. Biol. 273: 183-206.
40. Yamamoto, Y., Girard, F., Bello, B., Affolter, M., and Gehring, W.J. 1997. The cramped gene of Drosophila is a member of the Polycomb-group, and interacts with mus209, the gene encoding Proliferating Cell Nuclear Antigen. Development 124: 3385-3394.