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Volumn 20, Issue 11, 2012, Pages 3615-3621
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Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives
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Author keywords
2 (1,3,4 Oxadiazol 2 ylthio) 1 phenylethanone derivatives; A431; Focal adhesion kinase; MCF 7; Molecular docking; Skin cancer
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Indexed keywords
1 (4 BROMOPHENYL) 2 [5 (2 AMINOPYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 (4 BROMOPHENYL) ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (2 CHLOROPYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (2 FLUOROPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (2 HYDROXY 4 METHYLPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (2 METHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (3,5 DIMETHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (4 TERT BUTYLPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (NAPHTHALEN 1 YL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 (PYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 (4 BROMOPHENYL) 2 [5 [4 (DIMETHYLAMINO)PHENYL] 1,3,4 OXADIAZOL 2 YLTHIO] ETHANONE;
1 PHENYL 2 [2 (PYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO]ETHANONE;
2 (1,3,4 OXADIAZOL 2 YLTHIO) 1 PHENYLETHANONE DERIVATIVE;
2 [5 (2 AMINOPYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 CHLOROPYRIDIN 4 YL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 ETHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 FLUOROPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 HYDROXY 4 METHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 HYDROXY 4 METHYLPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (2 METHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (3,5 DIMETHOXYPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (4 TERT BUTYLPHENYL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 (NAPHTHALEN 1 YL) 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
2 [5 [4 (DIMETHYLAMINO)PHENYL] 1,3,4 OXADIAZOL 2 YLTHIO] 1 PHENYLETHANONE;
FOCAL ADHESION KINASE INHIBITOR;
UNCLASSIFIED DRUG;
ARTICLE;
BIOASSAY;
BIOLOGICAL ACTIVITY;
CELL STRAIN MCF 7;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
IC 50;
MOLECULAR DOCKING;
MOLECULAR MODEL;
SIMULATION;
ACETOPHENONES;
ANIMALS;
APOPTOSIS;
CATALYTIC DOMAIN;
CATTLE;
CELL LINE, TUMOR;
DRUG SCREENING ASSAYS, ANTITUMOR;
FOCAL ADHESION PROTEIN-TYROSINE KINASES;
HUMANS;
INHIBITORY CONCENTRATION 50;
MODELS, MOLECULAR;
PROTEIN KINASE INHIBITORS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84861188782
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.03.061 Document Type: Article |
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Times cited : (39)
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References (24)
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