Development of a new enzyme-responsive self-immolative spacer conjugate applicable to the controlled drug release

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 11, 2012, Pages 3465-3469

  Jin, Hui Juan ^a   Lu, Jing ^a   Wu, Xue ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Conjugate; Controlled release; Drug release; Enzyme responsive spacer; Self immolative spacer

Indexed keywords

2,5 PIPERAZINEDIONE DERIVATIVE; 7 AMINO 4 TRIFLUOROMETHYLCOUMARIN; COUMARIN DERIVATIVE; CYSTEINE; PIPERAZINE DERIVATIVE; SOLUBILIZER; UNCLASSIFIED DRUG;

ARTICLE; CONJUGATE; CONTROLLED DRUG RELEASE; CYCLIZATION; ENZYME ACTIVITY; ENZYME RESPONSIVE SELF IMMOLATIVE SPACER CONJUGATE; ENZYME SUBSTRATE; SYNTHESIS;

COUMARINS; CYCLIZATION; CYSTEINE; DELAYED-ACTION PREPARATIONS; DRUG DESIGN; ENZYMES; FLUORESCENT DYES; MOLECULAR STRUCTURE; PENICILLIN AMIDASE;

EID: 84861184711     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.04.012     Document Type: Article

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