Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent

Journal of Urology

Volumn 171, Issue 1, 2004, Pages 457-461

  Power, Richard E ^a   Doyle, Belinda T ^a   Higgins, Debra ^a   Brady, Hugh R ^a   Fitzpatrick, John M ^a   Watson, R William G ^a  

^a MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Apoptosis; Caspases; Heat shock proteins 70; Ureter; Ureteral obstruction

Indexed keywords

CASPASE 3; DNA; HEAT SHOCK PROTEIN 70; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL VIABILITY; ENZYME ACTIVITY; EPITHELIUM CELL; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRETCHING; URETER OBSTRUCTION;

EID: 0348109387     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000091106.61065.e3     Document Type: Article

References (18)

1. Sheehan, S. J., Moran, K. T., Dowsett, D. J. and Fitzpatrick, J. M.: Renal haemodynamics and prostaglandin synthesis in partial unilateral ureteric obstruction. Urol Res, 22: 279, 1994
2. Truong, L. D., Petrusevska, G., Yang, G., Gurpinar, T., Shappell, S., Lechago, J. et al: Cell apoptosis and proliferation in experimental chronic obstructive uropathy. Kidney Int, 50: 200, 1996
3. Gaudio, K. M., Siegel, N. J., Hayslett, J. P. and Kashgarian, M.: Renal perfusion and intratubular pressure during ureteral occlusion in the rat. Am J Physiol, 238: F205, 1980
4. Vaughan, E. D., Jr., Shenasky, J. H., 2nd and Gillenwater, J. Y.: Mechanism of acute hemodynamic response to ureteral occlusion. Invest Urol, 9: 109, 1971
5. Gobe, G. C. and Axelsen, R. A.: Genesis of renal tubular atrophy in experimental hydronephrosis in the rat. Role of apoptosis. Lab Invest, 56: 273, 1987
6. Ishidoya, S., Morrissey, J., McCracken, R., Reyes, A. and Klahr, S.: Angiotensin II receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction. Kidney Int, 47: 1285, 1995
7. Miyajima, A., Chen, J., Lawrence, C., Ledbetter, S., Soslow, R. A., Stern, J. et al: Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction. Kidney Int, 58: 2301, 2000
8. Miyajima, A., Chen, J., Poppas, D. P., Vaughan, E. D., Jr. and Felsen, D.: Role of nitric oxide in renal tubular apoptosis of unilateral ureteral obstruction. Kidney Int, 59: 1290, 2001
9. Sumpio, B. E. and Banes, A. J.: Response of porcine aortic smooth muscle to cyclic tensional deformation in culture. J Surg Res, 44: 696, 1988
10. Chevalier, R. L., Smith, C. D., Wolstenholme, J., Krajewski, S. and Reed, J. C.: Chronic ureteral obstruction in the rat suppresses renal tubular Bcl-2 and stimulates apoptosis. Exp Nephrol, 8: 115, 2000
11. Hegarty, N. J., Young, L. S., Kirwan, C. N., O'Neill, A. J., Bouchier-Hayes, D. M., Sweeney, P. et al: Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow. Kidney Int, 59: 1059, 2001
12. Leri, A., Claudio, P. P., Li, Q., Wang, X., Reiss, K., Wang, S. et al: Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest, 101: 1326, 1998
13. Hakeda, Y., Arakawa, T., Ogasawara, A. and Kumegawa, M.: Recent progress in studies on osteocytes-osteocytes and mechanical stress. Kaibogaku Zasshi, 75: 451, 2000
14. Truong, L. D., Choi, Y. J., Tsao, C. C., Ayala, G., Sheikh-Hamad, D., Nassar, G. et al: Renal cell apoptosis in chronic obstructive uropathy: the roles of caspases. Kidney Int, 60: 924, 2001
15. Beere, H. M., Wolf, B. B., Cain, K., Mosser, D. D., Mahboubi, A., Kuwana, T. et al: Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol, 2: 469, 2000
16. Lin, K. C., Krieg, R. J., Jr., Saborio, P. and Chan, J. C.: Increased heat shock protein-70 in unilateral ureteral obstruction in rats. Mol Genet Metab, 65: 303, 1998
17. Kim, D., Somji, S., Garrett, S. H., Sens, M. A., Shukla, D. and Sens, D. A.: Expression of hsp 27, hsp 60, hsc 70, and hsp 70 by immortalized human proximal tubule cells (HK-2) following exposure to heat shock, sodium arsenite, or cadmium chloride. J Toxicol Environ Health A, 63: 475, 2001
18. Vaudry, D., Pamantung, T. F., Basille, M., Rousselle, C., Fournier, A., Vaudry, H. et al: PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis. Eur J Neurosci, 15: 1451, 2002