-
1
-
-
0016812082
-
The functional significance of vitamin K action. Difference in phospholipid binding between normal and abnormal prothrombin
-
Esmon CT, Suttie JW, Jackson CM. The functional significance of vitamin K action. Difference in phospholipid binding between normal and abnormal prothrombin. J Biol Chem 1975, 250:4095-4099.
-
(1975)
J Biol Chem
, vol.250
, pp. 4095-4099
-
-
Esmon, C.T.1
Suttie, J.W.2
Jackson, C.M.3
-
2
-
-
0018622772
-
The contribution of bovine Factor V and Factor Va to the activity of prothrombinase
-
Nesheim ME, Taswell JB, Mann KG. The contribution of bovine Factor V and Factor Va to the activity of prothrombinase. J Biol Chem 1979, 254:10952-10962.
-
(1979)
J Biol Chem
, vol.254
, pp. 10952-10962
-
-
Nesheim, M.E.1
Taswell, J.B.2
Mann, K.G.3
-
3
-
-
0018907213
-
The role of phospholipids and factor Va in the prothrombinase complex
-
Rosing J, Tans G, Govers-Riemslag JW, Zwaal RF, Hemker HC. The role of phospholipids and factor Va in the prothrombinase complex. J Biol Chem 1980, 255:274-283.
-
(1980)
J Biol Chem
, vol.255
, pp. 274-283
-
-
Rosing, J.1
Tans, G.2
Govers-Riemslag, J.W.3
Zwaal, R.F.4
Hemker, H.C.5
-
4
-
-
0018786088
-
The subunit structure of thrombin-activated factor V. Isolation of activated factor V, separation of subunits, and reconstitution of biological activity
-
Esmon CT. The subunit structure of thrombin-activated factor V. Isolation of activated factor V, separation of subunits, and reconstitution of biological activity. J Biol Chem 1979, 254:964-973.
-
(1979)
J Biol Chem
, vol.254
, pp. 964-973
-
-
Esmon, C.T.1
-
5
-
-
0018378387
-
Isolation and characterization of single chain bovine factor V
-
Nesheim ME, Myrmel KH, Hibbard L, Mann KG. Isolation and characterization of single chain bovine factor V. J Biol Chem 1979, 254:508-517.
-
(1979)
J Biol Chem
, vol.254
, pp. 508-517
-
-
Nesheim, M.E.1
Myrmel, K.H.2
Hibbard, L.3
Mann, K.G.4
-
6
-
-
75949141239
-
Chemistry and Physiology of the Fibrinogen-Fibrin Transition
-
Laki K, Gladner JA. Chemistry and Physiology of the Fibrinogen-Fibrin Transition. Physiol Rev 1964, 44:127-160.
-
(1964)
Physiol Rev
, vol.44
, pp. 127-160
-
-
Laki, K.1
Gladner, J.A.2
-
7
-
-
0015826853
-
Structural aspects of the fibrinogen to fibrin conversion
-
Doolittle RF. Structural aspects of the fibrinogen to fibrin conversion. Adv Protein Chem 1973, 27:1-109.
-
(1973)
Adv Protein Chem
, vol.27
, pp. 1-109
-
-
Doolittle, R.F.1
-
8
-
-
0014422750
-
The transpeptidase system which crosslinks fibrin by gamma-glutamyle-episilon-lysine bonds
-
10.1016/0006-291X(68)90734-1, 5656070
-
Lorand L, Downey J, Gotoh T, Jacobsen A, Tokura S. The transpeptidase system which crosslinks fibrin by gamma-glutamyle-episilon-lysine bonds. Biochem Biophys Res Commun 1968, 31:222-230. 10.1016/0006-291X(68)90734-1, 5656070.
-
(1968)
Biochem Biophys Res Commun
, vol.31
, pp. 222-230
-
-
Lorand, L.1
Downey, J.2
Gotoh, T.3
Jacobsen, A.4
Tokura, S.5
-
9
-
-
0015208063
-
Hybrid fibrin: proof of the intermolecular nature of - crosslinking units
-
10.1016/S0006-291X(71)80163-8, 5165618
-
Doolittle RF, Chen R, Lau F. Hybrid fibrin: proof of the intermolecular nature of - crosslinking units. Biochem Biophys Res Commun 1971, 44:94-100. 10.1016/S0006-291X(71)80163-8, 5165618.
-
(1971)
Biochem Biophys Res Commun
, vol.44
, pp. 94-100
-
-
Doolittle, R.F.1
Chen, R.2
Lau, F.3
-
10
-
-
33746874881
-
Determinants of specificity of factor xa interaction with its physiological inhibitors
-
10.2174/138955706777935017, 16918492
-
Rezaie AR. Determinants of specificity of factor xa interaction with its physiological inhibitors. Mini Rev Med Chem 2006, 6:859-865. 10.2174/138955706777935017, 16918492.
-
(2006)
Mini Rev Med Chem
, vol.6
, pp. 859-865
-
-
Rezaie, A.R.1
-
11
-
-
0020034464
-
Inhibition of human factor Xa by various plasma protease inhibitors
-
Ellis V, Scully M, MacGregor I, Kakkar V. Inhibition of human factor Xa by various plasma protease inhibitors. Biochim Biophys Acta 1982, 701:24-31.
-
(1982)
Biochim Biophys Acta
, vol.701
, pp. 24-31
-
-
Ellis, V.1
Scully, M.2
MacGregor, I.3
Kakkar, V.4
-
12
-
-
0017567792
-
Anticoagulant properties of bovine plasma protein C following activation by thrombin
-
10.1021/bi00645a029, 588557
-
Kisiel W, Canfield WM, Ericsson LH, Davie EW. Anticoagulant properties of bovine plasma protein C following activation by thrombin. Biochemistry 1977, 16:5824-5831. 10.1021/bi00645a029, 588557.
-
(1977)
Biochemistry
, vol.16
, pp. 5824-5831
-
-
Kisiel, W.1
Canfield, W.M.2
Ericsson, L.H.3
Davie, E.W.4
-
13
-
-
0025888388
-
Activated protein C-catalyzed inactivation of human factor VIII and factor VIIIa. Identification of cleavage sites and correlation of proteolysis with cofactor activity
-
Fay PJ, Smudzin TM, Walker FJ. Activated protein C-catalyzed inactivation of human factor VIII and factor VIIIa. Identification of cleavage sites and correlation of proteolysis with cofactor activity. J Biol Chem 1991, 266:20139-20145.
-
(1991)
J Biol Chem
, vol.266
, pp. 20139-20145
-
-
Fay, P.J.1
Smudzin, T.M.2
Walker, F.J.3
-
14
-
-
0019849380
-
Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation
-
Walker FJ. Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation. J Biol Chem 1981, 256:11128-11131.
-
(1981)
J Biol Chem
, vol.256
, pp. 11128-11131
-
-
Walker, F.J.1
-
15
-
-
0028110027
-
The mechanism of inactivation of human factor V and human factor Va by activated protein C
-
Kalafatis M, Rand MD, Mann KG. The mechanism of inactivation of human factor V and human factor Va by activated protein C. J Biol Chem 1994, 269:31869-31880.
-
(1994)
J Biol Chem
, vol.269
, pp. 31869-31880
-
-
Kalafatis, M.1
Rand, M.D.2
Mann, K.G.3
-
16
-
-
0141819138
-
The protein C pathway
-
10.1378/chest.124.3_suppl.26S, 12970121
-
Esmon CT. The protein C pathway. Chest 2003, 124:26S-32S. 10.1378/chest.124.3_suppl.26S, 12970121.
-
(2003)
Chest
, vol.124
-
-
Esmon, C.T.1
-
17
-
-
55249124089
-
Regulation of coagulation by protein S
-
10.1097/MOH.0b013e328309ec97, 18695379
-
Castoldi E, Hackeng TM. Regulation of coagulation by protein S. Curr Opin Hematol 2008, 15:529-536. 10.1097/MOH.0b013e328309ec97, 18695379.
-
(2008)
Curr Opin Hematol
, vol.15
, pp. 529-536
-
-
Castoldi, E.1
Hackeng, T.M.2
-
18
-
-
79961061714
-
Protein C inhibitor
-
10.1055/s-0031-1276583, 21805440
-
Meijers JC, Herwald H. Protein C inhibitor. Semin Thromb Hemost 2011, 37:349-354. 10.1055/s-0031-1276583, 21805440.
-
(2011)
Semin Thromb Hemost
, vol.37
, pp. 349-354
-
-
Meijers, J.C.1
Herwald, H.2
-
19
-
-
0028845757
-
Protein C inhibitor is a potent inhibitor of the thrombin-thrombomodulin complex
-
10.1074/jbc.270.43.25336, 7592694
-
Rezaie AR, Cooper ST, Church FC, Esmon CT. Protein C inhibitor is a potent inhibitor of the thrombin-thrombomodulin complex. J Biol Chem 1995, 270:25336-25339. 10.1074/jbc.270.43.25336, 7592694.
-
(1995)
J Biol Chem
, vol.270
, pp. 25336-25339
-
-
Rezaie, A.R.1
Cooper, S.T.2
Church, F.C.3
Esmon, C.T.4
-
20
-
-
68349126914
-
Basic mechanisms and pathogenesis of venous thrombosis
-
10.1016/j.blre.2009.07.002, 2762278, 19683659
-
Esmon CT. Basic mechanisms and pathogenesis of venous thrombosis. Blood Rev 2009, 23:225-229. 10.1016/j.blre.2009.07.002, 2762278, 19683659.
-
(2009)
Blood Rev
, vol.23
, pp. 225-229
-
-
Esmon, C.T.1
-
21
-
-
0027446268
-
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C
-
10.1073/pnas.90.3.1004, 45799, 8430067
-
Dahlback B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci U S A 1993, 90:1004-1008. 10.1073/pnas.90.3.1004, 45799, 8430067.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1004-1008
-
-
Dahlback, B.1
Carlsson, M.2
Svensson, P.J.3
-
22
-
-
0028314865
-
Mutation in blood coagulation factor V associated with resistance to activated protein C
-
10.1038/369064a0, 8164741
-
Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994, 369:64-67. 10.1038/369064a0, 8164741.
-
(1994)
Nature
, vol.369
, pp. 64-67
-
-
Bertina, R.M.1
Koeleman, B.P.2
Koster, T.3
Rosendaal, F.R.4
Dirven, R.J.5
de Ronde, H.6
van der Velden, P.A.7
Reitsma, P.H.8
-
23
-
-
0023001147
-
The binding of activated protein C to factors V and Va
-
Krishnaswamy S, Williams EB, Mann KG. The binding of activated protein C to factors V and Va. J Biol Chem 1986, 261:9684-9693.
-
(1986)
J Biol Chem
, vol.261
, pp. 9684-9693
-
-
Krishnaswamy, S.1
Williams, E.B.2
Mann, K.G.3
-
24
-
-
0027954554
-
Construction, expression, and properties of a recombinant chimeric human protein C with replacement of its growth factor-like domains by those of human coagulation factor IX
-
10.1021/bi00169a025, 8292611
-
Yu S, Zhang L, Jhingan A, Christiansen WT, Castellino FJ. Construction, expression, and properties of a recombinant chimeric human protein C with replacement of its growth factor-like domains by those of human coagulation factor IX. Biochemistry 1994, 33:823-831. 10.1021/bi00169a025, 8292611.
-
(1994)
Biochemistry
, vol.33
, pp. 823-831
-
-
Yu, S.1
Zhang, L.2
Jhingan, A.3
Christiansen, W.T.4
Castellino, F.J.5
-
25
-
-
33751385288
-
A novel exosite in the light chain of human activated protein C essential for interaction with blood coagulation factor Va
-
10.1021/bi00210a014, 8251484
-
Mesters RM, Heeb MJ, Griffin JH. A novel exosite in the light chain of human activated protein C essential for interaction with blood coagulation factor Va. Biochemistry 1993, 32:12656-12663. 10.1021/bi00210a014, 8251484.
-
(1993)
Biochemistry
, vol.32
, pp. 12656-12663
-
-
Mesters, R.M.1
Heeb, M.J.2
Griffin, J.H.3
-
26
-
-
53049089511
-
Identification of surface epitopes of human coagulation factor Va that are important for interaction with activated protein C and heparin
-
10.1074/jbc.M801724200, 18519572
-
Segers K, Dahlback B, Rosing J, Nicolaes GA. Identification of surface epitopes of human coagulation factor Va that are important for interaction with activated protein C and heparin. J Biol Chem 2008, 283:22573-22581. 10.1074/jbc.M801724200, 18519572.
-
(2008)
J Biol Chem
, vol.283
, pp. 22573-22581
-
-
Segers, K.1
Dahlback, B.2
Rosing, J.3
Nicolaes, G.A.4
-
27
-
-
35348941127
-
Factor Va residues 311-325 represent an activated protein C binding region
-
10.1074/jbc.M704316200, 17646160
-
Yegneswaran S, Kojima Y, Nguyen PM, Gale AJ, Heeb MJ, Griffin JH. Factor Va residues 311-325 represent an activated protein C binding region. J Biol Chem 2007, 282:28353-28361. 10.1074/jbc.M704316200, 17646160.
-
(2007)
J Biol Chem
, vol.282
, pp. 28353-28361
-
-
Yegneswaran, S.1
Kojima, Y.2
Nguyen, P.M.3
Gale, A.J.4
Heeb, M.J.5
Griffin, J.H.6
-
28
-
-
77954943563
-
Inhibition of thrombin formation by active site mutated (S360A) activated protein C
-
10.1074/jbc.M110.131029, 2906281, 20484050
-
Nicolaes GA, Bock PE, Segers K, Wildhagen KC, Dahlback B, Rosing J. Inhibition of thrombin formation by active site mutated (S360A) activated protein C. J Biol Chem 2010, 285:22890-22900. 10.1074/jbc.M110.131029, 2906281, 20484050.
-
(2010)
J Biol Chem
, vol.285
, pp. 22890-22900
-
-
Nicolaes, G.A.1
Bock, P.E.2
Segers, K.3
Wildhagen, K.C.4
Dahlback, B.5
Rosing, J.6
-
29
-
-
0028939318
-
Characterization of the molecular defect in factor VR506Q
-
10.1074/jbc.270.8.4053, 7876154
-
Kalafatis M, Bertina RM, Rand MD, Mann KG. Characterization of the molecular defect in factor VR506Q. J Biol Chem 1995, 270:4053-4057. 10.1074/jbc.270.8.4053, 7876154.
-
(1995)
J Biol Chem
, vol.270
, pp. 4053-4057
-
-
Kalafatis, M.1
Bertina, R.M.2
Rand, M.D.3
Mann, K.G.4
-
30
-
-
0027744465
-
Role of the membrane in the inactivation of factor Va by activated protein C
-
Kalafatis M, Mann KG. Role of the membrane in the inactivation of factor Va by activated protein C. J Biol Chem 1993, 268:27246-27257.
-
(1993)
J Biol Chem
, vol.268
, pp. 27246-27257
-
-
Kalafatis, M.1
Mann, K.G.2
-
31
-
-
0029133654
-
Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C
-
10.1074/jbc.270.36.21158, 7673148
-
Nicolaes GA, Tans G, Thomassen MC, Hemker HC, Pabinger I, Varadi K, Schwarz HP, Rosing J. Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C. J Biol Chem 1995, 270:21158-21166. 10.1074/jbc.270.36.21158, 7673148.
-
(1995)
J Biol Chem
, vol.270
, pp. 21158-21166
-
-
Nicolaes, G.A.1
Tans, G.2
Thomassen, M.C.3
Hemker, H.C.4
Pabinger, I.5
Varadi, K.6
Schwarz, H.P.7
Rosing, J.8
-
32
-
-
0030843304
-
Activated protein C cleavage of factor Va leads to dissociation of the A2 domain
-
10.1074/jbc.272.33.20678, 9252387
-
Mann KG, Hockin MF, Begin KJ, Kalafatis M. Activated protein C cleavage of factor Va leads to dissociation of the A2 domain. J Biol Chem 1997, 272:20678-20683. 10.1074/jbc.272.33.20678, 9252387.
-
(1997)
J Biol Chem
, vol.272
, pp. 20678-20683
-
-
Mann, K.G.1
Hockin, M.F.2
Begin, K.J.3
Kalafatis, M.4
-
33
-
-
0033602920
-
A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition
-
10.1021/bi981966e, 10346914
-
Hockin MF, Cawthern KM, Kalafatis M, Mann KG. A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition. Biochemistry 1999, 38:6918-6934. 10.1021/bi981966e, 10346914.
-
(1999)
Biochemistry
, vol.38
, pp. 6918-6934
-
-
Hockin, M.F.1
Cawthern, K.M.2
Kalafatis, M.3
Mann, K.G.4
-
34
-
-
77954349942
-
Down regulation of prothrombinase by activated protein C during prothrombin activation
-
10.1160/TH09-09-0650, 3152479, 20390226
-
Kim PY, Nesheim ME. Down regulation of prothrombinase by activated protein C during prothrombin activation. Thromb Haemost 2010, 104:61-70. 10.1160/TH09-09-0650, 3152479, 20390226.
-
(2010)
Thromb Haemost
, vol.104
, pp. 61-70
-
-
Kim, P.Y.1
Nesheim, M.E.2
-
35
-
-
0020079791
-
Studies of the capacity of factor Xa to protect factor Va from inactivation by activated protein C
-
Nesheim ME, Canfield WM, Kisiel W, Mann KG. Studies of the capacity of factor Xa to protect factor Va from inactivation by activated protein C. J Biol Chem 1982, 257:1443-1447.
-
(1982)
J Biol Chem
, vol.257
, pp. 1443-1447
-
-
Nesheim, M.E.1
Canfield, W.M.2
Kisiel, W.3
Mann, K.G.4
-
36
-
-
33845974902
-
Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va
-
10.1074/jbc.M606441200, 16935856
-
Norstrom EA, Tran S, Steen M, Dahlback B. Effects of factor Xa and protein S on the individual activated protein C-mediated cleavages of coagulation factor Va. J Biol Chem 2006, 281:31486-31494. 10.1074/jbc.M606441200, 16935856.
-
(2006)
J Biol Chem
, vol.281
, pp. 31486-31494
-
-
Norstrom, E.A.1
Tran, S.2
Steen, M.3
Dahlback, B.4
-
37
-
-
0028810678
-
Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C
-
10.1074/jbc.270.46.27852, 7499257
-
Rosing J, Hoekema L, Nicolaes GA, Thomassen MC, Hemker HC, Varadi K, Schwarz HP, Tans G. Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C. J Biol Chem 1995, 270:27852-27858. 10.1074/jbc.270.46.27852, 7499257.
-
(1995)
J Biol Chem
, vol.270
, pp. 27852-27858
-
-
Rosing, J.1
Hoekema, L.2
Nicolaes, G.A.3
Thomassen, M.C.4
Hemker, H.C.5
Varadi, K.6
Schwarz, H.P.7
Tans, G.8
-
38
-
-
0020628416
-
Inactivation of human coagulation factor V by activated protein C
-
Suzuki K, Stenflo J, Dahlback B, Teodorsson B. Inactivation of human coagulation factor V by activated protein C. J Biol Chem 1983, 258:1914-1920.
-
(1983)
J Biol Chem
, vol.258
, pp. 1914-1920
-
-
Suzuki, K.1
Stenflo, J.2
Dahlback, B.3
Teodorsson, B.4
-
39
-
-
43749109436
-
Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va
-
10.1074/jbc.M708036200, 18198180
-
Tran S, Norstrom E, Dahlback B. Effects of prothrombin on the individual activated protein C-mediated cleavages of coagulation factor Va. J Biol Chem 2008, 283:6648-6655. 10.1074/jbc.M708036200, 18198180.
-
(2008)
J Biol Chem
, vol.283
, pp. 6648-6655
-
-
Tran, S.1
Norstrom, E.2
Dahlback, B.3
-
40
-
-
60849128832
-
Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C
-
2730196, 19132189
-
Yegneswaran S, Nguyen PM, Gale AJ, Griffin JH. Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C. Thromb Haemost 2009, 101:55-61. 2730196, 19132189.
-
(2009)
Thromb Haemost
, vol.101
, pp. 55-61
-
-
Yegneswaran, S.1
Nguyen, P.M.2
Gale, A.J.3
Griffin, J.H.4
-
41
-
-
0030608856
-
The effect of Arg306- Ala and Arg506- Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S
-
10.1002/pro.5560060922, 2143790, 9300501
-
Egan JO, Kalafatis M, Mann KG. The effect of Arg306- Ala and Arg506- Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S. Protein Sci 1997, 6:2016-2027. 10.1002/pro.5560060922, 2143790, 9300501.
-
(1997)
Protein Sci
, vol.6
, pp. 2016-2027
-
-
Egan, J.O.1
Kalafatis, M.2
Mann, K.G.3
-
42
-
-
3042720703
-
Altered inactivation pathway of factor Va by activated protein C in the presence of heparin
-
10.1111/j.1432-1033.2004.04201.x, 15206937
-
Nicolaes GA, Sorensen KW, Friedrich U, Tans G, Rosing J, Autin L, Dahlback B, Villoutreix BO. Altered inactivation pathway of factor Va by activated protein C in the presence of heparin. Eur J Biochem 2004, 271:2724-2736. 10.1111/j.1432-1033.2004.04201.x, 15206937.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2724-2736
-
-
Nicolaes, G.A.1
Sorensen, K.W.2
Friedrich, U.3
Tans, G.4
Rosing, J.5
Autin, L.6
Dahlback, B.7
Villoutreix, B.O.8
-
43
-
-
77749330743
-
The impact of uncertainty in a blood coagulation model
-
10.1093/imammb/dqp011, 19451209
-
Danforth CM, Orfeo T, Mann KG, Brummel-Ziedins KE, Everse SJ. The impact of uncertainty in a blood coagulation model. Math Med Biol 2009, 26:323-336. 10.1093/imammb/dqp011, 19451209.
-
(2009)
Math Med Biol
, vol.26
, pp. 323-336
-
-
Danforth, C.M.1
Orfeo, T.2
Mann, K.G.3
Brummel-Ziedins, K.E.4
Everse, S.J.5
-
44
-
-
0018715761
-
The inhibition of blood coagulation by activated Protein C through the selective inactivation of activated Factor V
-
10.1016/0005-2744(79)90103-7, 508770
-
Walker FJ, Sexton PW, Esmon CT. The inhibition of blood coagulation by activated Protein C through the selective inactivation of activated Factor V. Biochim Biophys Acta 1979, 571:333-342. 10.1016/0005-2744(79)90103-7, 508770.
-
(1979)
Biochim Biophys Acta
, vol.571
, pp. 333-342
-
-
Walker, F.J.1
Sexton, P.W.2
Esmon, C.T.3
-
45
-
-
0019835197
-
Assembly of the prothrombinase complex in the absence of prothrombin
-
Nesheim ME, Eid S, Mann KG. Assembly of the prothrombinase complex in the absence of prothrombin. J Biol Chem 1981, 256:9874-9882.
-
(1981)
J Biol Chem
, vol.256
, pp. 9874-9882
-
-
Nesheim, M.E.1
Eid, S.2
Mann, K.G.3
-
46
-
-
0027936105
-
A model for the tissue factor pathway to thrombin. II. A mathematical simulation
-
Jones KC, Mann KG. A model for the tissue factor pathway to thrombin. II. A mathematical simulation. J Biol Chem 1994, 269:23367-23373.
-
(1994)
J Biol Chem
, vol.269
, pp. 23367-23373
-
-
Jones, K.C.1
Mann, K.G.2
-
47
-
-
0037166290
-
A model for the stoichiometric regulation of blood coagulation
-
10.1074/jbc.M201173200, 11893748
-
Hockin MF, Jones KC, Everse SJ, Mann KG. A model for the stoichiometric regulation of blood coagulation. J Biol Chem 2002, 277:18322-18333. 10.1074/jbc.M201173200, 11893748.
-
(2002)
J Biol Chem
, vol.277
, pp. 18322-18333
-
-
Hockin, M.F.1
Jones, K.C.2
Everse, S.J.3
Mann, K.G.4
-
48
-
-
0023858573
-
Prothrombinase complex assembly. Kinetic mechanism of enzyme assembly on phospholipid vesicles
-
Krishnaswamy S, Jones KC, Mann KG. Prothrombinase complex assembly. Kinetic mechanism of enzyme assembly on phospholipid vesicles. J Biol Chem 1988, 263:3823-3834.
-
(1988)
J Biol Chem
, vol.263
, pp. 3823-3834
-
-
Krishnaswamy, S.1
Jones, K.C.2
Mann, K.G.3
-
49
-
-
78650651123
-
Cellular regulation of blood coagulation: a model for venous stasis
-
10.1182/blood-2010-01-266395, 3031393, 20864579
-
Campbell JE, Brummel-Ziedins KE, Butenas S, Mann KG. Cellular regulation of blood coagulation: a model for venous stasis. Blood 2010, 116:6082-6091. 10.1182/blood-2010-01-266395, 3031393, 20864579.
-
(2010)
Blood
, vol.116
, pp. 6082-6091
-
-
Campbell, J.E.1
Brummel-Ziedins, K.E.2
Butenas, S.3
Mann, K.G.4
-
50
-
-
0023655669
-
Proteolysis of factor Va by factor Xa and activated protein C
-
Odegaard B, Mann K. Proteolysis of factor Va by factor Xa and activated protein C. J Biol Chem 1987, 262:11233-11238.
-
(1987)
J Biol Chem
, vol.262
, pp. 11233-11238
-
-
Odegaard, B.1
Mann, K.2
-
51
-
-
79955950241
-
Cleavage at both Arg306 and Arg506 is required and sufficient for timely and efficient inactivation of factor Va by activated protein C
-
10.1097/MBC.0b013e3283456c4e, 3089681, 21467919
-
Barhoover MA, Kalafatis M. Cleavage at both Arg306 and Arg506 is required and sufficient for timely and efficient inactivation of factor Va by activated protein C. Blood Coagul Fibrinolysis 2011, 22:317-324. 10.1097/MBC.0b013e3283456c4e, 3089681, 21467919.
-
(2011)
Blood Coagul Fibrinolysis
, vol.22
, pp. 317-324
-
-
Barhoover, M.A.1
Kalafatis, M.2
-
52
-
-
84865304308
-
A molecular model of the human prothrombinase complex
-
Springer, Tokyo, Tanaka K, Davie EW
-
Everse SJ, Adams TE, Mann KG. A molecular model of the human prothrombinase complex. Recent Advances in Thrombosis and Hemostasis. Volume 21 2008, 107-132. Springer, Tokyo, Tanaka K, Davie EW.
-
(2008)
Recent Advances in Thrombosis and Hemostasis. Volume 21
, pp. 107-132
-
-
Everse, S.J.1
Adams, T.E.2
Mann, K.G.3
-
53
-
-
33646060435
-
Proposed structural models of the prothrombinase (FXa-FVa) complex
-
10.1002/prot.20848, 16437549
-
Autin L, Steen M, Dahlback B, Villoutreix BO. Proposed structural models of the prothrombinase (FXa-FVa) complex. Proteins 2006, 63:440-450. 10.1002/prot.20848, 16437549.
-
(2006)
Proteins
, vol.63
, pp. 440-450
-
-
Autin, L.1
Steen, M.2
Dahlback, B.3
Villoutreix, B.O.4
-
54
-
-
37549070323
-
Proposed structural models of human factor Va and prothrombinase
-
Lee CJ, Lin P, Chandrasekaran V, Duke RE, Everse SJ, Perera L, Pedersen LG. Proposed structural models of human factor Va and prothrombinase. J Thromb Haemost 2008, 6:83-89.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 83-89
-
-
Lee, C.J.1
Lin, P.2
Chandrasekaran, V.3
Duke, R.E.4
Everse, S.J.5
Perera, L.6
Pedersen, L.G.7
-
55
-
-
0032499683
-
Structural basis for chemical inhibition of human blood coagulation factor Xa
-
10.1073/pnas.95.12.6630, 22577, 9618463
-
Kamata K, Kawamoto H, Honma T, Iwama T, Kim SH. Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc Natl Acad Sci U S A 1998, 95:6630-6635. 10.1073/pnas.95.12.6630, 22577, 9618463.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6630-6635
-
-
Kamata, K.1
Kawamoto, H.2
Honma, T.3
Iwama, T.4
Kim, S.H.5
-
56
-
-
2942669901
-
The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function
-
10.1073/pnas.0403072101, 428447, 15184653
-
Adams TE, Hockin MF, Mann KG, Everse SJ. The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function. Proc Natl Acad Sci U S A 2004, 101:8918-8923. 10.1073/pnas.0403072101, 428447, 15184653.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8918-8923
-
-
Adams, T.E.1
Hockin, M.F.2
Mann, K.G.3
Everse, S.J.4
-
57
-
-
3042958993
-
The X-ray structure of human serum ceruloplasmin at 3.1 angstrom: Nature of the copper centres
-
Zaitseva I, Zaitsev V, Card G, Moshkov K, Bax B, Ralph A, Lindley P. The X-ray structure of human serum ceruloplasmin at 3.1 angstrom: Nature of the copper centres. J Biol Inorg Chem 1996, 1:15-23.
-
(1996)
J Biol Inorg Chem
, vol.1
, pp. 15-23
-
-
Zaitseva, I.1
Zaitsev, V.2
Card, G.3
Moshkov, K.4
Bax, B.5
Ralph, A.6
Lindley, P.7
-
58
-
-
0021718109
-
Loss of prothrombin and of factor Xa-factor Va interactions upon inactivation of factor Va by activated protein C
-
Guinto ER, Esmon CT. Loss of prothrombin and of factor Xa-factor Va interactions upon inactivation of factor Va by activated protein C. J Biol Chem 1984, 259:13986-13992.
-
(1984)
J Biol Chem
, vol.259
, pp. 13986-13992
-
-
Guinto, E.R.1
Esmon, C.T.2
-
59
-
-
34250365394
-
The local phospholipid environment modulates the activation of blood clotting
-
Shaw AW, Pureza VS, Sligar SG, Morrissey JH. The local phospholipid environment modulates the activation of blood clotting. J Biol Chem 2007, 282:6556-6563.
-
(2007)
J Biol Chem
, vol.282
, pp. 6556-6563
-
-
Shaw, A.W.1
Pureza, V.S.2
Sligar, S.G.3
Morrissey, J.H.4
-
60
-
-
0020633335
-
The interaction of bovine factor V and factor V-derived peptides with phospholipid vesicles
-
Higgins DL, Mann KG. The interaction of bovine factor V and factor V-derived peptides with phospholipid vesicles. J Biol Chem 1983, 258:6503-6508.
-
(1983)
J Biol Chem
, vol.258
, pp. 6503-6508
-
-
Higgins, D.L.1
Mann, K.G.2
-
61
-
-
0018780186
-
Phospholipid-binding properties of bovine factor V and factor Va
-
10.1021/bi00587a023, 486430
-
Bloom JW, Nesheim ME, Mann KG. Phospholipid-binding properties of bovine factor V and factor Va. Biochemistry 1979, 18:4419-4425. 10.1021/bi00587a023, 486430.
-
(1979)
Biochemistry
, vol.18
, pp. 4419-4425
-
-
Bloom, J.W.1
Nesheim, M.E.2
Mann, K.G.3
-
62
-
-
0030036599
-
Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: implications for protein-membrane contact
-
10.1021/bi960280o, 8679573
-
Lu Y, Nelsestuen GL. Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: implications for protein-membrane contact. Biochemistry 1996, 35:8193-8200. 10.1021/bi960280o, 8679573.
-
(1996)
Biochemistry
, vol.35
, pp. 8193-8200
-
-
Lu, Y.1
Nelsestuen, G.L.2
-
63
-
-
0023949710
-
The binding of factor Va to phospholipid vesicles
-
Krishnaswamy S, Mann KG. The binding of factor Va to phospholipid vesicles. J Biol Chem 1988, 263:5714-5723.
-
(1988)
J Biol Chem
, vol.263
, pp. 5714-5723
-
-
Krishnaswamy, S.1
Mann, K.G.2
-
64
-
-
0032502796
-
A chimeric protein C containing the prothrombin Gla domain exhibits increased anticoagulant activity and altered phospholipid specificity
-
10.1074/jbc.273.15.9031, 9535891
-
Smirnov MD, Safa O, Regan L, Mather T, Stearns-Kurosawa DJ, Kurosawa S, Rezaie AR, Esmon NL, Esmon CT. A chimeric protein C containing the prothrombin Gla domain exhibits increased anticoagulant activity and altered phospholipid specificity. J Biol Chem 1998, 273:9031-9040. 10.1074/jbc.273.15.9031, 9535891.
-
(1998)
J Biol Chem
, vol.273
, pp. 9031-9040
-
-
Smirnov, M.D.1
Safa, O.2
Regan, L.3
Mather, T.4
Stearns-Kurosawa, D.J.5
Kurosawa, S.6
Rezaie, A.R.7
Esmon, N.L.8
Esmon, C.T.9
-
65
-
-
67849103770
-
Protein-membrane interactions: blood clotting on nanoscale bilayers
-
2839880, 19630793
-
Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Rienstra CM, Kijac AZ, Ohkubo YZ, Tajkhorshid E. Protein-membrane interactions: blood clotting on nanoscale bilayers. J Thromb Haemost 2009, 7(Suppl 1):169-172. 2839880, 19630793.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.SUPPL. 1
, pp. 169-172
-
-
Morrissey, J.H.1
Pureza, V.2
Davis-Harrison, R.L.3
Sligar, S.G.4
Rienstra, C.M.5
Kijac, A.Z.6
Ohkubo, Y.Z.7
Tajkhorshid, E.8
-
66
-
-
0026722694
-
The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C
-
10.1111/j.1432-1033.1992.tb17171.x, 1387359
-
Bakker HM, Tans G, Janssen-Claessen T, Thomassen MC, Hemker HC, Griffin JH, Rosing J. The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C. Eur J Biochem 1992, 208:171-178. 10.1111/j.1432-1033.1992.tb17171.x, 1387359.
-
(1992)
Eur J Biochem
, vol.208
, pp. 171-178
-
-
Bakker, H.M.1
Tans, G.2
Janssen-Claessen, T.3
Thomassen, M.C.4
Hemker, H.C.5
Griffin, J.H.6
Rosing, J.7
-
67
-
-
0028804699
-
On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies
-
10.1172/JCI117657, 295433, 7814631
-
Smirnov MD, Triplett DT, Comp PC, Esmon NL, Esmon CT. On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies. J Clin Invest 1995, 95:309-316. 10.1172/JCI117657, 295433, 7814631.
-
(1995)
J Clin Invest
, vol.95
, pp. 309-316
-
-
Smirnov, M.D.1
Triplett, D.T.2
Comp, P.C.3
Esmon, N.L.4
Esmon, C.T.5
-
68
-
-
0001023589
-
The effect of membrane composition on the hemostatic balance
-
10.1021/bi982538b, 10090745
-
Smirnov MD, Ford DA, Esmon CT, Esmon NL. The effect of membrane composition on the hemostatic balance. Biochemistry 1999, 38:3591-3598. 10.1021/bi982538b, 10090745.
-
(1999)
Biochemistry
, vol.38
, pp. 3591-3598
-
-
Smirnov, M.D.1
Ford, D.A.2
Esmon, C.T.3
Esmon, N.L.4
-
69
-
-
80052495060
-
Simulated surface-induced thrombin generation in a flow field
-
10.1016/j.bpj.2011.05.056, 3136770, 21767479
-
Jordan SW, Chaikof EL. Simulated surface-induced thrombin generation in a flow field. Biophys J 2011, 101:276-286. 10.1016/j.bpj.2011.05.056, 3136770, 21767479.
-
(2011)
Biophys J
, vol.101
, pp. 276-286
-
-
Jordan, S.W.1
Chaikof, E.L.2
-
70
-
-
1342312137
-
A mathematical model of lipid-mediated thrombin generation
-
10.1093/imammb/20.1.105, 12974500
-
Bungay SD, Gentry PA, Gentry RD. A mathematical model of lipid-mediated thrombin generation. Math Med Biol 2003, 20:105-129. 10.1093/imammb/20.1.105, 12974500.
-
(2003)
Math Med Biol
, vol.20
, pp. 105-129
-
-
Bungay, S.D.1
Gentry, P.A.2
Gentry, R.D.3
-
71
-
-
2342643483
-
The kinetic model and simulation of blood coagulation-the kinetic influence of activated protein C
-
10.1016/j.medengphy.2004.01.003, 15121060
-
Qiao YH, Xu CQ, Zeng YJ, Xu XH, Zhao H, Xu H. The kinetic model and simulation of blood coagulation-the kinetic influence of activated protein C. Med Eng Phys 2004, 26:341-347. 10.1016/j.medengphy.2004.01.003, 15121060.
-
(2004)
Med Eng Phys
, vol.26
, pp. 341-347
-
-
Qiao, Y.H.1
Xu, C.Q.2
Zeng, Y.J.3
Xu, X.H.4
Zhao, H.5
Xu, H.6
-
72
-
-
17144393270
-
A kinetic model for simulation of blood coagulation and inhibition in the intrinsic path
-
10.1080/03091900410001709079, 15804855
-
Qiao YH, Liu JL, Zeng YJ. A kinetic model for simulation of blood coagulation and inhibition in the intrinsic path. J Med Eng Technol 2005, 29:70-74. 10.1080/03091900410001709079, 15804855.
-
(2005)
J Med Eng Technol
, vol.29
, pp. 70-74
-
-
Qiao, Y.H.1
Liu, J.L.2
Zeng, Y.J.3
-
73
-
-
47849104044
-
A model for the formation, growth, and lysis of clots in quiescent plasma. A comparison between the effects of antithrombin III deficiency and protein C deficiency
-
10.1016/j.jtbi.2008.04.015, 18539301
-
Anand M, Rajagopal K, Rajagopal KR. A model for the formation, growth, and lysis of clots in quiescent plasma. A comparison between the effects of antithrombin III deficiency and protein C deficiency. J Theor Biol 2008, 253:725-738. 10.1016/j.jtbi.2008.04.015, 18539301.
-
(2008)
J Theor Biol
, vol.253
, pp. 725-738
-
-
Anand, M.1
Rajagopal, K.2
Rajagopal, K.R.3
-
74
-
-
0035119193
-
Surface-mediated control of blood coagulation: the role of binding site densities and platelet deposition
-
10.1016/S0006-3495(01)76085-7, 1301304, 11222273
-
Kuharsky AL, Fogelson AL. Surface-mediated control of blood coagulation: the role of binding site densities and platelet deposition. Biophys J 2001, 80:1050-1074. 10.1016/S0006-3495(01)76085-7, 1301304, 11222273.
-
(2001)
Biophys J
, vol.80
, pp. 1050-1074
-
-
Kuharsky, A.L.1
Fogelson, A.L.2
-
75
-
-
31344462420
-
Coagulation under flow: the influence of flow-mediated transport on the initiation and inhibition of coagulation
-
10.1159/000089930, 16432311
-
Fogelson AL, Tania N. Coagulation under flow: the influence of flow-mediated transport on the initiation and inhibition of coagulation. Pathophysiol Haemost Thromb 2005, 34:91-108. 10.1159/000089930, 16432311.
-
(2005)
Pathophysiol Haemost Thromb
, vol.34
, pp. 91-108
-
-
Fogelson, A.L.1
Tania, N.2
-
76
-
-
31344474854
-
Blood coagulation and propagation of autowaves in flow
-
10.1159/000089933, 16432314
-
Ermakova EA, Panteleev MA, Shnol EE. Blood coagulation and propagation of autowaves in flow. Pathophysiol Haemost Thromb 2005, 34:135-142. 10.1159/000089933, 16432314.
-
(2005)
Pathophysiol Haemost Thromb
, vol.34
, pp. 135-142
-
-
Ermakova, E.A.1
Panteleev, M.A.2
Shnol, E.E.3
-
77
-
-
35348953113
-
Characterization of the threshold response of initiation of blood clotting to stimulus patch size
-
10.1529/biophysj.107.109009, 1989713, 17586576
-
Kastrup CJ, Shen F, Runyon MK, Ismagilov RF. Characterization of the threshold response of initiation of blood clotting to stimulus patch size. Biophys J 2007, 93:2969-2977. 10.1529/biophysj.107.109009, 1989713, 17586576.
-
(2007)
Biophys J
, vol.93
, pp. 2969-2977
-
-
Kastrup, C.J.1
Shen, F.2
Runyon, M.K.3
Ismagilov, R.F.4
-
78
-
-
33646149990
-
Spatial propagation and localization of blood coagulation are regulated by intrinsic and protein C pathways, respectively
-
10.1529/biophysj.105.069062, 1367302, 16326897
-
Panteleev MA, Ovanesov MV, Kireev DA, Shibeko AM, Sinauridze EI, Ananyeva NM, Butylin AA, Saenko EL, Ataullakhanov FI. Spatial propagation and localization of blood coagulation are regulated by intrinsic and protein C pathways, respectively. Biophys J 2006, 90:1489-1500. 10.1529/biophysj.105.069062, 1367302, 16326897.
-
(2006)
Biophys J
, vol.90
, pp. 1489-1500
-
-
Panteleev, M.A.1
Ovanesov, M.V.2
Kireev, D.A.3
Shibeko, A.M.4
Sinauridze, E.I.5
Ananyeva, N.M.6
Butylin, A.A.7
Saenko, E.L.8
Ataullakhanov, F.I.9
-
79
-
-
34547577428
-
Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies
-
10.1371/journal.pcbi.0030142, 1924874, 17658944
-
Luan D, Zai M, Varner JD. Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies. PLoS Comput Biol 2007, 3:e142. 10.1371/journal.pcbi.0030142, 1924874, 17658944.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Luan, D.1
Zai, M.2
Varner, J.D.3
-
80
-
-
33646776757
-
The limits of simulation of the clotting system
-
10.1111/j.1538-7836.2006.01967.x, 16706979
-
Wagenvoord R, Hemker PW, Hemker HC. The limits of simulation of the clotting system. J Thromb Haemost 2006, 4:1331-1338. 10.1111/j.1538-7836.2006.01967.x, 16706979.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1331-1338
-
-
Wagenvoord, R.1
Hemker, P.W.2
Hemker, H.C.3
-
81
-
-
0015739824
-
Simultaneous purification of bovine prothrombin and factor X. Activation of prothrombin by trypsin-activated factor X
-
Bajaj SP, Mann KG. Simultaneous purification of bovine prothrombin and factor X. Activation of prothrombin by trypsin-activated factor X. J Biol Chem 1973, 248:7729-7741.
-
(1973)
J Biol Chem
, vol.248
, pp. 7729-7741
-
-
Bajaj, S.P.1
Mann, K.G.2
-
82
-
-
0023196008
-
Activation of human prothrombin by human prothrombinase. Influence of factor Va on the reaction mechanism
-
Krishnaswamy S, Church WR, Nesheim ME, Mann KG. Activation of human prothrombin by human prothrombinase. Influence of factor Va on the reaction mechanism. J Biol Chem 1987, 262:3291-3299.
-
(1987)
J Biol Chem
, vol.262
, pp. 3291-3299
-
-
Krishnaswamy, S.1
Church, W.R.2
Nesheim, M.E.3
Mann, K.G.4
-
83
-
-
0342300993
-
Isolation of functional human coagulation factor V by using a hybridoma antibody
-
10.1073/pnas.78.1.162, 319011, 6941242
-
Katzmann JA, Nesheim ME, Hibbard LS, Mann KG. Isolation of functional human coagulation factor V by using a hybridoma antibody. Proc Natl Acad Sci U S A 1981, 78:162-166. 10.1073/pnas.78.1.162, 319011, 6941242.
-
(1981)
Proc Natl Acad Sci U S A
, vol.78
, pp. 162-166
-
-
Katzmann, J.A.1
Nesheim, M.E.2
Hibbard, L.S.3
Mann, K.G.4
-
84
-
-
0017404160
-
A simple method for the preparation of homogeneous phospholipid vesicles
-
10.1021/bi00631a035, 889789
-
Barenholz Y, Gibbes D, Litman BJ, Goll J, Thompson TE, Carlson RD. A simple method for the preparation of homogeneous phospholipid vesicles. Biochemistry 1977, 16:2806-2810. 10.1021/bi00631a035, 889789.
-
(1977)
Biochemistry
, vol.16
, pp. 2806-2810
-
-
Barenholz, Y.1
Gibbes, D.2
Litman, B.J.3
Goll, J.4
Thompson, T.E.5
Carlson, R.D.6
-
85
-
-
0025816859
-
The association of coagulation factor Xa and factor Va
-
Pryzdial EL, Mann KG. The association of coagulation factor Xa and factor Va. J Biol Chem 1991, 266:8969-8977.
-
(1991)
J Biol Chem
, vol.266
, pp. 8969-8977
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-
Pryzdial, E.L.1
Mann, K.G.2
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