The effect of Arg306 → Ala and Arg506 → Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S

Protein Science

Volumn 6, Issue 9, 1997, Pages 2016-2027

  Egan, Jack O ^a   Kalafatis, Michael ^a   Mann, Kenneth G ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Activated protein C; Factor Va inactivation; Protein S; Recombinant factor V

Indexed keywords

PROTEIN C; PROTEIN S; THROMBIN; ALANINE; ARGININE; BLOOD CLOTTING FACTOR 5A; GLUTAMINE; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD CLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; SITE DIRECTED MUTAGENESIS; ANIMAL; BINDING SITE; CHEMISTRY; CHO CELL; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; KINETICS; METABOLISM; STRUCTURE ACTIVITY RELATION;

ALANINE; ANIMALS; ARGININE; BINDING SITES; CHO CELLS; CRICETINAE; FACTOR VA; GLUTAMINE; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN C; PROTEIN S; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; TRANSFECTION;

EID: 0030608856     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560060922     Document Type: Article

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