-
1
-
-
0035824817
-
Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate
-
Alemany R, Kleuser B, Ruwisch L, Danneberg K, Lass H, Hashemi R, Spiegel S, Jakobs KH, Meyer Z.H.D. 2001. Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate. FEBS Lett 509: 239-244.
-
(2001)
FEBS Lett
, vol.509
, pp. 239-244
-
-
Alemany, R.1
Kleuser, B.2
Ruwisch, L.3
Danneberg, K.4
Lass, H.5
Hashemi, R.6
Spiegel, S.7
Jakobs, K.H.8
Meyer, Z.H.D.9
-
2
-
-
33846811196
-
Regulation and functional roles of sphingosine kinases
-
Alemany R, van Koppen CJ, Danneberg K, Ter B. M, Meyer Z.H.D. 2007. Regulation and functional roles of sphingosine kinases. Naunyn Schmiedebergs Arch Pharmacol 374: 413-428.
-
(2007)
Naunyn Schmiedebergs Arch Pharmacol
, vol.374
, pp. 413-428
-
-
Alemany, R.1
van Koppen, C.J.2
Danneberg, K.3
Ter B., M.4
Meyer, Z.H.D.5
-
3
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, et al. 2010. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465: 1084-1088.
-
(2010)
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
-
4
-
-
77953260849
-
Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons
-
Ball RW, Warren-Paquin M, Tsurudome K, Liao EH, Elazzouzi F, Cavanagh C, An B-S, Wang T-T, White JH, Haghighi AP. 2010. Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons. Neuron 66: 536-549.
-
(2010)
Neuron
, vol.66
, pp. 536-549
-
-
Ball, R.W.1
Warren-Paquin, M.2
Tsurudome, K.3
Liao, E.H.4
Elazzouzi, F.5
Cavanagh, C.6
An, B.-S.7
Wang, T.-T.8
White, J.H.9
Haghighi, A.P.10
-
5
-
-
0034960521
-
The Trio family of guaninenucleotide-exchange factors: Regulators of axon guidance
-
Bateman J, Van Vactor D. 2001. The Trio family of guaninenucleotide-exchange factors: Regulators of axon guidance. J Cell Sci 114: 1973-1980.
-
(2001)
J Cell Sci
, vol.114
, pp. 1973-1980
-
-
Bateman, J.1
van Vactor, D.2
-
6
-
-
0034532891
-
Identification and character- ization of a novel Rho-specific guanine nucleotide exchange factor
-
Blomquist A, Schworer G, Schablowski H, Psoma A, Lehnen M, Jakobs KH, Rumenapp U. 2000. Identification and character- ization of a novel Rho-specific guanine nucleotide exchange factor. Biochem J 352: 319-325.
-
(2000)
Biochem J
, vol.352
, pp. 319-325
-
-
Blomquist, A.1
Schworer, G.2
Schablowski, H.3
Psoma, A.4
Lehnen, M.5
Jakobs, K.H.6
Rumenapp, U.7
-
7
-
-
0036261720
-
Leukemia-associated Rho guanine nucleotide exchange factor promotes Gaq- coupled activation of RhoA
-
Booden MA, Siderovski DP, Der CJ. 2002. Leukemia-associated Rho guanine nucleotide exchange factor promotes Gaq- coupled activation of RhoA. Mol Cell Biol 22: 4053-4061.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4053-4061
-
-
Booden, M.A.1
Siderovski, D.P.2
Der, C.J.3
-
8
-
-
0036687577
-
Sphingosine 1-phosphate enhances spontaneous transmitter release at the frog neuromuscular junction
-
Brailoiu E, Cooper RL, Dun NJ. 2002. Sphingosine 1-phosphate enhances spontaneous transmitter release at the frog neuromuscular junction. Br J Pharmacol 136: 1093-1097.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 1093-1097
-
-
Brailoiu, E.1
Cooper, R.L.2
Dun, N.J.3
-
9
-
-
77954539153
-
Muscarinic acetylcholine receptors (mAChRs) in the nervous system: Some functions and mechanisms
-
Brown DA. 2010. Muscarinic acetylcholine receptors (mAChRs) in the nervous system: Some functions and mechanisms. J Mol Neurosci 41: 340-346.
-
(2010)
J Mol Neurosci
, vol.41
, pp. 340-346
-
-
Brown, D.A.1
-
11
-
-
78649673863
-
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate
-
doi: 10.1152/ajpcell. 00051.2010
-
Bucki R, Kulakowska A, Byfield FJ, Zendzian-Piotrowska M, Baranowski M, Marzec M, Winer JP, Ciccarelli NJ, Górski J, Drozdowski W, et al. 2010. Plasma gelsolin modulates cellular response to sphingosine 1-phosphate. Am J Physiol Cell Physiol 299: C1516-C1523. doi: 10.1152/ajpcell. 00051.2010.
-
(2010)
Am J Physiol Cell Physiol
, vol.299
-
-
Bucki, R.1
Kulakowska, A.2
Byfield, F.J.3
Zendzian-Piotrowska, M.4
Baranowski, M.5
Marzec, M.6
Winer, J.P.7
Ciccarelli, N.J.8
Górski, J.9
Drozdowski, W.10
-
12
-
-
77953805895
-
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
-
Burns AR, Wallace IM, Wildenhain J, Tyers M, Giaever G, Bader GD, Nislow C, Cutler SR, Roy PJ. 2010. A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. Nat Chem Biol 6: 549-557.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 549-557
-
-
Burns, A.R.1
Wallace, I.M.2
Wildenhain, J.3
Tyers, M.4
Giaever, G.5
Bader, G.D.6
Nislow, C.7
Cutler, S.R.8
Roy, P.J.9
-
13
-
-
65349087336
-
Synaptic vesicle docking: Sphingosine regulates syntaxin1 interaction with Munc18
-
doi: 10.1371/journal.pone.0005310
-
Camoletto PG, Vara H, Morando L, Connell E, Marletto FP, Giustetto M, Sassoè-Pognetto M, Van Veldhoven PP, Ledesma MD. 2009. Synaptic vesicle docking: Sphingosine regulates syntaxin1 interaction with Munc18. PLoS ONE 4: e5310. doi: 10.1371/journal.pone.0005310.
-
(2009)
PLoS ONE
, vol.4
-
-
Camoletto, P.G.1
Vara, H.2
Morando, L.3
Connell, E.4
Marletto, F.P.5
Giustetto, M.6
Sassoè-Pognetto, M.7
van Veldhoven, P.P.8
Ledesma, M.D.9
-
14
-
-
57149117136
-
Profiling synaptic proteins identifies regulators of insulin secretion and lifespan
-
doi: 10.1371/journal.pgen.1000283
-
Ch'ng Q, Sieburth D, Kaplan JM. 2008. Profiling synaptic proteins identifies regulators of insulin secretion and lifespan. PLoS Genet 4: e1000283. doi: 10.1371/journal.pgen.1000283.
-
(2008)
PLoS Genet
, vol.4
-
-
Ch'ng, Q.1
Sieburth, D.2
Kaplan, J.M.3
-
15
-
-
66449098305
-
Sphingosine facilitates SNARE complex assembly and activates synaptic vesicle exocytosis
-
Darios F, Wasser C, Shakirzyanova A, Giniatullin A, Goodman K, Munoz-Bravo JL, Raingo J, Jorgac ̌ evski J, Kreft M, Zorec R, et al. 2009. Sphingosine facilitates SNARE complex assembly and activates synaptic vesicle exocytosis. Neuron 62: 683-694.
-
(2009)
Neuron
, vol.62
, pp. 683-694
-
-
Darios, F.1
Wasser, C.2
Shakirzyanova, A.3
Giniatullin, A.4
Goodman, K.5
Munoz-Bravo, J.L.6
Raingo, J.7
Jorgačevski, J.8
Kreft, M.9
Zorec, R.10
-
16
-
-
53349098893
-
Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans
-
Deng X, Yin X, Allan R, Lu DD, Maurer CW, Haimovitz F.A, Fuks Z, Shaham S, Koslenick R. 2008. Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans. Science 322: 110-115.
-
(2008)
Science
, vol.322
, pp. 110-115
-
-
Deng, X.1
Yin, X.2
Allan, R.3
Lu, D.D.4
Maurer, C.W.5
Haimovitz, F.A.6
Fuks, Z.7
Shaham, S.8
Koslenick, R.9
-
17
-
-
33746627569
-
Factors regulating the abundance and localization of synaptobrevin in the plasma membrane
-
Dittman JS, Kaplan JM. 2006. Factors regulating the abundance and localization of synaptobrevin in the plasma membrane. Proc Natl Acad Sci 103: 11399-11404.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 11399-11404
-
-
Dittman, J.S.1
Kaplan, J.M.2
-
18
-
-
79955744677
-
The cholinergic system and hippocampal plasticity
-
Drever BD, Riedel G, Platt B. 2011. The cholinergic system and hippocampal plasticity. Behav Brain Res 221: 505-514.
-
(2011)
Behav Brain Res
, vol.221
, pp. 505-514
-
-
Drever, B.D.1
Riedel, G.2
Platt, B.3
-
19
-
-
33745901961
-
Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling
-
Fernandez-Alfonso T, Kwan R, Ryan TA. 2006. Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling. Neuron 51: 179-186.
-
(2006)
Neuron
, vol.51
, pp. 179-186
-
-
Fernandez-Alfonso, T.1
Kwan, R.2
Ryan, T.A.3
-
20
-
-
33646185695
-
Sensing of lysophospholipids by TRPC5 calcium channel
-
Flemming PK, Dedman AM, Xu SZ, Li J, Zeng F, Naylor J, Benham CD, Bateson AN, Muraki K, Beech DJ. 2006. Sensing of lysophospholipids by TRPC5 calcium channel. J Biol Chem 281: 4977-4982.
-
(2006)
J Biol Chem
, vol.281
, pp. 4977-4982
-
-
Flemming, P.K.1
Dedman, A.M.2
Xu, S.Z.3
Li, J.4
Zeng, F.5
Naylor, J.6
Benham, C.D.7
Bateson, A.N.8
Muraki, K.9
Beech, D.J.10
-
21
-
-
25444481075
-
A gene expression fingerprint of C. elegans embryonic motor neurons
-
doi: 10.1186/1471-2164-6-42
-
Fox RM, Von Stetina SE, Barlow SJ, Shaffer C, Olszewski KL, Moore JH, Dupuy D, Vidal M, Miller DM III. 2005. A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics 6: 42. doi: 10.1186/1471-2164-6-42.
-
(2005)
BMC Genomics
, vol.6
, pp. 42
-
-
Fox, R.M.1
von Stetina, S.E.2
Barlow, S.J.3
Shaffer, C.4
Olszewski, K.L.5
Moore, J.H.6
Dupuy, D.7
Vidal, M.8
Miller, D.M.9
-
22
-
-
0028128763
-
Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium
-
Ghosh TK, Bian J, Gill DL. 1994. Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium. J Biol Chem 269: 22628-22635.
-
(1994)
J Biol Chem
, vol.269
, pp. 22628-22635
-
-
Ghosh, T.K.1
Bian, J.2
Gill, D.L.3
-
23
-
-
33747364921
-
Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans
-
doi: 10.1371/ journal.pbio.0040261
-
Gracheva EO, Burdina AO, Holgado AM, Berthelot-Grosjean M, Ackley BD, Hadwiger G, Nonet ML, Weimer RM, Richmond JE. 2006. Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. PLoS Biol 4: 261. doi: 10.1371/ journal.pbio.0040261.
-
(2006)
PLoS Biol
, vol.4
, pp. 261
-
-
Gracheva, E.O.1
Burdina, A.O.2
Holgado, A.M.3
Berthelot-Grosjean, M.4
Ackley, B.D.5
Hadwiger, G.6
Nonet, M.L.7
Weimer, R.M.8
Richmond, J.E.9
-
24
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJF, Zhou Y, Wang X, Mazitschek R, et al. 2009. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459: 55-60.
-
(2009)
Nature
, vol.459
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
Dannenberg, J.H.4
Joseph, N.5
Gao, J.6
Nieland, T.J.F.7
Zhou, Y.8
Wang, X.9
Mazitschek, R.10
-
25
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
-
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, et al. 2009. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 325: 1254-1257.
-
(2009)
Science
, vol.325
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
Singh, S.K.6
Luo, C.7
Marmorstein, R.8
Kordula, T.9
Milstien, S.10
-
26
-
-
0025844789
-
Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans
-
Hall DH, Hedgecock EM. 1991. Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell 65: 837-847.
-
(1991)
Cell
, vol.65
, pp. 837-847
-
-
Hall, D.H.1
Hedgecock, E.M.2
-
27
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun YA, Obeid LM. 2008. Principles of bioactive lipid signalling: Lessons from sphingolipids. Nat Rev Mol Cell Biol 9: 139-150.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
28
-
-
79151479103
-
Complexin maintains vesicles in the primed state in C. elegans
-
Hobson RJ, Liu Q, Watanabe S, Jorgensen EM. 2011. Complexin maintains vesicles in the primed state in C. elegans. Curr Biol 21: 106-113.
-
(2011)
Curr Biol
, vol.21
, pp. 106-113
-
-
Hobson, R.J.1
Liu, Q.2
Watanabe, S.3
Jorgensen, E.M.4
-
29
-
-
73649108890
-
Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1
-
Jarman KE, Moretti PA, Zebol JR, Pitson SM. 2010. Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1. J Biol Chem 285: 483-492.
-
(2010)
J Biol Chem
, vol.285
, pp. 483-492
-
-
Jarman, K.E.1
Moretti, P.A.2
Zebol, J.R.3
Pitson, S.M.4
-
30
-
-
77749311463
-
Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans
-
doi: 10.1371/journal.pone.0008857
-
Kage-Nakadai E, Kobuna H, Kimura M, Gengyo-Ando K, Inoue T, Arai H, Mitani S. 2010. Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans. PLoS ONE 5: e8857. doi: 10.1371/journal.pone.0008857.
-
(2010)
PLoS ONE
, vol.5
-
-
Kage-Nakadai, E.1
Kobuna, H.2
Kimura, M.3
Gengyo-Ando, K.4
Inoue, T.5
Arai, H.6
Mitani, S.7
-
31
-
-
34247552132
-
Involvement of sphingosine-1-phosphate in gluta- mate secretion in hippocampal neurons
-
Kajimoto T, Okada T, Yu H, Goparaju SK, Jahangeer S, Nakamura S. 2007. Involvement of sphingosine-1-phosphate in gluta- mate secretion in hippocampal neurons. Mol Cell Biol 27: 3429-3440.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3429-3440
-
-
Kajimoto, T.1
Okada, T.2
Yu, H.3
Goparaju, S.K.4
Jahangeer, S.5
Nakamura, S.6
-
32
-
-
78650176947
-
Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus
-
Kanno T, Nishizaki T, Proia RL, Kajimoto T, Jahangeer S, Okada T, Nakamura S. 2010. Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus. Neuroscience 171: 973-980.
-
(2010)
Neuroscience
, vol.171
, pp. 973-980
-
-
Kanno, T.1
Nishizaki, T.2
Proia, R.L.3
Kajimoto, T.4
Jahangeer, S.5
Okada, T.6
Nakamura, S.7
-
33
-
-
33646426428
-
Sphingosine-1-phosphate activates BKCa channels indepen- dently of G protein-coupled receptor in human endothelial cells
-
10.1152/ajpcell.00353.2005
-
Kim MY, Liang GH, Kim JA, Kim YJ, Oh S, Suh SH. 2006. Sphingosine-1-phosphate activates BKCa channels indepen- dently of G protein-coupled receptor in human endothelial cells. Am J Physiol Cell Physiol 290: C1000-C1008. doi: 10.1152/ajpcell.00353.2005
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Kim, M.Y.1
Liang, G.H.2
Kim, J.A.3
Kim, Y.J.4
Oh, S.5
Suh, S.H.6
-
34
-
-
0033213254
-
Facilitation of synaptic transmission by EGL-30 Gqa and EGL-8 PLCb: DAG binding to UNC-13 is required to stimulate acetylcholine release
-
Lackner MR, Nurrish SJ, Kaplan JM. 1999. Facilitation of synaptic transmission by EGL-30 Gqa and EGL-8 PLCb: DAG binding to UNC-13 is required to stimulate acetylcholine release. Neuron 24: 335-346.
-
(1999)
Neuron
, vol.24
, pp. 335-346
-
-
Lackner, M.R.1
Nurrish, S.J.2
Kaplan, J.M.3
-
35
-
-
33747588567
-
Cellular signalling by sphingosine kinase and sphingosine 1-phosphate
-
Leclercq TM, Pitson SM. 2006. Cellular signalling by sphingosine kinase and sphingosine 1-phosphate. IUBMB Life 58: 467-472.
-
(2006)
IUBMB Life
, vol.58
, pp. 467-472
-
-
Leclercq, T.M.1
Pitson, S.M.2
-
36
-
-
34848904845
-
2+/ calmodulin-dependent protein kinase II modulates neurotransmitter release by activating BK channels at Caenorhabditis elegans neuromuscular junction
-
2+/ calmodulin-dependent protein kinase II modulates neurotransmitter release by activating BK channels at Caenorhabditis elegans neuromuscular junction. J Neurosci 27: 10404-10413.
-
(2007)
J Neurosci
, vol.27
, pp. 10404-10413
-
-
Liu, Q.1
Chen, B.2
Ge, Q.3
Wang, Z.W.4
-
37
-
-
33846941538
-
Ga(q)-coupled muscarinic acetylcholine receptors enhance nicotinic acetylcholine receptor signaling in Caenorhabditis elegans mating behavior
-
Liu Y, LeBoeuf B, Garcia LR. 2007. Ga(q)-coupled muscarinic acetylcholine receptors enhance nicotinic acetylcholine receptor signaling in Caenorhabditis elegans mating behavior. J Neurosci 27: 1411-1421.
-
(2007)
J Neurosci
, vol.27
, pp. 1411-1421
-
-
Liu, Y.1
Leboeuf, B.2
Garcia, L.R.3
-
38
-
-
58149390800
-
Kalirin-7 is required for synaptic structure and function
-
Ma XM, Kiraly DD, Gaier ED, Wang Y, Kim EJ, Levine ES, Eipper BA, Mains RE. 2008. Kalirin-7 is required for synaptic structure and function. J Neurosci 28: 12368-12382.
-
(2008)
J Neurosci
, vol.28
, pp. 12368-12382
-
-
Ma, X.M.1
Kiraly, D.D.2
Gaier, E.D.3
Wang, Y.4
Kim, E.J.5
Levine, E.S.6
Eipper, B.A.7
Mains, R.E.8
-
39
-
-
29044447583
-
UNC-13 interaction with syntaxin is required for synaptic transmission
-
Madison JM, Nurrish S, Kaplan JM. 2005. UNC-13 interaction with syntaxin is required for synaptic transmission. Curr Biol 15: 2236-2242.
-
(2005)
Curr Biol
, vol.15
, pp. 2236-2242
-
-
Madison, J.M.1
Nurrish, S.2
Kaplan, J.M.3
-
40
-
-
0033613833
-
Kalirin, a multifunctional PAM COOH-terminal domain interactor protein, affects cytoskeletal organization and ACTH secretion from AtT-20 cells
-
Mains RE, Alam MR, Johnson RC, Darlington DN, Back N, Hand TA, Eipper BA. 1999. Kalirin, a multifunctional PAM COOH-terminal domain interactor protein, affects cytoskeletal organization and ACTH secretion from AtT-20 cells. J Biol Chem 274: 2929-2937.
-
(1999)
J Biol Chem
, vol.274
, pp. 2929-2937
-
-
Mains, R.E.1
Alam, M.R.2
Johnson, R.C.3
Darlington, D.N.4
Back, N.5
Hand, T.A.6
Eipper, B.A.7
-
41
-
-
79151478184
-
Complexin has opposite effects on two modes of synaptic vesicle fusion
-
Martin JA, Hu Z, Fenz KM, Fernandez J, Dittman JS. 2011. Complexin has opposite effects on two modes of synaptic vesicle fusion. Curr Biol 21: 97-105.
-
(2011)
Curr Biol
, vol.21
, pp. 97-105
-
-
Martin, J.A.1
Hu, Z.2
Fenz, K.M.3
Fernandez, J.4
Dittman, J.S.5
-
42
-
-
0027991078
-
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from in- ternal stores via an inositol trisphosphate-independent pathway
-
Mattie M, Brooker G, Spiegel S. 1994. Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from in- ternal stores via an inositol trisphosphate-independent pathway. J Biol Chem 269: 3181-3188.
-
(1994)
J Biol Chem
, vol.269
, pp. 3181-3188
-
-
Mattie, M.1
Brooker, G.2
Spiegel, S.3
-
43
-
-
29944441832
-
Rho is a presynaptic activator of neurotransmitter release at pre- existing synapses in C. elegans
-
McMullan R, Hiley E, Morrison P, Nurrish SJ. 2006. Rho is a presynaptic activator of neurotransmitter release at pre- existing synapses in C. elegans. Genes Dev 20: 65-76.
-
(2006)
Genes Dev
, vol.20
, pp. 65-76
-
-
McMullan, R.1
Hiley, E.2
Morrison, P.3
Nurrish, S.J.4
-
44
-
-
0025942107
-
Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
-
Mello CC, Kramer JM, Stinchcomb D, Ambros V. 1991. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences. EMBO J 10: 3959-3970.
-
(1991)
EMBO J
, vol.10
, pp. 3959-3970
-
-
Mello, C.C.1
Kramer, J.M.2
Stinchcomb, D.3
Ambros, V.4
-
45
-
-
65249102170
-
Protection of C. elegans from anoxia by HYL-2 ceramide synthase
-
Menuz V, Howell KS, Gentina S, Epstein S, Riezman I, Fornallaz M. M, Hengartner MO, Gomez M, Riezman H, Martinou JC. 2009. Protection of C. elegans from anoxia by HYL-2 ceramide synthase. Science 324: 381-384.
-
(2009)
Science
, vol.324
, pp. 381-384
-
-
Menuz, V.1
Howell, K.S.2
Gentina, S.3
Epstein, S.4
Riezman, I.5
Fornallaz, M.M.6
Hengartner, M.O.7
Gomez, M.8
Riezman, H.9
Martinou, J.C.10
-
46
-
-
2642630721
-
2+ signalling by G-protein-coupled receptors
-
2+ signalling by G-protein-coupled receptors. EMBO J 17: 2830-2837.
-
(1998)
EMBO J
, vol.17
, pp. 2830-2837
-
-
Meyer, Z.H.D.1
Lass, H.2
Alemany, R.3
Laser, K.T.4
Neumann, E.5
Zhang, C.6
Schmidt, M.7
Rauen, U.8
Jakobs, K.H.9
van Koppen, C.J.10
-
47
-
-
28544437478
-
Essential role for sphingosine kinases in neural and vascular development
-
Mizugishi K, Yamashita T, Olivera A, Miller GF, Spiegel S, Proia RL. 2005. Essential role for sphingosine kinases in neural and vascular development. Mol Cell Biol 25: 11113-11121.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 11113-11121
-
-
Mizugishi, K.1
Yamashita, T.2
Olivera, A.3
Miller, G.F.4
Spiegel, S.5
Proia, R.L.6
-
48
-
-
70349935745
-
Nerve growth factor, sphingomyelins, and sensitization in sensory neurons
-
Nicol GD. 2008. Nerve growth factor, sphingomyelins, and sensitization in sensory neurons. Sheng Li Xue Bao 60: 603-604.
-
(2008)
Sheng Li Xue Bao
, vol.60
, pp. 603-604
-
-
Nicol, G.D.1
-
49
-
-
0033198830
-
Serotonin inhibition of synaptic transmission: Ga(0) decreases the abundance of UNC-13 at release sites
-
Nurrish S, Segalat L, Kaplan JM. 1999. Serotonin inhibition of synaptic transmission: Ga(0) decreases the abundance of UNC-13 at release sites. Neuron 24: 231-242.
-
(1999)
Neuron
, vol.24
, pp. 231-242
-
-
Nurrish, S.1
Segalat, L.2
Kaplan, J.M.3
-
50
-
-
56949105142
-
Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system
-
Okada T, Kajimoto T, Jahangeer S, Nakamura SI. 2009. Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. Cell Signal 21: 7-13.
-
(2009)
Cell Signal
, vol.21
, pp. 7-13
-
-
Okada, T.1
Kajimoto, T.2
Jahangeer, S.3
Nakamura, S.I.4
-
51
-
-
43049168797
-
Unraveling the complexities of sphingosine- 1-phosphate function: The mast cell model
-
Olivera A. 2008. Unraveling the complexities of sphingosine- 1-phosphate function: The mast cell model. Prostaglandins Other Lipid Mediat 86: 1-11.
-
(2008)
Prostaglandins Other Lipid Mediat
, vol.86
, pp. 1-11
-
-
Olivera, A.1
-
52
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera A, Spiegel S. 1993. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365: 557-560.
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
53
-
-
79955707303
-
Neuronal polarity in C. elegans
-
Ou CY, Shen K. 2011. Neuronal polarity in C. elegans. Dev Neurobiol 71: 554-566.
-
(2011)
Dev Neurobiol
, vol.71
, pp. 554-566
-
-
Ou, C.Y.1
Shen, K.2
-
55
-
-
59649100571
-
Snapin facilitates the synchronization of synaptic vesicle fusion
-
Pan PY, Tian JH, Sheng ZH. 2009. Snapin facilitates the synchronization of synaptic vesicle fusion. Neuron 61: 412-424.
-
(2009)
Neuron
, vol.61
, pp. 412-424
-
-
Pan, P.Y.1
Tian, J.H.2
Sheng, Z.H.3
-
56
-
-
67650215189
-
A network of G-protein signaling pathways control neuronal activity in C. elegans
-
Perez-Mansilla B, Nurrish S. 2009. A network of G-protein signaling pathways control neuronal activity in C. elegans. Adv Genet 65: 145-192.
-
(2009)
Adv Genet
, vol.65
, pp. 145-192
-
-
Perez-Mansilla, B.1
Nurrish, S.2
-
57
-
-
25444483556
-
Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways
-
doi: 10.1186/1465-9921-6-48
-
Pfaff M, Powaga N, Akinci S, Schutz W, Banno Y, Wiegand S, Kummer W, Wess J, Haberberger RV. 2005. Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways. Respir Res 6: 48. doi: 10.1186/1465-9921-6-48
-
(2005)
Respir Res
, vol.6
, pp. 48
-
-
Pfaff, M.1
Powaga, N.2
Akinci, S.3
Schutz, W.4
Banno, Y.5
Wiegand, S.6
Kummer, W.7
Wess, J.8
Haberberger, R.V.9
-
58
-
-
79551614173
-
Regulation of sphingosine kinase and sphingolipid signaling
-
Pitson SM. 2011. Regulation of sphingosine kinase and sphingolipid signaling. Trends Biochem Sci 36: 97-107.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 97-107
-
-
Pitson, S.M.1
-
59
-
-
0037147198
-
The nucleotide-binding site of human sphingosine kinase 1
-
Pitson SM, Moretti PA, Zebol JR, Zareie R, Derian CK, Darrow AL, Qi J, D'Andrea RJ, Bagley CJ, Vadas MA, et al. 2002. The nucleotide-binding site of human sphingosine kinase 1. J Biol Chem 277: 49545-49553.
-
(2002)
J Biol Chem
, vol.277
, pp. 49545-49553
-
-
Pitson, S.M.1
Moretti, P.A.2
Zebol, J.R.3
Zareie, R.4
Derian, C.K.5
Darrow, A.L.6
Qi, J.7
D'Andrea, R.J.8
Bagley, C.J.9
Vadas, M.A.10
-
60
-
-
0142105397
-
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation
-
Pitson SM, Moretti PA, Zebol JR, Lynn HE, Xia P, Vadas MA, Wattenberg BW. 2003. Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation. EMBO J 22: 5491-5500.
-
(2003)
EMBO J
, vol.22
, pp. 5491-5500
-
-
Pitson, S.M.1
Moretti, P.A.2
Zebol, J.R.3
Lynn, H.E.4
Xia, P.5
Vadas, M.A.6
Wattenberg, B.W.7
-
61
-
-
0024669454
-
Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis
-
Rand JB. 1989. Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis. Genetics 122: 73-80.
-
(1989)
Genetics
, vol.122
, pp. 73-80
-
-
Rand, J.B.1
-
62
-
-
0033361969
-
One GABA and two acetyl- choline receptors function at the C. elegans neuromuscular junction
-
Richmond JE, Jorgensen EM. 1999. One GABA and two acetyl- choline receptors function at the C. elegans neuromuscular junction. Nat Neurosci 2: 791-797.
-
(1999)
Nat Neurosci
, vol.2
, pp. 791-797
-
-
Richmond, J.E.1
Jorgensen, E.M.2
-
63
-
-
0033349884
-
UNC-13 is required for synaptic vesicle fusion in C. elegans
-
Richmond JE, Davis WS, Jorgensen EM. 1999. UNC-13 is required for synaptic vesicle fusion in C. elegans. Nat Neurosci 2: 959-964.
-
(1999)
Nat Neurosci
, vol.2
, pp. 959-964
-
-
Richmond, J.E.1
Davis, W.S.2
Jorgensen, E.M.3
-
64
-
-
0035913332
-
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
-
Richmond JE, Weimer RM, Jorgensen EM. 2001. An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412: 338-341.
-
(2001)
Nature
, vol.412
, pp. 338-341
-
-
Richmond, J.E.1
Weimer, R.M.2
Jorgensen, E.M.3
-
65
-
-
4544297305
-
Ceramidase regu- lates synaptic vesicle exocytosis and trafficking
-
Rohrbough J, Rushton E, Palanker L, Woodruff E, Matthies HJ, Acharya U, Acharya JK, Broadie K. 2004. Ceramidase regu- lates synaptic vesicle exocytosis and trafficking. J Neurosci 24: 7789-7803.
-
(2004)
J Neurosci
, vol.24
, pp. 7789-7803
-
-
Rohrbough, J.1
Rushton, E.2
Palanker, L.3
Woodruff, E.4
Matthies, H.J.5
Acharya, U.6
Acharya, J.K.7
Broadie, K.8
-
67
-
-
79851480014
-
Gaq and phospholipase C-b: Turn on, turn off, and do it fast
-
doi: 10.1126/scisignal. 2001798
-
Ross EM. 2011. Gaq and phospholipase C-b: Turn on, turn off, and do it fast. Sci Signal 4: pe5. doi: 10.1126/scisignal. 2001798
-
(2011)
Sci Signal
, vol.4
, Issue.5
-
-
Ross, E.M.1
-
68
-
-
0242570882
-
The M3 muscarinic acetylcholine receptor expressed in HEK-293 cells signals to phospholipase D via G12 but not Gq-type G proteins: Regulators of G proteins as tools to dissect pertussis toxin-resistant G proteins in receptor-effector coupling
-
Rumenapp U, Asmus M, Schablowski H, Woznicki M, Han L, Jakobs KH, Fahimi-Vahid M, Michalek C, Wieland T, Schmidt M. 2001. The M3 muscarinic acetylcholine receptor expressed in HEK-293 cells signals to phospholipase D via G12 but not Gq-type G proteins: Regulators of G proteins as tools to dissect pertussis toxin-resistant G proteins in receptor-effector coupling. J Biol Chem 276: 2474-2479.
-
(2001)
J Biol Chem
, vol.276
, pp. 2474-2479
-
-
Rumenapp, U.1
Asmus, M.2
Schablowski, H.3
Woznicki, M.4
Han, L.5
Jakobs, K.H.6
Fahimi-Vahid, M.7
Michalek, C.8
Wieland, T.9
Schmidt, M.10
-
69
-
-
25844457390
-
Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells
-
Sarkar S, Maceyka M, Hait NC, Paugh SW, Sankala H, Milstien S, Spiegel S. 2005. Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells. FEBS Lett 579: 5313-5317.
-
(2005)
FEBS Lett
, vol.579
, pp. 5313-5317
-
-
Sarkar, S.1
Maceyka, M.2
Hait, N.C.3
Paugh, S.W.4
Sankala, H.5
Milstien, S.6
Spiegel, S.7
-
70
-
-
23144441321
-
Systematic analysis of genes required for synapse structure and function
-
Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual J-F, Hill DE, Vidal M, et al. 2005. Systematic analysis of genes required for synapse structure and function. Nature 436: 510-517.
-
(2005)
Nature
, vol.436
, pp. 510-517
-
-
Sieburth, D.1
Ch'ng, Q.2
Dybbs, M.3
Tavazoie, M.4
Kennedy, S.5
Wang, D.6
Dupuy, D.7
Rual, J.-F.8
Hill, D.E.9
Vidal, M.10
-
72
-
-
0034097714
-
Sphingosine 1-phosphate: A ligand for the EDG-1 family of G-protein-coupled receptors
-
Spiegel S. 2000. Sphingosine 1-phosphate: A ligand for the EDG-1 family of G-protein-coupled receptors. Ann N Y Acad Sci 905: 54-60.
-
(2000)
Ann N Y Acad Sci
, vol.905
, pp. 54-60
-
-
Spiegel, S.1
-
73
-
-
0031880177
-
Sphingosine-1-phosphate in cell growth and cell death
-
Spiegel S, Cuvillier O, Edsall LC, Kohama T, Menzeleev R, Olah Z, Olivera A, Pirianov G, Thomas DM, Tu Z, et al. 1998. Sphingosine-1-phosphate in cell growth and cell death. Ann N YAcadSci845: 11-18.
-
(1998)
Ann N YAcadSci
, vol.845
, pp. 11-18
-
-
Spiegel, S.1
Cuvillier, O.2
Edsall, L.C.3
Kohama, T.4
Menzeleev, R.5
Olah, Z.6
Olivera, A.7
Pirianov, G.8
Thomas, D.M.9
Tu, Z.10
-
74
-
-
30044452349
-
The mechanism of membrane targeting of human sphingosine kinase 1
-
Stahelin RV, Hwang JH, Kim JH, Park ZY, Johnson KR, Obeld LM, Cho W. 2005. The mechanism of membrane targeting of human sphingosine kinase 1. J Biol Chem 280: 43030-43038.
-
(2005)
J Biol Chem
, vol.280
, pp. 43030-43038
-
-
Stahelin, R.V.1
Hwang, J.H.2
Kim, J.H.3
Park, Z.Y.4
Johnson, K.R.5
Obeld, L.M.6
Cho, W.7
-
75
-
-
3142713002
-
The GAR-3 muscarinic receptor cooperates with calcium signals to regulate muscle contraction in the Caenorhabditis elegans pharynx
-
Steger KA, Avery L. 2004. The GAR-3 muscarinic receptor cooperates with calcium signals to regulate muscle contraction in the Caenorhabditis elegans pharynx. Genetics 167: 633-643.
-
(2004)
Genetics
, vol.167
, pp. 633-643
-
-
Steger, K.A.1
Avery, L.2
-
76
-
-
24344445483
-
The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans
-
Steven R, Zhang L, Culotti J, Pawson T. 2005. The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans. Genes Dev 19: 2016-2029.
-
(2005)
Genes Dev
, vol.19
, pp. 2016-2029
-
-
Steven, R.1
Zhang, L.2
Culotti, J.3
Pawson, T.4
-
77
-
-
33744951972
-
The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane
-
Sutherland CM, Moretti PA, Hewitt NM, Bagley CJ, Vadas MA, Pitson SM. 2006. The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane. J Biol Chem 281: 11693-11701.
-
(2006)
J Biol Chem
, vol.281
, pp. 11693-11701
-
-
Sutherland, C.M.1
Moretti, P.A.2
Hewitt, N.M.3
Bagley, C.J.4
Vadas, M.A.5
Pitson, S.M.6
-
78
-
-
64749096694
-
Ga(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors
-
Ter B. M, Danneberg K, Lichte K, Liphardt K, Ktistakis NT, Pitson SM, Hla T, Jakobs KH, Meyer Z.H.D. 2009. Ga(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors. Biochim Biophys Acta 1791: 357-370.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 357-370
-
-
Ter B., M.1
Danneberg, K.2
Lichte, K.3
Liphardt, K.4
Ktistakis, N.T.5
Pitson, S.M.6
Hla, T.7
Jakobs, K.H.8
Meyer, Z.H.D.9
-
79
-
-
4544224536
-
Early activation of sphingosine kinase in mast cells and recruitment to FceRI are mediated by its interaction with Lyn kinase
-
Urtz N, Olivera A, Bofill-Cardona E, Csonga R, Billich A, Mechtcheriakova D, Bornancin F, Woisetschlager M, Rivera J, Baumruker T. 2004. Early activation of sphingosine kinase in mast cells and recruitment to FceRI are mediated by its interaction with Lyn kinase. Mol Cell Biol 24: 8765-8777.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8765-8777
-
-
Urtz, N.1
Olivera, A.2
Bofill-Cardona, E.3
Csonga, R.4
Billich, A.5
Mechtcheriakova, D.6
Bornancin, F.7
Woisetschlager, M.8
Rivera, J.9
Baumruker, T.10
-
80
-
-
42949097579
-
An RNAi screen identifies genes that regulate GABA synapses
-
Vashlishan AB, Madison JM, Dybbs M, Bai J, Sieburth D, Ch'ng Q, Tavazoie M, Kaplan JM. 2008. An RNAi screen identifies genes that regulate GABA synapses. Neuron 58: 346-361.
-
(2008)
Neuron
, vol.58
, pp. 346-361
-
-
Vashlishan, A.B.1
Madison, J.M.2
Dybbs, M.3
Bai, J.4
Sieburth, D.5
Ch'ng, Q.6
Tavazoie, M.7
Kaplan, J.M.8
-
81
-
-
0141542671
-
Defects in synaptic vesicle docking in unc-18 mutants
-
Weimer RM, Richmond JE, Davis WS, Hadwiger G, Nonet ML, Jorgensen EM. 2003. Defects in synaptic vesicle docking in unc-18 mutants. Nat Neurosci 6: 1023-1030.
-
(2003)
Nat Neurosci
, vol.6
, pp. 1023-1030
-
-
Weimer, R.M.1
Richmond, J.E.2
Davis, W.S.3
Hadwiger, G.4
Nonet, M.L.5
Jorgensen, E.M.6
-
82
-
-
35948965619
-
Trio's Rho-specific GEF domain is the missing Ga q effector in C. elegans
-
Williams SL, Lutz S, Charlie NK, Vettel C, Ailion M, Coco C, Tesmer JJG, Jorgensen EM, Wieland T, Miller KG. 2007. Trio's Rho-specific GEF domain is the missing Ga q effector in C. elegans. Genes Dev 21: 2731-2746.
-
(2007)
Genes Dev
, vol.21
, pp. 2731-2746
-
-
Williams, S.L.1
Lutz, S.2
Charlie, N.K.3
Vettel, C.4
Ailion, M.5
Coco, C.6
Tesmer, J.J.G.7
Jorgensen, E.M.8
Wieland, T.9
Miller, K.G.10
-
84
-
-
79951923158
-
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors
-
Yonamine I, Bamba T, Nirala NK, Jesmin N, Kosakowska Cholody T, Nagashima K, Fukusaki E, Acharya JK, Acharya U. 2011. Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. J Cell Biol 192: 557-567.
-
(2011)
J Cell Biol
, vol.192
, pp. 557-567
-
-
Yonamine, I.1
Bamba, T.2
Nirala, N.K.3
Jesmin, N.4
Kosakowska, C.T.5
Nagashima, K.6
Fukusaki, E.7
Acharya, J.K.8
Acharya, U.9
|