Are long-range structural correlations behind the aggregration phenomena of polyglutamine diseases?

PLoS Computational Biology

Volumn 8, Issue 4, 2012, Pages

  Moradi, Mahmoud ^a   Babin, Volodymyr ^a   Roland, Christopher ^a   Sagui, Celeste ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; MOLECULAR DYNAMICS; NEURODEGENERATIVE DISEASES; PEPTIDES;

CONFORMATIONAL ENSEMBLE; DYNAMICS SIMULATION; HEXAPEPTIDES; LONG RANGE CORRELATIONS; POLYGLUTAMINE; POLYGLUTAMINE DISEASE; POLYPROLINE; PROPERTY; STATE OF THE ART; STRUCTURAL CORRELATION;

DIHEDRAL ANGLE;

MONOMER; POLYGLUTAMINE; PEPTIDE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CIS TRANS ISOMERISM; CONTROLLED STUDY; CORRELATION ANALYSIS; GAMMA TURN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; STATISTICAL MODEL; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DEGENERATIVE DISEASE; HUMAN; METABOLISM; MOLECULAR GENETICS; STATISTICS;

AMINO ACID SEQUENCE; ANIMALS; COMPUTER SIMULATION; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURODEGENERATIVE DISEASES; PEPTIDES; PROTEIN CONFORMATION; STATISTICS AS TOPIC;

EID: 84861121209     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002501     Document Type: Article

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