Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor

Environmental Health Perspectives

Volumn 113, Issue 1, 2005, Pages 83-87

  Hennig, Bernhard ^a,b   Reiterer, Gudrun ^b   Toborek, Michal ^c   Matveev, Sergey V ^c   Daugherty, Alan ^b   Smart, Eric ^c   Robertson, Larry W ^d  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

Atherosclerosis; Dietary fat; Gene expression; Lipid metabolism; PCB; Polychlorinated biphenyl; Vascular endothelial cells

Indexed keywords

CORN OIL; FATTY ACID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; OLIVE OIL; POLYCHLORINATED BIPHENYL; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; FAT INTAKE; FATTY ACID BLOOD LEVEL; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; GENE INDUCTION; INFLAMMATION; LIPID DIET; LIPID METABOLISM; LIPID TRANSPORT; LIVER LEVEL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; POLLUTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; DIET; DIETARY FATS; DRUG INTERACTIONS; ENVIRONMENTAL POLLUTANTS; MICE; POLYCHLORINATED BIPHENYLS; RECEPTORS, LDL;

EID: 12744262897     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7280     Document Type: Article

References (33)

1. Asais-Braesco V, Macaire JP, Bellenand P, Robertson LW, Pascal G. 1990. Effects of two prototypic polychlorinated biphenyls (PCBs) on lipid composition of rat liver and serum. J Nutr Biochem 1:350-354.
2. Bell FP, Iverson F, Arnold D, Vidmar TJ. 1994. Long-term effects of Aroclor 1254 (PCBs) on plasma lipid and carnitine concentrations in rhesus monkey. Toxicology 89:139-153.
3. Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can J Med Sci 37:911-917.
4. Daugherty A. 2002. Mouse models of atherosclerosis. Am J Med Sci 323:3-10.
5. Daugherty A, Manning MW, Cassis LA. 2000. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Invest 105:1605-1612.
6. Debry G, Pelletier X. 1991. Physiological importance of omega-3/omega-6 polyunsaturated fatty acids in man. An overview of still unresolved and controversial questions. Experientia 47:172-178.
7. Garthoff LH, Friedman L, Farber TM, Locke KK, Sobotka TJ, Green S, et al. 1977. Biochemical and cytogenetic effects in rats caused by short-term ingestion of Aroclor 1254 or Firemaster BP6. J Toxicol Environ Health 3:769-796.
8. Gustavsson P, Hogstedt C. 1997. A cohort study of Swedish capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs). Am J Ind Med 32:234-239.
9. Hay A, Tarrel J. 1997. Mortality of power workers exposed to phenoxy herbicides and polychlorinated biphenyls in waste transformer oil. Ann NY Acad Sci 837:138-156.
10. Hennig B, Hammock BD, Slim R, Toborek M, Saraswathi V, Robertson LW. 2002a. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. Int J Hyg Environ Health 205:95-102.
11. Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, et al. 2002b. Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicol Appl Pharmacol 181:174-183.
12. Hennig B, Slim R, Toborek M, Hammock B, Robertson LW. 2001b. PCBs and cardiovascular disease: endothelial cells as a target for PCB toxicity. In: PCBs: Recent Advances in Environmental Toxicity and Health Effects (Robertson LW, Hansen LG, eds). Lexington, KY:University Press of Kentucky, 211-220.
13. Hennig B, Toborek M. 2001. Nutrition and endothelial cell function: implications in atherosclerosis. Nutr Res 21:279-293.
14. Hennig B, Toborek M, McClain CJ. 2001a. High-energy nutrients, fatty acids and endothelial cell function: implications in atherosclerosis. J Am Coll Nutr 20:97-105.
15. Hennig B, Watkins BA. 1989. Linoleic acid and linolenic acid: effect on permeability properties of cultured endothelial cell monolayers. Am J Clin Nutr 49:301-305.
16. Hinton DE, Glaumann H, Trump BF. 1978. Studies on the cellular toxicity of polychlorinated biphenyls (PCBs). I. Effects of PCBs on microsomal enzymes and on synthesis and turnover of microsomal and cytoplasmic lipids. Virchows Arch B Cell Pathol 27:279-306.
17. Ishidate K, Yoshida M, Nakazawa Y. 1978. Effect of typical inducers of microsomal drug-metabolizing enzymes on phospholipid metabolism in rat liver. Biochem Pharmacol 27:2595-2603.
18. Jenke HS. 1985. Polychlorinated biphenyls interfere with the regulation of hydroxymethylglutaryl-coenzyme A reductase activity in rat liver via enzyme-lipid interaction and at the transcriptional level. Biochim Biophys Acta 837:85-93.
19. Jensen AA. 1989. Background levels in humans. In: Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products (Kimbrough RD, Jensen AA, eds). Amstardam:Elsevier Science, 345-364.
20. Kakela R, Hyvarinen H. 1999. Fatty acid alterations caused by PCBs (Aroclor 1242) and copper in adipose tissue around lymph nodes of mink. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 122:45-53.
21. Massaro M, De Caterina R. 2002. Vasculoprotective effects of oleic acid: epidemiological background and direct vascular antiatherogenic properties. Nutr Metab Cardiovasc Dis 12:42-51.
22. Matsusue K, Ishii Y, Ariyoshi N, Oguri K. 1999. A highly toxic coplanar polychlorinated biphenyl compound suppresses delta5 and delta6 desaturase activities which play key roles in arachidonic acid synthesis in rat liver. Chem Res Toxicol 12:1158-1165.
23. Reeves PG. 1997. Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr 127(5 suppl):838S-841S.
24. Robertson LW, Silberhorn EM, Glauert HP, Schwarz M, Buchmann A. 1991. Do structure-activity relationships for the acute toxicity of PCBs and PBBs also apply for induction of hepatocellular carcinoma? Environ Toxicol Chem 10:715-726.
25. Safe S. 1994. Polychlorinated biphenyls (PCBs)- environmental impact, biochemical and toxic responses and implications for risk assessment. Crit Rev Toxicol 24:87-149.
26. Silversand C, Haux C. 1997. Improved high-performance liquid chromatographic method for the separation and quantification of lipid classes: application to fish lipids. J Chromatogr B Biomed Sci Appl 703:7-14.
27. Slim R, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau CH, et al. 2001. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicol Appl Pharmacol 171:184-193.
28. Spector AA, Kaduce TL, Hoak JC, Fry GL. 1981. Utilization of arachidonic and linoleic acids by cultured human endothelial cells. J Clin Invest 68:1003-1011.
29. Toborek M, Lee YW, Garrido R, Kaiser S, Hennig B. 2002. Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells. Am J Clin Nutr 75:119-125.
30. Tokunaga S, Hirota Y, Kataoka K. 1999. Association between the results of blood test and blood PCB level of chronic Yusho patients twenty five years after the outbreak. Fukuoka Igaku Zasshi 90:157-161.
31. Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. 2003. Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. J Am Coll Nutr 22:502-510.
32. Wassermann M, Wassermann D, Cucos S, Miller HJ. 1979. World PCBs map: storage and effects in man and his biologic environment in the 1970s. Ann NY Acad Sci 320:69-124.
33. Williams RD, Wang E, Merrill AH Jr. 1984. Enzymology of long-chain base synthesis by liver: characterization of serine palmitoyltransferase in rat liver microsomes. Arch Biochem Biophys. 228:282-291.