Cytochrome P4501A1 is required for vascular dysfunction and hypertension induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicological Sciences

Volumn 117, Issue 2, 2010, Pages 537-546

  Kopf, Phillip G ^a   Scott, Jason A ^a   Agbor, Larry N ^a   Boberg, Jason R ^a   Elased, Khalid M ^b   Huwe, Janice K ^c   Walker, Mary K ^a,d  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin; Cytochrome P4501A1; Endothelial dysfunction; Hypertension; Reactive oxygen species

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; HYDROGEN PEROXIDE; LUCIGENIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; BLOOD PRESSURE MONITORING; CLINICAL EVALUATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG LIVER LEVEL; ENDOTHELIAL DYSFUNCTION; ENZYME INDUCTION; HEART; HYPERTENSION; KIDNEY; LUMINESCENCE; MESENTERY; MOUSE; NONHUMAN; TELEMETRY; VASODILATATION;

ANIMALS; AORTA; BLOOD PRESSURE; CYTOCHROME P-450 CYP1A1; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; ENDOTHELIUM, VASCULAR; ENVIRONMENTAL POLLUTANTS; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERTENSION; LIVER; MALE; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TETRACHLORODIBENZODIOXIN; VASODILATION;

MUS;

EID: 77956920406     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq218     Document Type: Article

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