The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells

Biochemical and Biophysical Research Communications

Volumn 316, Issue 3, 2004, Pages 659-665

  Ludwig, Antje ^a   Lorenz, Mario ^a   Grimbo, Nicole ^a   Steinle, Frederike ^a   Meiners, Silke ^a   Bartsch, Cornelia ^a   Stangl, Karl ^a   Baumann, Gert ^a   Stangl, Verena ^a  

^a Schwerpunkt Kardiologie   (Germany)

Author keywords

Adhesion molecules; Atherosclerosis; Cytokines; Tea catechins

Indexed keywords

CATECHIN; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; FLAVONOID; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; ATHEROGENESIS; CELL ADHESION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; TEA; UMBILICAL CORD; VEIN;

CATECHIN; CELL ADHESION; CELL LINE; COCULTURE TECHNIQUES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; E-SELECTIN; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; MONOCYTES; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TEA; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 1642329031     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.02.099     Document Type: Article

References (36)

1. McKay D.L., Blumberg J.B. The role of tea in human health: an update. Am. Coll. Nutr. 21:2002;1-13.
2. Balentine D.A., Wiseman S.A., Bouwens L.C. The chemistry of tea flavonoids. Crit. Rev. Food Sci. Nutr. 37:1997;693-704.
3. Miura Y., Chiba T., Tomita I., Koizumi H., Miura S., Umegaki K., Hara Y., Ikeda M., Tomita T. Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice. J. Nutr. 131:2001;27-32.
4. Hayek T., Fuhrman B., Vaya J., Rosenblat M., Belinky P., Coleman R., Elis A., Aviram M. Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation. Arterioscler. Thromb. Vasc. Biol. 17:1997;2744-2752.
5. Yang T.T., Koo M.W. Inhibitory effect of Chinese green tea on endothelial cell-induced LDL oxidation. Atherosclerosis. 148:2000;67-73.
6. Miura Y., Chiba T., Miura S., Tomita I., Umegaki K., Ikeda M., Tomida T. Green tea polyphenols (flavan 3-ols) prevent oxidative modification of low density lipoproteins: an ex vivo study in humans. J. Nutr. Biochem. 11:2000;216-222.
7. Cybulsky M.I., Gimbrone M.A. Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 251:1991;788-791.
8. Ross R. Atherosclerosis is an inflammatory disease. Am. Heart J. 138:1999;S419-S420.
9. Stangl V., Gunther C., Jarrin A., Bramlage P., Moobed M., Staudt A., Baumann G., Stangl K. Homocysteine inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion via nuclear factor-kappaB dependent pathway. Biochem. Biophys. Res. Commun. 280:2001;1093-1100.
10. Tsuchiya S., Yamabe M., Yamaguchi Y., Kobayashi Y., Konno T., Tada K. Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int. J. Cancer. 26:1980;171-176.
11. Dschietzig T., Richter C., Pfannenschmidt G., Bartsch C., Laule M., Baumann G., Stangl K. Dexamethasone inhibits stimulation of pulmonary endothelins by proinflammatory cytokines: possible involvement of a nuclear factor kappaB dependent mechanism. Intensive Care Med. 27:2001;751-756.
12. Cybulsky M.I., Iiyama K., Li H.et al. A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J. Clin. Invest. 107:2001;1255-1262.
13. Rohde L.E., Lee R.T., Rivero J., Jamacochian M., Arroyo L.H., Briggs W., Rifai N., Libby P., Creager M.A., Ridker P.M. Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 18:1998;1765-1770.
14. Cybulsky M.I., Gimbrone M. Endothelial-leukocyte adhesion molecules in acute inflammation and atherogenesis. Simionescu N., Simionescu M. Endothelial Cell Dysfunction. 1992;129-140 Plenum Press, New York, NY.
15. Rice-Evans C. Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans. Proc. Soc. Exp. Biol. Med. 220:1999;262-266.
16. Robak J., Gryglewski R.J. Flavonoids are scavengers of superoxide anions. Biochem. Pharmacol. 37:1988;837-841.
17. Diaz M.N., Frei B., Vita J.A., Keaney J.F. Jr. Antioxidants and atherosclerotic heart disease. N. Engl. J. Med. 337:1997;408-416.
18. Weber C., Erl W., Pietsch A., Strobel M., Zeigler-Heilbrock H.W.L., Weber P.C. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-κB mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler. Thromb. 14:1994;1665-1673.
19. Lenardo M.J., Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell. 58:1989;227-229.
20. Marui N., Offermann M.K., Swerlick R., Kunsch C., Rosen C.A., Ahmad M., Alexander R.W., Medford R.M. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1993;1866-1874.
21. Ahmad N., Gupta S., Mukhtar H. Green tea polyphenol epigallocatechin-3- gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells. Arch. Biochem. Biophys. 376:2000;338-346.
22. Masuda M., Suzui M., Lim J.T., Weinstein I.B. Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells. Clin. Cancer Res. 9:2003;3486-3491.
23. Cobb R.R., Felts K.A., Parry G.C., Mackman N. D609, a phosphatidylcholine-specific phospholipase C inhibitor, blocks interleukin-1 beta-induced vascular cell adhesion molecule 1 gene expression in human endothelial cells. Mol. Pharmacol. 49:1996;998-1004.
24. Wolle J., Hill R.R., Ferguson E., Devall L.J., Trivedi B.K., Newton R.S., Saxena U. Selective inhibition of tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression by a novel flavonoid. Lack of effect on transcription factor NF-kappa B. Arterioscler. Thromb. Vasc. Biol. 16:1996;1501-1508.
25. Sen C.K., Bagchi D. Regulation of inducible adhesion molecule expression in human endothelial cells by grape seed proanthocyanidin extract. Mol. Cell. Biochem. 216:2001;1-7.
26. Iademarco M.F., McQuillan J.J., Rosen G.D., Dean D.C. Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). J. Biol. Chem. 267:1992;16323-16329.
27. Neish A.S., Williams A.J., Palmer H.J., Whitley M.Z., Collins T. Functional analysis of the human vascular cell adhesion molecule 1 promoter. J. Exp. Med. 176:1992;1583-1593.
28. Neish A.S., Read M.A., Thanos D., Pine R., Maniatis T., Collins T. Endothelial interferon regulatory factor 1 cooperates with NF-kappa B as a transcriptional activator of vascular cell adhesion molecule 1. Mol. Cell. Biol. 15:1995;2558-2569.
29. Neish A.S., Khachigian L.M., Park A., Baichwal V.R., Collins T. Sp1 is a component of the cytokine-inducible enhancer in the promoter of vascular cell adhesion molecule-1. J. Biol. Chem. 270:1995;28903-28909.
30. ′ -regulatory region. Induction by cytokines and phorbol ester J. Immunol. 147:1991;2777-2786.
31. Collins T., Read M.A., Neish A.S., Whitley M.Z., Thanos D., Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J. 10:1995;899-909.
32. Umetani M., Nakao H., Doi T., Iwasaki A., Ohtaka M., Nagoya T., Mataki C., Hamakubo T., Kodama T. A novel cell adhesion inhibitor, K-7174, reduces the endothelial VCAM-1 induction by inflammatory cytokines, acting through the regulation of GATA. Biochem. Biophys. Res. Commun. 272:2000;370-374.
33. Yamaguchi M., Suwa H., Miyasaka M., Kumada K. Selective inhibition of vascular cell adhesion molecule-1 expression by verapamil in human vascular endothelial cells. Transplantation. 63:1997;759-764.
34. Zapolska-Downar D., Zapolski-Downar A., Markiewski M., Ciechanowicz A., Kaczmarczyk M., Naruszewicz M. Selective inhibition by probucol of vascular cell adhesion molecule-1 (VCAM-1) expression in human vascular endothelial cells. Atherosclerosis. 155:2001;123-130.
35. Koga T., Meydani M. Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells. Am. J. Clin. Nutr. 73:2001;941-948.
36. Murase T., Kume N., Hase T., Shibuya Y., Nishizawa Y., Tokimitsu I., Kita T. Gallates inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of leukocyte adhesion molecules in vascular endothelial cells. Arterioscler. Thromb. Vasc. Biol. 19:1999;1412-1420.