Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular cells

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 1821-1830

  Satou, Ryousuke ^a   Miyata, Kayoko ^a   Gonzalez Villalobos, Romer A ^b   Ingelfinger, Julie R ^c   Navar, L Gabriel ^a   Kobori, Hiroyuki ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Hypertension; Inflammation; Kidney

Indexed keywords

ANGIOTENSINOGEN; BETA ACTIN; GAMMA INTERFERON; INTERLEUKIN 6; JANUS KINASE; JANUS KINASE 2; MESSENGER RNA; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; INFLAMMATION; KIDNEY PROXIMAL TUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANGIOTENSINOGEN; ANIMALS; BASE SEQUENCE; CELL LINE, TRANSFORMED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERFERON-GAMMA; JANUS KINASES; KIDNEY TUBULES, PROXIMAL; PHOSPHORYLATION; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84860894249     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-195198     Document Type: Article

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