Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity

FASEB Journal

Volumn 26, Issue 4, 2012, Pages 1493-1505

  Zuo, Daming ^a,b,c   Yu, Xiaofei ^a,b   Guo, Chunqing ^a,b   Yi, Huanfa ^a,b   Chen, Xing ^d   Conrad, Daniel H ^a   Guo, Tai L ^a   Chen, Zhengliang ^c   Fisher, Paul B ^a,b   Subjeck, John R ^d   Wang, Xiang Yang ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

CpG ODN; Endocytosis; TLR9

Indexed keywords

BETA ACTIN; CELL RECEPTOR; CHAPERONE; CPG OLIGODEOXYNUCLEOTIDE; DNA; DNA BINDING PROTEIN; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 170; HEAT SHOCK PROTEIN 110; HEAT SHOCK PROTEIN 70; I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12P40; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DAMAGE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCYTOSIS; ENDOSOME; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION; INFECTION RESISTANCE; INNATE IMMUNITY; INTERNALIZATION; LISTERIA MONOCYTOGENES; MACROPHAGE; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ENDOCYTOSIS; ENDOSOMES; GLYCOPROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNITY, INNATE; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; MICE, INBRED STRAINS; MOLECULAR CHAPERONES; MYELOID DIFFERENTIATION FACTOR 88; OLIGODEOXYRIBONUCLEOTIDES; TOLL-LIKE RECEPTOR 9;

LISTERIA MONOCYTOGENES; MUS;

EID: 84860893195     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-197707     Document Type: Article

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