Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15824-15829

  Liu, Bei ^a   Dai, Jie ^a   Zheng, Hong ^a   Stoilova, Diliana ^a   Sun, Shaoli ^a   Li, Zihai ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL SURFACE RECEPTOR; GLYCOPROTEIN GP 96; HEAT SHOCK PROTEIN; INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BONE MARROW; CELL ACTIVATION; CELL COMPARTMENTALIZATION; CELL FUNCTION; CELL MATURATION; CELL SURFACE; CHIMERA; CONTROLLED STUDY; DENDRITIC CELL; ENDOPLASMIC RETICULUM; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TISSUE DISTRIBUTION; TISSUE INJURY; TRANSGENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIGENS, DIFFERENTIATION; ANTIGENS, NEOPLASM; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; DENDRITIC CELLS; ENDOPLASMIC RETICULUM; GENOTYPE; HEAT-SHOCK PROTEINS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTES;

ANIMALIA; MUS MUSCULUS;

EID: 0346734122     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2635458100     Document Type: Article

References (34)

1. Banchereau, J. & Steinman, R. M. (1998) Nature 392, 245-252.
2. Shortman, K. & Liu, Y. J. (2002) Nat. Rev. Immunol. 2, 151-161.
3. Steinman, R. M. & Nussenzweig, M. C. (2002) Proc. Natl. Acad. Sci. USA 99, 351-358.
4. Liu, K., Iyoda, T., Saternus, M., Kimura, Y., Inaba, K. & Steinman, R. M. (2002) J. Exp. Med. 196, 1091-1097.
5. Belz, G. T., Behrens, G. M., Smith, C. M., Miller, J. F., Jones, C., Lejon, K., Fathman, C. G., Mueller, S. N., Shortman, K., Carbone, F. R. & Heath, W. R. (2002) J. Exp. Med. 196, 1099-1104.
6. Janeway, C. A., Jr., & Medzhitov, R. (2002) Annu. Rev. Immunol. 20, 197-216.
7. Srivastava, P. K. (2002) Nat. Rev. Immunol. 2, 185-194.
8. Binder, R. J., Han, D. K. & Srivastava, P. K. (2000) Nat. Immunol. 1, 151-155.
9. Basu, S., Binder, R. J., Ramalingam, T. & Srivastava, P. K. (2001) Immunity 14, 303-313.
10. Vabulas, R. M., Braedel, S., Hilf, N., Singh-Jasuja, H., Herter, S., Ahmad-Nejad, P., Kirschning, C. J., Da Costa, C., Rammensee, H. G., Wagner, H. & Schild, H. (2002) J. Biol. Chem. 277, 20847-20853.
11. Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C., Ghosh, S. & Janeway, C. A., Jr. (1998) Mol. Cell 2, 253-258.
12. Martin, M. U. & Wesche, H. (2002) Biochim. Biophys. Acta 1592, 265-280.
13. Zheng, H., Dai, J., Stoilova, D. & Li, Z. (2001) J. Immunol. 167, 6731-6735.
14. Masutani, K., Akahoshi, M., Tsuruya, K., Tokumoto, M., Ninomiya, T., Kohsaka, T., Fukuda, K., Kanai, H., Nakashima, H., Otsuka, T. & Hirakata, H. (2001) Arthritis Rheum. 44, 2097-2106.
15. Basu, S., Binder, R. J., Suto, R., Anderson, K. M. & Srivastava, P. K. (2000) Int. Immunol. 12, 1539-1546.
16. Singh-Jasuja, H., Scherer, H. U., Hilf, N., Arnold-Schild, D., Rammensee, H. G., Toes, R. E. & Schild, H. (2000) Eur. J. Immunol. 30, 2211-2215.
17. Banerjee, P. P., Vinay, D. S., Mathew, A., Raje, M., Parekh, V., Prasad, D. V., Kumar, A., Mitra, D. & Mishra, G. C. (2002) J. Immunol. 169, 3507-3518.
18. Kawai, T., Adachi, O., Ogawa, T., Takeda, K. & Akira, S. (1999) Immunity II, 115-122.
19. Langenkamp, A., Messi, M., Lanzavecchia, A. & Sallusto, F. (2000) Nat. Immunol. 1, 311-316.
20. Schnare, M., Barton, G. M., Holt, A. C., Takeda, K., Akira, S. & Medzhitov, R. (2001) Nat. Immunol. 2, 947-950.
21. Medzhitov, R. (2001) Nat. Rev. Immunol. 1, 135-145.
22. Takeda, K., Kaisho, T. & Akira, S. (2003) Annu. Rev. Immunol. 21, 335-376.
23. Randow, F. & Seed, B. (2001) Nat. Cell Biol. 3, 891-896.
24. Reed, R. C., Berwin, B., Baker, J. P. & Nicchitta, C. V. (2003) J. Biol. Chem. 278, 31853-31860.
25. Tan, E. M., Cohen, A. S., Fries, J. F., Masi, A. T., McShane, D. J., Rothfield, N. F., Schaller, J. G., Talal, N. & Winchester, R. J. (1982) Arthritis Rheum. 25, 1271-1277.
26. Liu, B., DeFilippo, A. & Li, Z. (2002) Mol. Cancer Ther. 1, 1147-1151.
27. Erkeller-Yuksel, F. M., Isenberg, D. A., Dhillon, V. B., Latchman, D. S. & Lydyard, P. M. (1992) J. Autoimmun. 5, 803-814.
28. Shlomchik, M. J., Craft, J. E. & Mamula, M. J. (2001) Nat. Rev. Immunol. 1, 147-153.
29. Mehling, A., Loser, K., Varga, G., Metze, D., Luger, T. A., Schwarz, T., Grabbe, S. & Beissert, S. (2001) J. Exp. Med. 194, 615-628.
30. Leadbetter, E. A., Rifkin, I. R., Hohlbaum, A. M., Beaudette, B. C., Shlomchik, M. J. & Marshak-Rothstein, A. (2002) Nature 416, 603-607.
31. Blanco, P., Palucka, A. K., Gill, M., Pascual, V. & Banchereau, J. (2001) Science 294, 1540-1543.
32. Ludewig, B., Junt, T., Hengartner, H. & Zinkernagel, R. M. (2001) Curr. Opin. Immunol. 13, 657-662.
33. Shortman, K. & Heath, W. R. (2001) Nat. Immunol. 2, 988-989.
34. Walker, L. S. & Abbas, A. K. (2002) Nat. Rev. Immunol. 2, 11-19.