Activation of NK 1 receptors in the locus coeruleus induces analgesia through noradrenergic-mediated descending inhibition in a rat model of neuropathic pain

British Journal of Pharmacology

Volumn 166, Issue 3, 2012, Pages 1047-1057

  Muto, Y ^a   Sakai, A ^a   Sakamoto, A ^a   Suzuki, H ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

2 adrenoceptor; locus coeruleus; neuropathic pain; NK 1 receptor; noradrenaline; substance P

Indexed keywords

17ALPHA ETHYNYL 17BETA HYDROXY 5ALPHA ANDROSTANO[3,2 B]PYRIMIDO[1,2 A]BENZIMIDAZOLE; NEUROKININ 1 RECEPTOR; SUBSTANCE P; YOHIMBINE;

ALLODYNIA; ANALGESIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; FACILITATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCUS CERULEUS; NERVE COMPRESSION; NEUROPATHIC PAIN; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC NERVE; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SCIATIC NERVE INJURY; SIGNAL TRANSDUCTION; UPREGULATION;

ADRENERGIC NEURONS; ANALGESIA; ANDROSTANES; ANIMALS; BEHAVIOR, ANIMAL; BENZIMIDAZOLES; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; LOCUS COERULEUS; MALE; NEURAL INHIBITION; NEURALGIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; SPINAL CORD; SUBSTANCE P;

EID: 84860854736     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01820.x     Document Type: Article

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