A mass spectrometric approach for characterization of amyloid-β aggregates and identification of their post-translational modifications

Biochemistry

Volumn 51, Issue 18, 2012, Pages 3759-3766

  Tay, William M ^a   Bryant, Jennifer G ^a   Martin, Patricia K ^a   Nix, A Jeremy ^a   Cusack, Bernadette M ^a   Rosenberry, Terrone L ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; DIAGNOSTIC TOOLS; IMMUNOAFFINITY CHROMATOGRAPHY; IN-VIVO; ION MAPPING; LOW LEVEL; POST-TRANSLATIONAL MODIFICATIONS; PRECURSOR IONS; STRUCTURAL CHARACTERIZATION; THERAPEUTIC DRUGS; TOXIC AGENTS; TRANSGLUTAMINASES;

AFFINITY CHROMATOGRAPHY; AMINO ACIDS; GLYCOPROTEINS; IONS; MASS SPECTROMETRY; OLIGOMERS;

AGGREGATES;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-15]; AMYLOID BETA PROTEIN[1-19]; AMYLOID BETA PROTEIN[1-35]; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[20-34]; AMYLOID BETA PROTEIN[35-40]; AMYLOID BETA PROTEIN[4-11]; AMYLOID BETA PROTEIN[4-12]; AMYLOID BETA PROTEIN[4-13]; AMYLOID BETA PROTEIN[4-19]; METHIONINE; PEPSIN A; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME METABOLISM; IMMUNOAFFINITY CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRECURSOR ION MAPPING; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN PROCESSING; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; MASS SPECTROMETRY; PEPSIN A; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRANSGLUTAMINASES;

EID: 84860782237     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300316d     Document Type: Article

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