Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes

Genes and Nutrition

Volumn 7, Issue 2, 2012, Pages 307-318

  Toegel, Stefan ^a,b,c   Wu, Shengqian Q ^b   Otero, Miguel ^c   Goldring, Mary B ^c   Leelapornpisid, Pimporn ^d   Chiari, Catharina ^a   Kolb, Alexander ^a   Unger, Frank M ^b   Windhager, Reinhard ^a   Viernstein, Helmut ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

^d CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Caesalpinia sappan; Chondrocytes; Matrix metalloproteinase; NFkB; Osteoarthritis; Tissue inhibitors of MMP

Indexed keywords

CAESALPINIA SAPPAN EXTRACT; COLLAGENASE 3; GELATINASE A; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; NEUTROPHIL COLLAGENASE; PROTEIN P50; STROMELYSIN; SYNAPTOTAGMIN I; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR RELA;

ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL ISOLATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SPECIFICITY; ENZYME SYNTHESIS; EXPRESSION VECTOR; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ZYMOGRAPHY;

CAESALPINIA SAPPAN;

EID: 84860772136     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-011-0244-8     Document Type: Article

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