Doxorubicin-induced neurotoxicity is attenuated by a 43-kD protein from the leaves of Cajanus indicus L. via NF-κB and mitochondria dependent pathways

Free Radical Research

Volumn 46, Issue 6, 2012, Pages 785-798

  Pal, Sankhadeep ^a   Ahir, Manisha ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Antioxidant; Apoptosis; Cajanus indicus protein (CI protein); Cell survival; Doxorubicin; Oxidative stress

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATASE; AMINE OXIDASE (FLAVIN CONTAINING); APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BIOGENIC AMINE; BRAIN AMINE; CALCIUM ION; CASPASE 3; CASPASE 9; CYTOCHROME C; DOXORUBICIN; HERBACEOUS AGENT; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POTASSIUM ION; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SODIUM ION; VEGETABLE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DAMAGE; BRAIN TISSUE; CAJANUS; CAJANUS INDICUS; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DOSE RESPONSE; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CAJANUS; DOXORUBICIN; MALE; MICE; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PLANT EXTRACTS; PLANT LEAVES; PLANT PROTEINS; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

CAJANUS CAJAN;

EID: 84860719251     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2012.678841     Document Type: Article

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