Transforming growth factor-β1 (TGF-β1) driven epithelial to mesenchymal transition (EMT) is accentuated by tumour necrosis factor α (TNFα) via crosstalk between the SMAD and NF-κB pathways

Cancer Microenvironment

Volumn 5, Issue 1, 2012, Pages 45-57

  Borthwick, Lee A ^a   Gardner, Aaron ^a   De Soyza, Anthony ^a,b   Mann, Derek A ^a   Fisher, Andrew J ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

Author keywords

Cancer; Epithelial to mesenchymal transition; Fibrosis; Microenvironment; Transforming growth factor 1; Tumour necrosis factor

Indexed keywords

I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; LUNG CARCINOMA; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 84860629528     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-011-0080-9     Document Type: Article

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