Global gene expression in larval zebrafish (Danio rerio) exposed to selective serotonin reuptake inhibitors (fluoxetine and sertraline) reveals unique expression profiles and potential biomarkers of exposure

Environmental Pollution

Volumn 167, Issue , 2012, Pages 163-170

  Park, June Woo ^a,c   Heah, Tze Ping ^a   Gouffon, Julia S ^a   Henry, Theodore B ^a,b   Sayler, Gary S ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b UNIVERSITY OF PLYMOUTH   (United Kingdom)

^c Korea Institute of Toxicology   (South Korea)

Author keywords

Acetylcholinesterase; FKBP5; Fluoxetine; Microarray; Sertraline

Indexed keywords

ACETYLCHOLINESTERASE; AFFYMETRIX GENECHIP; BIOCHEMICAL PATHWAY; CHOLINESTERASE ACTIVITY; DANIO RERIO; EXPRESSION PROFILE; FK506-BINDING PROTEINS; FKBP5; FLUOXETINE; GENE CODING; GENE EXPRESSION LEVELS; GENE ONTOLOGY; MOLECULAR PATHWAYS; Q-RT-PCR; SELECTIVE SEROTONIN REUPTAKE INHIBITOR; SERTRALINE; STRESS RESPONSE; TRANSCRIPTOMES; ZEBRAFISH;

BIOMARKERS; GENES; MICROARRAYS;

TRANSCRIPTION;

CHOLINESTERASE; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 5; FLUOXETINE; SERTRALINE; TRANSCRIPTOME; UNCLASSIFIED DRUG;

BIOCHEMISTRY; BIOMARKER; CHEMICAL BINDING; CYPRINID; EXPERIMENTAL STUDY; GENE EXPRESSION; INHIBITOR; LARVAL DEVELOPMENT; PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC MARKER; LARVA; NONHUMAN; NUCLEOTIDE SEQUENCE; STRESS; ZEBRA FISH;

ANIMALS; BIOLOGICAL MARKERS; FLUOXETINE; GENE EXPRESSION; LARVA; SEROTONIN UPTAKE INHIBITORS; SERTRALINE; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 84860608548     PISSN: 02697491     EISSN: 18736424     Source Type: Journal    
DOI: 10.1016/j.envpol.2012.03.039     Document Type: Article

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