Animal models of multiple system atrophy

Neuroscience

Volumn 211, Issue , 2012, Pages 77-82

  Fernagut, P O ^a,b   Tison, F ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSTITUT DES MALADIES NEURODÉGÉNÉRATIVES   (France)

Author keywords

Alpha synuclein; Basal ganglia; Levodopa; Multiple system atrophy; Oligodendrocyte; Parkinsonism

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 NITROPROPIONIC ACID; ALPHA SYNUCLEIN; LEVODOPA; MYELIN BASIC PROTEIN; NEUROTOXIN; OXIDOPAMINE; QUINOLINIC ACID;

CEREBELLUM DISEASE; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DYSAUTONOMIA; HUMAN; INFERIOR OLIVE; MEDIAL FOREBRAIN BUNDLE; NEUROPATHOLOGY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OLIGODENDROGLIA; PARKINSONISM; PONTINE NUCLEUS; PRIORITY JOURNAL; PUTAMEN; REVIEW; ROTAROD TEST; SHY DRAGER SYNDROME; SUBSTANTIA NIGRA; TRANSGENIC ANIMAL;

ALPHA-SYNUCLEIN; ANIMALS; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; MULTIPLE SYSTEM ATROPHY; NERVE DEGENERATION; NEUROTOXINS; SUBSTANTIA NIGRA;

EID: 84860603741     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.09.044     Document Type: Review

References (42)

1. Benarroch E.E., Schmeichel A.M., Low P.A., Parisi J.E. Depletion of putative chemosensitive respiratory neurons in the ventral medullary surface in multiple system atrophy. Brain 2007, 130:469-475.
2. Desplats P., Lee H.J., Bae E.J., Patrick C., Rockenstein E., Crews L., Spencer B., Masliah E., Lee S.J. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A 2009, 106:13010-13015.
3. Fearnley J.M., Lees A.J. Striatonigral degeneration. A clinicopathological study. Brain 1990, 113(Pt 6):1823-1842.
4. Fernagut P.O., Barraud Q., Bezard E., Ghorayeb I., Tison F. Metabolic activity of the subthalamic nucleus in a primate model of l-dopa-unresponsive parkinsonism. Neurol Res 2010, 32:1050-1053.
5. Fernagut P.O., Diguet E., Bioulac B., Tison F. MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration. Exp Neurol 2004, 185:47-62.
6. Fernagut P.O., Diguet E., Jaber M., Bioulac B., Tison F. Dopamine transporter knock-out mice are hypersensitive to 3-nitropropionic acid-induced striatal damage. Eur J Neurosci 2002, 15:2053-2056.
7. Fernagut P.O., Diguet E., Stefanova N., Biran M., Wenning G.K., Canioni P., Bioulac B., Tison F. Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation. Neuroscience 2002, 114:1005-1017.
8. Flabeau O., Meissner W.G., Tison F. Multiple system atrophy: current and future approaches to management. Ther Adv Neurol Disord 2010, 3:249-263.
9. Ghorayeb I., Fernagut P.O., Aubert I., Bezard E., Poewe W., Wenning G.K., Tison F. Toward a primate model of l-dopa-unresponsive parkinsonism mimicking striatonigral degeneration. Mov Disord 2000, 15:531-536.
10. Ghorayeb I., Fernagut P.O., Hervier L., Labattu B., Bioulac B., Tison F. A "single toxin-double lesion" rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis. Neuroscience 2002, 115:533-546.
11. Ghorayeb I., Fernagut P.O., Stefanova N., Wenning G.K., Bioulac B., Tison F. Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. Neurosci Lett 2002, 335:34-38.
12. Ghorayeb I., Puschban Z., Fernagut P.O., Scherfler C., Rouland R., Wenning G.K., Tison F. Simultaneous intrastriatal 6-hydroxydopamine and quinolinic acid injection: a model of early-stage striatonigral degeneration. Exp Neurol 2001, 167:133-147.
13. Gilman S., Low P.A., Quinn N., Albanese A., Ben-Shlomo Y., Fowler C.J., Kaufmann H., Klockgether T., Lang A.E., Lantos P.L., Litvan I., Mathias C.J., Oliver E., Robertson D., Schatz I., Wenning G.K. Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci 1999, 163:94-98.
14. Gilman S., Wenning G.K., Low P.A., Brooks D.J., Mathias C.J., Trojanowski J.Q., Wood N.W., Colosimo C., Dürr A., Fowler C.J., Kaufmann H., Klockgether T., Lees A., Poewe W., Quinn N., Revesz T., Robertson D., Sandroni P., Seppi K., Vidailhet M. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008, 71:670-676.
15. Hara K., Momose Y., Tokiguchi S., Shimohata M., Terajima K., Onodera O., Kakita A., Yamada M., Takahashi H., Hirasawa M., Mizuno Y., Ogata K., Goto J., Kanazawa I., Nishizawa M., Tsuji S. Multiplex families with multiple system atrophy. Arch Neurol 2007, 64:545-551.
16. Hughes A.J., Colosimo C., Kleedorfer B., Daniel S.E., Lees A.J. The dopaminergic response in multiple system atrophy. J Neurol Neurosurg Psychiatry 1992, 55:1009-1013.
17. Kahle P.J., Neumann M., Ozmen L., Muller V., Jacobsen H., Spooren W., Fuss B., Mallon B., Macklin W.B., Fujiwara H., Hasegawa M., Iwatsubo T., Kretzschmar H.A., Haass C. Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes. EMBO Rep 2002, 3:583-588.
18. Kennedy P.G., Duchen L.W. A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome. J Neurol Neurosurg Psychiatry 1985, 48:1103-1106.
19. Lipp A., Sandroni P., Ahlskog J.E., Fealey R.D., Kimpinski K., Iodice V., Gehrking T.L., Weigand S.D., Sletten D.M., Gehrking J.A., Nickander K.K., Singer W., Maraganore D.M., Gilman S., Wenning G.K., Shults C.W., Low P.A. Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure. Arch Neurol 2009, 66:742-750.
20. Miller D.W., Johnson J.M., Solano S.M., Hollingsworth Z.R., Standaert D.G., Young A.B. Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia. J Neural Transm 2005, 112:1613-1624.
21. Reynolds D.S., Carter R.J., Morton A.J. Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease. J Neurosci 1998, 18:10116-10127.
22. Scherfler C., Puschban Z., Ghorayeb I., Goebel G.P., Tison F., Jellinger K., Poewe W., Wenning G.K. Complex motor disturbances in a sequential double lesion rat model of striatonigral degeneration (multiple system atrophy). Neuroscience 2000, 99:43-54.
23. Scholz S.W., Houlden H., Schulte C., Sharma M., Li A., Berg D., Melchers A., Paudel R., Gibbs J.R., Simon-Sanchez J., Paisan-Ruiz C., Bras J., Ding J., Chen H., Traynor B.J., Arepalli S., Zonozi R.R., Revesz T., Holton J., Wood N., Lees A., Oertel W., Wüllner U., Goldwurm S., Pellecchia M.T., Illig T., Riess O., Fernandez H.H., Rodriguez R.L., Okun M.S., Poewe W., Wenning G.K., Hardy J.A., Singleton A.B., Del Sorbo F., Schneider S., Bhatia K.P., Gasser T. SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol 2009, 65:610-614.
24. Schrag A., Wenning G.K., Quinn N., Ben-Shlomo Y. Survival in multiple system atrophy. Mov Disord 2008, 23:294-296.
25. Schwarzacher S.W., Rub U., Deller T. Neuroanatomical characteristics of the human pre-Botzinger complex and its involvement in neurodegenerative brainstem diseases. Brain 2011, 134:24-35.
26. Shults C.W., Rockenstein E., Crews L., Adame A., Mante M., Larrea G., Hashimoto M., Song D., Iwatsubo T., Tsuboi K., Masliah E. Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci 2005, 25:10689-10699.
27. Spillantini M.G., Crowther R.A., Jakes R., Cairns N.J., Lantos P.L., Goedert M. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett 1998, 251:205-208.
28. Stefanova N., Lundblad M., Tison F., Poewe W., Cenci M.A., Wenning G.K. Effects of pulsatile l-DOPA treatment in the double lesion rat model of striatonigral degeneration (multiple system atrophy). Neurobiol Dis 2004, 15:630-639.
29. Stefanova N., Puschban Z., Fernagut P.O., Brouillet E., Tison F., Reindl M., Jellinger K.A., Poewe W., Wenning G.K. Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy). Acta Neuropathol 2003, 106:157-166.
30. Stefanova N., Reindl M., Neumann M., Haass C., Poewe W., Kahle P.J., Wenning G.K. Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy. Am J Pathol 2005, 166:869-876.
31. Stemberger S., Poewe W., Wenning G.K., Stefanova N. Targeted overexpression of human alpha-synuclein in oligodendroglia induces lesions linked to MSA-like progressive autonomic failure. Exp Neurol 2010, 224:459-464.
32. Tada M., Kakita A., Toyoshima Y., Onodera O., Ozawa T., Morita T., Nishizawa M., Takahashi H. Depletion of medullary serotonergic neurons in patients with multiple system atrophy who succumbed to sudden death. Brain 2009, 132:1810-1819.
33. Tison F., Wenning G.K., Daniel S.E., Quinn N. The pathophysiology of parkinsonism in multiple system atrophy. Eur J Neurol 1995, 2:435-444.
34. Tison F., Yekhlef F., Chrysostome V., Sourgen C. Prevalence of multiple system atrophy. Lancet 2000, 355:495-496.
35. Ubhi K., Lee P.H., Adame A., Inglis C., Mante M., Rockenstein E., Stefanova N., Wenning G.K., Masliah E. Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res 2009, 87:2728-2739.
36. Ubhi K., Rockenstein E., Mante M., Inglis C., Adame A., Patrick C., Whitney K., Masliah E. Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci 2010, 30:6236-6246.
37. Vidal J.S., Vidailhet M., Derkinderen P., Tzourio C., Alpérovitch A. Familial aggregation in atypical Parkinson's disease: a case control study in multiple system atrophy and progressive supranuclear palsy. J Neurol 2010, 257:1388-1393.
38. Waldner R., Puschban Z., Scherfler C., Seppi K., Jellinger K., Poewe W., Wenning G.K. No functional effects of embryonic neuronal grafts on motor deficits in a 3-nitropropionic acid rat model of advanced striatonigral degeneration (multiple system atrophy). Neuroscience 2001, 102:581-592.
39. Wenning G.K., Granata R., Laboyrie P.M., Quinn N.P., Jenner P., Marsden C.D. Reversal of behavioural abnormalities by fetal allografts in a novel rat model of striatonigral degeneration. Mov Disord 1996, 11:522-532.
40. Wenning G.K., Tison F., Elliott L., Quinn N.P., Daniel S.E. Olivopontocerebellar pathology in multiple system atrophy. Mov Disord 1996, 11:157-162.
41. Wullner U., Abele M., Schmitz-Huebsch T., Wilhelm K., Benecke R., Deuschl G., Klockgether T. Probable multiple system atrophy in a German family. J Neurol Neurosurg Psychiatry 2004, 75:924-925.
42. Yazawa I., Giasson B.I., Sasaki R., Zhang B., Joyce S., Uryu K., Trojanowski J.Q., Lee V.M. Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration. Neuron 2005, 45:847-859.