-
1
-
-
77953202722
-
Epidemiology and prognosis of epilepsy
-
Shorvon S, Perucca E, Engel J (Eds). Wiley-Blackwell, NJ, USA
-
Forsgren L, Hesdorffer D. Epidemiology and prognosis of epilepsy. In: The Treatment of Epilepsy. Shorvon S, Perucca E, Engel J (Eds). Wiley-Blackwell, NJ, USA, 21-31 (2009)
-
(2009)
Treatment of Epilepsy
, pp. 21-31
-
-
Forsgren, L.1
Hesdorffer, D.2
-
2
-
-
0027152087
-
Incidence of epilepsy and unprovoked seizures in Rochester
-
Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 34(3), 453-468 (1993)
-
(1993)
Minnesota: 1935-1984. Epilepsia
, vol.34
, Issue.3
, pp. 453-468
-
-
Hauser, W.A.1
Annegers, J.F.2
Kurland, L.T.3
-
3
-
-
79954622504
-
The pharmacological treatment of epilepsy in adults
-
Perucca E, Tomson T. The pharmacological treatment of epilepsy in adults. Lancet Neurol. 10(5), 446-456 (2011)
-
(2011)
Lancet Neurol.
, vol.10
, Issue.5
, pp. 446-456
-
-
Perucca, E.1
Tomson, T.2
-
4
-
-
33947241772
-
The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: An unblinded randomised controlled trial
-
Marson AG, Al-Kharusi AM, Alwaidh M et al. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: An unblinded randomised controlled trial. Lancet 369(9566), 1000-1015 (2007)
-
(2007)
Lancet
, vol.369
, Issue.9566
, pp. 1000-1015
-
-
Marson, A.G.1
Al-Kharusi, A.M.2
Alwaidh, M.3
-
5
-
-
84860553046
-
Patterns of treatment response in newly diagnosed epilepsy
-
Brodie M, Barry SJ, Bamagous G, Norrie J, Kwan P. Patterns of treatment response in newly diagnosed epilepsy. Epilepsia 52(Suppl. 6), 10 (2011)
-
(2011)
Epilepsia
, vol.52
, Issue.SUPPL. 6
, pp. 10
-
-
Brodie, M.1
Barry, S.J.2
Bamagous, G.3
Norrie, J.4
Kwan, P.5
-
6
-
-
0034598762
-
Early identification of refractory epilepsy
-
Kwan P, Brodie MJ. Early identification of refractory epilepsy. N. Engl. J. Med. 342(5), 314-319 (2000)
-
(2000)
N. Engl. J. Med.
, vol.342
, Issue.5
, pp. 314-319
-
-
Kwan, P.1
Brodie, M.J.2
-
7
-
-
38149000779
-
The neurobehavioural comorbidities of epilepsy: Can a natural history be developed
-
Hermann B, Seidenberg M, Jones J. The neurobehavioural comorbidities of epilepsy: Can a natural history be developed? Lancet Neurol. 7(2), 151-160 (2008)
-
(2008)
Lancet Neurol.
, vol.7
, Issue.2
, pp. 151-160
-
-
Hermann, B.1
Seidenberg, M.2
Jones, J.3
-
8
-
-
34447307119
-
Epilepsy and risk of suicide: A population-based case-control study
-
Christensen J, Vestergaard M, Mortensen PB, Sidenius P, Agerbo E. Epilepsy and risk of suicide: A population-based case-control study. Lancet Neurol. 6(8), 693-698 (2007)
-
(2007)
Lancet Neurol.
, vol.6
, Issue.8
, pp. 693-698
-
-
Christensen, J.1
Vestergaard, M.2
Mortensen, P.B.3
Sidenius, P.4
Agerbo, E.5
-
9
-
-
53649103661
-
Sudden unexpected death in epilepsy: Current knowledge and future directions
-
Tomson T, Nashef L, Ryvlin P. Sudden unexpected death in epilepsy: Current knowledge and future directions. Lancet Neurol. 7(11), 1021-1031 (2008)
-
(2008)
Lancet Neurol.
, vol.7
, Issue.11
, pp. 1021-1031
-
-
Tomson, T.1
Nashef, L.2
Ryvlin, P.3
-
11
-
-
78751488401
-
Mechanisms of epileptogenesis and potential treatment targets
-
Pitkanen A, Lukasiuk K. Mechanisms of epileptogenesis and potential treatment targets. Lancet Neurol. 10(2), 173-186 (2011)
-
(2011)
Lancet Neurol.
, vol.10
, Issue.2
, pp. 173-186
-
-
Pitkanen, A.1
Lukasiuk, K.2
-
12
-
-
80155204701
-
-
Shorvon S, Perucca E, Engel J (Eds). Wiley-Blackwell, NJ, USA
-
Mansbach H, Baulac M. Retigabine. In: The Treatment of Epilepsy. Shorvon S, Perucca E, Engel J (Eds). Wiley-Blackwell, NJ, USA, 637-646 (2009)
-
(2009)
Treatment of Epilepsy
, pp. 637-646
-
-
Mansbach, H.1
Baulac M. Retigabine2
-
13
-
-
0033916576
-
Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine
-
Main MJ, Cryan JE, Dupere JR, Cox B, Clare JJ, Burbidge SA. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine. Mol. Pharmacol. 58(2), 253-262 (2000)
-
(2000)
Mol. Pharmacol.
, vol.58
, Issue.2
, pp. 253-262
-
-
Main, M.J.1
Cryan, J.E.2
Dupere, J.R.3
Cox, B.4
Clare, J.J.5
Burbidge, S.A.6
-
14
-
-
0033862433
-
Retigabine, a novel anticonvulsant, enhances activation of KCNQ2/Q3 potassium channels
-
Wickenden AD, Yu W, Zou A, Jegla T, Wagoner PK. Retigabine, a novel anticonvulsant, enhances activation of KCNQ2/Q3 potassium channels. Mol. Pharmacol. 58(3), 591-600 (2000)
-
(2000)
Mol. Pharmacol.
, vol.58
, Issue.3
, pp. 591-600
-
-
Wickenden, A.D.1
Yu, W.2
Zou, A.3
Jegla, T.4
Wagoner, P.K.5
-
15
-
-
0031001337
-
Control of m-current
-
Marrion NV. Control of M-current. Annu. Rev. Physiol. 59, 483-504 (1997)
-
(1997)
Annu. Rev. Physiol.
, vol.59
, pp. 483-504
-
-
Marrion, N.V.1
-
16
-
-
73449119314
-
Voltage-gated potassium channels as therapeutic targets
-
Wulff H, Castle NA, Pardo LA. Voltage-gated potassium channels as therapeutic targets. Nat. Rev. Drug Discov. 8(12), 982-1001 (2009)
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, Issue.12
, pp. 982-1001
-
-
Wulff, H.1
Castle, N.A.2
Pardo, L.A.3
-
17
-
-
17344372328
-
A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns
-
Singh NA, Charlier C, Stauffer D et al. A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns. Nat. Genet. 18(1), 25-29 (1998)
-
(1998)
Nat. Genet.
, vol.18
, Issue.1
, pp. 25-29
-
-
Singh, N.A.1
Charlier, C.2
Stauffer, D.3
-
18
-
-
0032483972
-
KCNQ2 and KCNQ3 potassium channel subunits: Molecular correlates of the M-channel
-
Wang HS, Pan Z, Shi W et al. KCNQ2 and KCNQ3 potassium channel subunits: Molecular correlates of the M-channel. Science 282(5395), 1890-1893 (1998)
-
(1998)
Science
, vol.282
, Issue.5395
, pp. 1890-1893
-
-
Wang, H.S.1
Pan, Z.2
Shi, W.3
-
19
-
-
15744400656
-
The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate
-
Wuttke TV, Seebohm G, Bail S, Maljevic S, Lerche H. The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate. Mol. Pharmacol. 67(4), 1009-1017 (2005)
-
(2005)
Mol. Pharmacol.
, vol.67
, Issue.4
, pp. 1009-1017
-
-
Wuttke, T.V.1
Seebohm, G.2
Bail, S.3
Maljevic, S.4
Lerche, H.5
-
20
-
-
0029969951
-
D-23129: A new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures
-
Rostock A, Tober C, Rundfeldt C et al. D-23129: A new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures. Epilepsy Res. 23(3), 211-223 (1996)
-
(1996)
Epilepsy Res.
, vol.23
, Issue.3
, pp. 211-223
-
-
Rostock, A.1
Tober, C.2
Rundfeldt, C.3
-
21
-
-
0029891002
-
D-23129: A potent anticonvulsant in the amygdala kindling model of complex partial seizures
-
Tober C, Rostock A, Rundfeldt C, Bartsch R. D-23129: A potent anticonvulsant in the amygdala kindling model of complex partial seizures. Eur. J. Pharmacol. 303(3), 163-169 (1996)
-
(1996)
Eur. J. Pharmacol.
, vol.303
, Issue.3
, pp. 163-169
-
-
Tober, C.1
Rostock, A.2
Rundfeldt, C.3
Bartsch, R.4
-
22
-
-
58149237124
-
Antiepileptogenic and anti-ictogenic effects of retigabine under conditions of rapid kindling: An ontogenic study
-
Mazarati A, Wu J, Shin D, Kwon YS, Sankar R. Antiepileptogenic and anti-ictogenic effects of retigabine under conditions of rapid kindling: An ontogenic study. Epilepsia 49(10), 1777-1786 (2008)
-
(2008)
Epilepsia
, vol.49
, Issue.10
, pp. 1777-1786
-
-
Mazarati, A.1
Wu, J.2
Shin, D.3
Kwon, Y.S.4
Sankar, R.5
-
23
-
-
57849141134
-
Progress report on new antiepileptic drugs: A summary of the ninth Eilat Conference (EILAT IX)
-
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: A summary of the ninth Eilat Conference (EILAT IX). Epilepsy Res. 83(1), 1-43 (2009)
-
(2009)
Epilepsy Res.
, vol.83
, Issue.1
, pp. 1-43
-
-
Bialer, M.1
Johannessen, S.I.2
Levy, R.H.3
Perucca, E.4
Tomson, T.5
White, H.S.6
-
24
-
-
0036152375
-
Multiple-dose, linear, dose-proportional pharmacokinetics of retigabine in healthy volunteers
-
Ferron GM, Paul J, Fruncillo R et al. Multiple-dose, linear, dose-proportional pharmacokinetics of retigabine in healthy volunteers. J. Clin. Pharmacol. 42(2), 175-182 (2002)
-
(2002)
J. Clin. Pharmacol.
, vol.42
, Issue.2
, pp. 175-182
-
-
Ferron, G.M.1
Paul, J.2
Fruncillo, R.3
-
25
-
-
0037660846
-
Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects
-
Ferron GM, Patat A, Parks V, Rolan P, Troy SM. Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects. Br. J. Clin. Pharmacol. 56(1), 39-45 (2003)
-
(2003)
Br. J. Clin. Pharmacol.
, vol.56
, Issue.1
, pp. 39-45
-
-
Ferron, G.M.1
Patat, A.2
Parks, V.3
Rolan, P.4
Troy, S.M.5
-
26
-
-
0038293217
-
Pharmacokinetic interaction between retigabine and lamotrigine in healthy subjects
-
Hermann R, Knebel NG, Niebch G, Richards L, Borlak J, Locher M. Pharmacokinetic interaction between retigabine and lamotrigine in healthy subjects. Eur. J. Clin. Pharmacol. 58(12), 795-802 (2003)
-
(2003)
Eur. J. Clin. Pharmacol.
, vol.58
, Issue.12
, pp. 795-802
-
-
Hermann, R.1
Knebel, N.G.2
Niebch, G.3
Richards, L.4
Borlak, J.5
Locher, M.6
-
27
-
-
0037261396
-
Effects of age and sex on the disposition of retigabine
-
Hermann R, Ferron GM, Erb K et al. Effects of age and sex on the disposition of retigabine. Clin. Pharmacol. Ther. 73(1), 61-70 (2003)
-
(2003)
Clin. Pharmacol. Ther.
, vol.73
, Issue.1
, pp. 61-70
-
-
Hermann, R.1
Ferron, G.M.2
Erb, K.3
-
28
-
-
34247252905
-
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures
-
Porter RJ, Partiot A, Sachdeo R, Nohria V, Alves WM. Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures. Neurology 68(15), 1197-1204 (2007)
-
(2007)
Neurology
, vol.68
, Issue.15
, pp. 1197-1204
-
-
Porter, R.J.1
Partiot, A.2
Sachdeo, R.3
Nohria, V.4
Alves, W.M.5
-
29
-
-
78649984382
-
Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy
-
Brodie MJ, Lerche H, Gil-Nagel A et al. Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy. Neurology 75(20), 1817-1824 (2010)
-
(2010)
Neurology
, vol.75
, Issue.20
, pp. 1817-1824
-
-
Brodie, M.J.1
Lerche, H.2
Gil-Nagel, A.3
-
30
-
-
79955592696
-
Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy
-
French JA, Abou-Khalil BW, Leroy RF et al. Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy. Neurology 76(18), 1555-1563 (2011)
-
(2011)
Neurology
, vol.76
, Issue.18
, pp. 1555-1563
-
-
French, J.A.1
Abou-Khalil, B.W.2
Leroy, R.F.3
-
31
-
-
79951683602
-
Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-Analysis
-
Rheims S, Perucca E, Cucherat M, Ryvlin P. Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-Analysis. Epilepsia 52(2), 219-233 (2011)
-
(2011)
Epilepsia
, vol.52
, Issue.2
, pp. 219-233
-
-
Rheims, S.1
Perucca, E.2
Cucherat, M.3
Ryvlin, P.4
-
32
-
-
34447305538
-
Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs
-
Gazzola DM, Balcer LJ, French JA. Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs. Epilepsia 48(7), 1303-1307 (2007)
-
(2007)
Epilepsia
, vol.48
, Issue.7
, pp. 1303-1307
-
-
Gazzola, D.M.1
Balcer, L.J.2
French, J.A.3
-
33
-
-
84860551269
-
Long-term maintenance of efficacy with ezogabine (retigabine) 600-1200 mg/day: An assessment of three open-label extension studies over 12 months
-
Burdette DE, Porter RJ, Lee WJK, Hall S, DeRossett SE. Long-term maintenance of efficacy with ezogabine (retigabine) 600-1200 mg/day: An assessment of three open-label extension studies over 12 months. Neurology 76(9), A376-A377 (2011)
-
(2011)
Neurology
, vol.76
, Issue.9
-
-
Burdette, D.E.1
Porter, R.J.2
Lee, W.J.K.3
Hall, S.4
DeRossett, S.E.5
-
34
-
-
84860572234
-
Seizure-free rates in patients receiving long-term open-label ezogabine (retigabine) 600-1200 mg/day
-
Abou-Khalil B, Brodie M, Shaikh S, Lee WJK, Hall S, VanLandingham KE. Seizure-free rates in patients receiving long-term open-label ezogabine (retigabine) 600-1200 mg/day. Neurology 76(9), A289-A289 (2011)
-
(2011)
Neurology
, vol.76
, Issue.9
-
-
Abou-Khalil, B.1
Brodie, M.2
Shaikh, S.3
Lee, W.J.K.4
Hall, S.5
VanLandingham, K.E.6
-
35
-
-
36148983791
-
Likelihood of seizure remission in an adult population with refractory epilepsy
-
Callaghan BC, Anand K, Hesdorffer D, Hauser WA, French JA. Likelihood of seizure remission in an adult population with refractory epilepsy. Ann. Neurol. 62(4), 382-389 (2007)
-
(2007)
Ann. Neurol.
, vol.62
, Issue.4
, pp. 382-389
-
-
Callaghan, B.C.1
Anand, K.2
Hesdorffer, D.3
Hauser, W.A.4
French, J.A.5
-
36
-
-
0035425653
-
Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anticonvulsant drug retigabine
-
Tatulian L, Delmas P, Abogadie FC, Brown DA. Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anticonvulsant drug retigabine. J. Neurosci. 21(15), 5535-5545 (2001)
-
(2001)
J. Neurosci.
, vol.21
, Issue.15
, pp. 5535-5545
-
-
Tatulian, L.1
Delmas, P.2
Abogadie, F.C.3
Brown, D.A.4
-
37
-
-
84860595042
-
Cardiac safety and rates of sudden unexplained death in patients with partial-onset epilepsy treated with ezogabine (retigabine)
-
Brickel N, Hammond J, Viejo A, VanLandingham KE, Derossett SE. Cardiac safety and rates of sudden unexplained death in patients with partial-onset epilepsy treated with ezogabine (retigabine). Neurology 76(9), A616-A616 (2011)
-
(2011)
Neurology
, vol.76
, Issue.9
-
-
Brickel, N.1
Hammond, J.2
Viejo, A.3
VanLandingham, K.E.4
Derossett, S.E.5
-
38
-
-
76249085581
-
Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: Systematic review and meta-Analysis
-
Beyenburg S, Stavem K, Schmidt D. Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: Systematic review and meta-Analysis. Epilepsia 51(1), 7-26 (2010)
-
(2010)
Epilepsia
, vol.51
, Issue.1
, pp. 7-26
-
-
Beyenburg, S.1
Stavem, K.2
Schmidt, D.3
-
39
-
-
80054737737
-
Risk of sudden unexpected death in epilepsy in patients given adjunctive antiepileptic treatment for refractory seizures: A meta-Analysis of placebo-controlled randomised trials
-
Ryvlin P, Cucherat M, Rheims S. Risk of sudden unexpected death in epilepsy in patients given adjunctive antiepileptic treatment for refractory seizures: A meta-Analysis of placebo-controlled randomised trials. Lancet Neurol. 10(11), 961-968 (2011)
-
(2011)
Lancet Neurol.
, vol.10
, Issue.11
, pp. 961-968
-
-
Ryvlin, P.1
Cucherat, M.2
Rheims, S.3
-
40
-
-
33746145901
-
Inactivation of caspase-1 in rodent brain: A novel anticonvulsive strategy
-
Ravizza T, Lucas SM, Balosso S et al. Inactivation of caspase-1 in rodent brain: A novel anticonvulsive strategy. Epilepsia 47(7), 1160-1168 (2006)
-
(2006)
Epilepsia
, vol.47
, Issue.7
, pp. 1160-1168
-
-
Ravizza, T.1
Lucas, S.M.2
Balosso, S.3
-
41
-
-
76249084241
-
Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies
-
Wong M. Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies. Epilepsia 51(1), 27-36 (2010)
-
(2010)
Epilepsia
, vol.51
, Issue.1
, pp. 27-36
-
-
Wong, M.1
|