Zanthoxylum avicennae extracts inhibit cell proliferation through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells in vitro and in vivo

International Journal of Molecular Medicine

Volumn 29, Issue 6, 2012, Pages 1045-1052

  Dung, Tran Duc ^a,b   Chang, Hsien Cheh ^a   Binh, Truong Viet ^b   Lee, Maw Rong ^c   Tsai, Chang Hai ^d   Tsai, Fuu Jen ^a   Kuo, Wei Wen ^a   Chen, Li Mien ^e,f   Huang, Chih Yang ^a,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b Vietnam University of Traditional Pharmaco Medicine   (Viet Nam)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

^e Taichung General Hospital   (Taiwan)

^f CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Cell proliferation; Hepatocellular carcinoma; Nude mouse model; Protein phosphatase 2A; Zanthoxylum avicennae (Ying Bu Bo)

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA TUBULIN; BETA ACTIN; CELL CYCLE PROTEIN; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN E; CYCLINE; MYC PROTEIN; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PLANT EXTRACT; PROTEIN C FOS; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P21; PROTEIN P27; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZANTHOXYLUM AVICENNAE EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; FLOW CYTOMETRY; GENETIC TRANSFECTION; HERB; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROGNOSIS; TUMOR XENOGRAFT; WESTERN BLOTTING; ZANTHOXYLUM; ZANTHOXYLUM AVICENNAE;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; ENZYME ACTIVATION; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, NUDE; MODELS, BIOLOGICAL; OKADAIC ACID; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZANTHOXYLUM;

EID: 84860542258     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.938     Document Type: Article

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