Protein kinase CK2 mediates peroxynitrite-induced heme oxygenase-1 expression in articular chondrocytes

International Journal of Molecular Medicine

Volumn 29, Issue 6, 2012, Pages 1039-1044

  Kim, Kang Mi ^a   Song, Ju Dong ^a   Chung, Hun Taeg ^b   Park, Young Chul ^a  

^a Pusan National University School of Medicine   (South Korea)

^b University of Ulsan   (South Korea)

Author keywords

Chondrocytes; HO 1 expression; Nrf2; Peroxynitrite; Protein kinase CK2

Indexed keywords

4,5,6,7 TETRABROMOBENZOTRIAZOLE; BENZOTRIAZOLE DERIVATIVE; BETA ACTIN; CASEIN KINASE 2ALPHA; CASEIN KINASE II; HEME OXYGENASE 1; LINSIDOMINE; PEROXYNITRITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; BIOACCUMULATION; CARTILAGE DEGENERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INDUCTION; FEMALE; IMMUNOPRECIPITATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; APOPTOSIS; CARTILAGE, ARTICULAR; CASEIN KINASE II; CELLS, CULTURED; CHONDROCYTES; ENZYME INDUCTION; FEMALE; HEME OXYGENASE-1; MOLSIDOMINE; NF-E2-RELATED FACTOR 2; PEROXYNITROUS ACID; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84860524792     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.949     Document Type: Article

References (40)

1. Tenhunen R, Marver HS and Schmid R: The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 61: 748-755, 1968.
2. Wilks A: Heme oxygenase: evolution, structure, and mechanism. Antioxid Redox Signal 4: 603-614, 2002.
3. Wu L and Wang R: Carbon monoxide: endogenous production, physiological functions, and pharmacological application. Pharmacol Rev 57: 585-630, 2005. (Pubitemid 43036442)
4. Otterbein LE and Choi AM: Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol 279: L1029-L1037, 2000. (Pubitemid 32009488)
5. Otterbein LE, Bach FH, Alam J, Soares M, Tao LH, Wysk M, Davis RJ, Flavell RA and Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6: 422-428, 2000. (Pubitemid 30208159)
6. Duckers HJ, Boehm M, True AL, Yet SF, San H, Park JL, Clinton WR, Lee ME, Nabel GL and Nabel EG: Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med 7: 693-698, 2001. (Pubitemid 32588025)
7. Pae HO, Choi BM, Oh GS, Lee MS, Ryu DG, Rhew HY, Kim YM and Chung HT: Roles of heme oxygenase-1 in the antiproliferative and antiapoptotic effects of nitric oxide on Jurkat T cells. Mol Pharmacol 66: 122-128, 2004.
8. Henrotin YE, Bruckner P and Pujol JP: The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 11: 747-755, 2003. (Pubitemid 37184493)
9. Guillen MI, Megias J, Gomar F and Alcaraz MJ: Heme oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes. J Pathol 214: 515-522, 2008. (Pubitemid 351340572)
10. Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S and Yamamoto M: Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275: 16023-16029, 2000. (Pubitemid 30366908)
11. Zhang DD and Hannink M: Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 23: 8137-8151, 2003. (Pubitemid 37377505)
12. Kietzmann T, Samoylenko A and Immenschuh S: Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes. J Biol Chem 278: 17927-17936, 2003. (Pubitemid 36799399)
13. Li MH, Cha YN and Surh YJ: Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radic Biol Med 41: 1079-1091, 2006.
14. Litchfield DW: Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369: 1-15, 2003.
15. Meggio F and Pinna LA: One-thousand-and-one substrates of protein kinase CK2? FASEB J 17: 349-368, 2003. (Pubitemid 36292951)
16. Faust M and Montenarh M: Subcellular localization of protein kinase CK2. A key to its function? Cell Tissue Res 301: 329-340, 2000. (Pubitemid 30663550)
17. Ahmed K, Gerber DA and Cochet C: Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol 12: 226-230, 2000.
18. Pinna LA: Protein kinase CK2: a challenge to canons. J Cell Sci 115: 3873-3878, 2002.
19. Ahmad KA, Wang G, Unger G, Slaton J and Ahmed K: Protein kinase CK2 - a key suppressor of apoptosis. Adv Enzyme Regul 48: 179-187, 2008.
20. Issinger OG: Casein kinases: pleiotropic mediators of cellular regulation. Pharmacol Ther 59: 1-30, 1993.
21. Guerra B and Issinger OG: Protein kinase CK2 in human diseases. Curr Med Chem 15: 1870-1886, 2008.
22. Pi J, Bai Y and Reece JM: Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2. Free Radic Biol Med 42: 1797-1806, 2007. (Pubitemid 46754754)
23. Apopa PL, He X and Ma Q: Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells. J Biochem Mol Toxicol 22: 63-76, 2008. (Pubitemid 351360163)
24. Afonyushkin T, Oskolkova OV, Binder BR and Bochkov VN: Involvement of CK2 in activation of electrophilic genes in endothelial cells by oxidized phospholipids. J Lipid Res 52: 98-103, 2011.
25. Zwerina J, Tzima S, Hayer S, Redlich K, Hoffmann O, Hanslik-Schnabel B, Smolen JS, Kollias G and Schett G: Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption. FASEB J 19: 2011-2013, 2005. (Pubitemid 41759748)
26. Bouton C and Demple B: Nitric oxide-inducible expression of heme oxygenase-1 in human cells: translation-independent stabilization of the mRNA and evidence for direct action of nitric oxide. J Biol Chem 275: 32688-32693, 2000.
27. Durante W, Kroll MH, Christodoulides N, Peyton KJ and Schafer AI: Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ Res 80: 557-564, 1997. (Pubitemid 27137293)
28. Naughton P, Foresti R, Bains SK, Hoque M, Green CJ and Motterlini R: Induction of heme oxygenase 1 by nitrosative stress. J Biol Chem 277: 40666-40674, 2002.
29. Kurozumi R, Takahashi M and Kojima S: Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis. Biol Pharm Bull 28: 779-785, 2005. (Pubitemid 40740640)
30. Kim HJ, Tsoy I, Park MK, Lee YS, Lee JH, Seo HG and Chang KC: Iron released by sodium nitroprusside contributes to heme oxygenase-1 induction via the cAMP-protein kinase A-mitogen-activated protein kinase pathway in RAW264.7 cells. Mol Pharmacol 69: 1633-1640, 2006.
31. Niknahad H and O'Brien PJ: Involvement of nitric oxide in nitroprusside-induced hepatocyte cytotoxicity. Biochem Pharmacol 51: 1031-1039, 1996. (Pubitemid 26104625)
32. Li MH, Cha YN and Surh YJ: Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential. Biochem Biophys Res Commun 342: 984-990, 2006.
33. Lee SW, Song YS, Shin SH, Kim KT, Park YC, Park BS, Yun I, Kim K, Lee SY, Chung WT, et al: Cilostazol protects rat chondrocytes against nitric oxide-induced apoptosis in vitro and prevents cartilage destruction in a rat model of osteoarthritis. Arthritis Rheum 58: 790-800, 2008. (Pubitemid 351364877)
34. Nilakantan V, Liang H, Maenpaa CJ and Johnson CP: Differential patterns of peroxynitrite mediated apoptosis in proximal tubular epithelial cells following ATP depletion recovery. Apoptosis 13: 621-633, 2008.
35. Hara E, Takahashi K, Takeda K, Nakayama M, Yoshizawa M, Fujita H, Shirato K and Shibahara S: Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. Biochem Pharmacol 58: 227-236, 1999. (Pubitemid 29255939)
36. Szabo C, Ischiropoulos H and Radi R: Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 6: 662-680, 2007. (Pubitemid 47207751)
37. Poderoso JJ, Carreras MC, Lisdero C, Riobo N, Schopfer F and Boveris A: Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles. Arch Biochem Biophys 328: 85-92, 1996. (Pubitemid 26108173)
38. Yu R, Chen C, Mo YY, Hebbar V, Owuor ED, Tan TH and Kong AN: Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J Biol Chem 275: 39907-39913, 2000. (Pubitemid 32064611)
39. Polte T, Abate A, Dennery PA and Schröder H: Heme oxygenase-1 is a cGMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide. Arterioscler Thromb Vasc Biol 20: 1209-1215, 2000. (Pubitemid 30262920)
40. Kim HA, Lee KB and Bae SC: The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death. Arthritis Res Ther 7: R526-R535, 2005.