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Volumn 1, Issue JAN, 2011, Pages

Genetic manipulation of Francisella tularensis

Author keywords

Allelic exchange; Plasmid; Select agent; Targetron; Transposon; Tularemia

Indexed keywords


EID: 84860520595     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2010.00142     Document Type: Review
Times cited : (12)

References (73)
  • 3
    • 0028046970 scopus 로고
    • Isolation of a Francisella tularensis mutant that is sensitive to serum and oxidative killing and is avirulent in mice: correlation with the loss of MinD homologue expression
    • Anthony, L. S., Cowley, S. C., Mdluli, K. E., and Nano, F. E. (1994). Isolation of a Francisella tularensis mutant that is sensitive to serum and oxidative killing and is avirulent in mice: correlation with the loss of MinD homologue expression. FEMS Microbiol. Lett. 124, 157-165.
    • (1994) FEMS Microbiol. Lett. , vol.124 , pp. 157-165
    • Anthony, L.S.1    Cowley, S.C.2    Mdluli, K.E.3    Nano, F.E.4
  • 6
    • 33749019466 scopus 로고    scopus 로고
    • Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence
    • Bakshi, C. S., Malik, M., Regan, K., Melendez, J. A., Metzger, D. W., Pavlov, V. M., and Sellati, T. J. (2006). Superoxide dismutase B gene (sodB)-deficient mutants of Francisella tularensis demonstrate hypersensitivity to oxidative stress and attenuated virulence. J. Bacteriol. 188, 6443-6448.
    • (2006) J. Bacteriol. , vol.188 , pp. 6443-6448
    • Bakshi, C.S.1    Malik, M.2    Regan, K.3    Melendez, J.A.4    Metzger, D.W.5    Pavlov, V.M.6    Sellati, T.J.7
  • 7
    • 72049089849 scopus 로고    scopus 로고
    • The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence
    • Barker, J. R., Chong, A., Wehrly, T. D., Yu, J. J., Rodriguez, S. A., Liu, J., Celli, J., Arulanandam, B. P., and Klose, K. E. (2009). The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence. Mol. Microbiol. 74, 1459-1470.
    • (2009) Mol. Microbiol. , vol.74 , pp. 1459-1470
    • Barker, J.R.1    Chong, A.2    Wehrly, T.D.3    Yu, J.J.4    Rodriguez, S.A.5    Liu, J.6    Celli, J.7    Arulanandam, B.P.8    Klose, K.E.9
  • 8
    • 0031596298 scopus 로고    scopus 로고
    • MglA and MglB are required for the intramacrophage growth of Francisella novicida
    • Baron, G. S., and Nano, F. E. (1998). MglA and MglB are required for the intramacrophage growth of Francisella novicida. Mol. Microbiol. 29, 247-259.
    • (1998) Mol. Microbiol. , vol.29 , pp. 247-259
    • Baron, G.S.1    Nano, F.E.2
  • 9
    • 0032790677 scopus 로고    scopus 로고
    • The respiratory burst-inhibiting acid phosphatase AcpA is not essential for the intramacrophage growth or virulence of Francisella novicida
    • Baron, G. S., Reilly, T. J., and Nano, F. E. (1999). The respiratory burst-inhibiting acid phosphatase AcpA is not essential for the intramacrophage growth or virulence of Francisella novicida. FEMS Microbiol. Lett. 176, 85-90.
    • (1999) FEMS Microbiol. Lett. , vol.176 , pp. 85-90
    • Baron, G.S.1    Reilly, T.J.2    Nano, F.E.3
  • 10
    • 77956881754 scopus 로고    scopus 로고
    • Construction of a bioluminescence reporter plasmid for Francisella tularensis
    • Bina, X. R., Miller, M. A., and Bina, J. E. (2010). Construction of a bioluminescence reporter plasmid for Francisella tularensis. Plasmid 64, 156-161.
    • (2010) Plasmid , vol.64 , pp. 156-161
    • Bina, X.R.1    Miller, M.A.2    Bina, J.E.3
  • 11
    • 33747710110 scopus 로고    scopus 로고
    • The Bla2 beta-lactamase from the live-vaccine strain of Francisella tularensis encodes a functional protein that is only active against penicillin-class beta-lactam antibiotics
    • Bina, X. R., Wang, C., Miller, M. A., and Bina, J. E. (2006). The Bla2 beta-lactamase from the live-vaccine strain of Francisella tularensis encodes a functional protein that is only active against penicillin-class beta-lactam antibiotics. Arch. Microbiol. 186, 219-228.
    • (2006) Arch. Microbiol. , vol.186 , pp. 219-228
    • Bina, X.R.1    Wang, C.2    Miller, M.A.3    Bina, J.E.4
  • 12
    • 43049087013 scopus 로고    scopus 로고
    • Identification of differentially regulated Francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system
    • Buchan, B. W., McLendon, M. K., and Jones, B. D. (2008). Identification of differentially regulated Francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system. Appl. Environ. Microbiol. 74, 2637-2645.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 2637-2645
    • Buchan, B.W.1    McLendon, M.K.2    Jones, B.D.3
  • 14
    • 32044466694 scopus 로고    scopus 로고
    • Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron
    • Chen, Y., McClane, B. A., Fisher, D. J., Rood, J. I., and Gupta, P. (2005). Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron. Appl. Environ. Microbiol. 71, 7542-7547.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 7542-7547
    • Chen, Y.1    McClane, B.A.2    Fisher, D.J.3    Rood, J.I.4    Gupta, P.5
  • 15
    • 33846845100 scopus 로고    scopus 로고
    • The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth
    • doi: 10.1186/1471-2180-7-1
    • de Bruin, O. M., Ludu, J. S., and Nano, F. E. (2007). The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growth. BMC Microbiol. 7, 1. doi: 10.1186/1471-2180-7-1
    • (2007) BMC Microbiol , vol.7 , Issue.1
    • de Bruin, O.M.1    Ludu, J.S.2    Nano, F.E.3
  • 16
    • 0001130195 scopus 로고
    • Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig
    • Eigelsbach, H. T., and Downs, C. M. (1961). Prophylactic effectiveness of live and killed tularemia vaccines. I. Production of vaccine and evaluation in the white mouse and guinea pig. J. Immunol. 87, 415-425.
    • (1961) J. Immunol. , vol.87 , pp. 415-425
    • Eigelsbach, H.T.1    Downs, C.M.2
  • 17
    • 0028342649 scopus 로고
    • Streptomycin and alternative agents for the treatment of tularemia: review of the literature
    • Enderlin, G., Morales, L., Jacobs, R. F., and Cross, J. T. (1994). Streptomycin and alternative agents for the treatment of tularemia: review of the literature. Clin. Infect. Dis. 19, 42-47.
    • (1994) Clin. Infect. Dis. , vol.19 , pp. 42-47
    • Enderlin, G.1    Morales, L.2    Jacobs, R.F.3    Cross, J.T.4
  • 18
    • 0030987050 scopus 로고    scopus 로고
    • Characterization of the nucleotide sequence of the groE operon encoding heat shock proteins chaperone-60 and -10 of Francisella tularensis and determination of the T-cell response to the proteins in individuals vaccinated with F
    • Ericsson, M., Golovliov, I., Sandstrom, G., Tarnvik, A., and Sjostedt, A. (1997). Characterization of the nucleotide sequence of the groE operon encoding heat shock proteins chaperone-60 and -10 of Francisella tularensis and determination of the T-cell response to the proteins in individuals vaccinated with F. tularensis. Infect. Immun. 65, 1824-1829.
    • (1997) tularensis Infect. Immun. , vol.65 , pp. 1824-1829
    • Ericsson, M.1    Golovliov, I.2    Sandstrom, G.3    Tarnvik, A.4    Sjostedt, A.5
  • 20
    • 34748901912 scopus 로고    scopus 로고
    • Genetics and genetic manipulation in Francisella tularensis
    • Frank, D. W., and Zahrt, T. C. (2007). Genetics and genetic manipulation in Francisella tularensis. Ann. N. Y. Acad. Sci. 1105, 67-97.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1105 , pp. 67-97
    • Frank, D.W.1    Zahrt, T.C.2
  • 21
    • 0037315696 scopus 로고    scopus 로고
    • Genetic manipulation of Lactococcus lactis by using targeted group II introns: generation of stable insertions without selection
    • Frazier, C. L., San Filippo, J., Lambowitz, A. M., and Mills, D. A. (2003). Genetic manipulation of Lactococcus lactis by using targeted group II introns: generation of stable insertions without selection. Appl. Environ. Microbiol. 69, 1121-1128.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 1121-1128
    • Frazier, C.L.1    San Filippo, J.2    Lambowitz, A.M.3    Mills, D.A.4
  • 22
    • 57349123553 scopus 로고    scopus 로고
    • Genetic dissection of the Francisella novicida restriction barrier
    • Gallagher, L. A., McKevitt, M., Ramage, E. R., and Manoil, C. (2008). Genetic dissection of the Francisella novicida restriction barrier. J. Bacteriol. 190, 7830-7837.
    • (2008) J. Bacteriol. , vol.190 , pp. 7830-7837
    • Gallagher, L.A.1    McKevitt, M.2    Ramage, E.R.3    Manoil, C.4
  • 26
    • 0141446069 scopus 로고    scopus 로고
    • An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells
    • Golovliov, I., Baranov, V., Krocova, Z., Kovarova, H., and Sjostedt, A. (2003a). An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells. Infect. Immun. 71, 5940-5950.
    • (2003) Infect. Immun. , vol.71 , pp. 5940-5950
    • Golovliov, I.1    Baranov, V.2    Krocova, Z.3    Kovarova, H.4    Sjostedt, A.5
  • 29
    • 55149115099 scopus 로고    scopus 로고
    • Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis
    • doi: 10.1186/1471-2180-8-172
    • Horzempa, J., Carlson, P. E. Jr., O'Dee, D. M., Shanks, R. M., and Nau, G. J. (2008). Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis. BMC Microbiol. 8, 172. doi: 10.1186/1471-2180-8-172
    • (2008) BMC Microbiol , vol.8 , pp. 172
    • Horzempa, J.1    Carlson Jr, P.E.2    O'Dee, D.M.3    Shanks, R.M.4    Nau, G.J.5
  • 30
    • 71749093470 scopus 로고    scopus 로고
    • Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis
    • Horzempa, J., Shanks, R. M., Brown, M. J., Russo, B. C., O'Dee, D. M., and Nau, G. J. (2010). Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis. J. Microbiol. Methods 80, 106-108.
    • (2010) J. Microbiol. Methods , vol.80 , pp. 106-108
    • Horzempa, J.1    Shanks, R.M.2    Brown, M.J.3    Russo, B.C.4    O'Dee, D.M.5    Nau, G.J.6
  • 31
    • 79955917005 scopus 로고    scopus 로고
    • New vector tools with a hygromycin resistance marker for use with opportunistic pathogens
    • doi: 10.1007/s12033-010-9342-x. [Epub ahead of print]
    • Kalivoda, E. J., Horzempa, J., Stella, N. A., Sadaf, A., Kowalski, R. P., Nau, G. J., and Shanks, R. M. (2010). New vector tools with a hygromycin resistance marker for use with opportunistic pathogens. Mol. Biotechnol. doi: 10.1007/s12033-010-9342-x. [Epub ahead of print].
    • (2010) Mol. Biotechnol.
    • Kalivoda, E.J.1    Horzempa, J.2    Stella, N.A.3    Sadaf, A.4    Kowalski, R.P.5    Nau, G.J.6    Shanks, R.M.7
  • 32
    • 0035199354 scopus 로고    scopus 로고
    • Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria
    • Karberg, M., Guo, H., Zhong, J., Coon, R., Perutka, J., and Lambowitz, A. M. (2001). Group II introns as controllable gene targeting vectors for genetic manipulation of bacteria. Nat. Biotechnol. 19, 1162-1167.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 1162-1167
    • Karberg, M.1    Guo, H.2    Zhong, J.3    Coon, R.4    Perutka, J.5    Lambowitz, A.M.6
  • 33
    • 78349233071 scopus 로고    scopus 로고
    • A bacterial two-hybrid system that utilizes Gateway cloning for rapid screening of protein-protein interactions
    • Karna, S. L., Zogaj, X., Barker, J., Seshu, J., Dove, S., and Klose, K. (2010). A bacterial two-hybrid system that utilizes Gateway cloning for rapid screening of protein-protein interactions. BioTechniques 49, 831-833.
    • (2010) BioTechniques , vol.49 , pp. 831-833
    • Karna, S.L.1    Zogaj, X.2    Barker, J.3    Seshu, J.4    Dove, S.5    Klose, K.6
  • 34
    • 8744257762 scopus 로고    scopus 로고
    • Use of transposon-transposase complexes to create stable insertion mutant strains of Francisella tularensis LVS
    • Kawula, T. H., Hall, J. D., Fuller, J. R., and Craven, R. R. (2004). Use of transposon-transposase complexes to create stable insertion mutant strains of Francisella tularensis LVS. Appl. Environ. Microbiol. 70, 6901-6904.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 6901-6904
    • Kawula, T.H.1    Hall, J.D.2    Fuller, J.R.3    Craven, R.R.4
  • 35
    • 0035960731 scopus 로고    scopus 로고
    • Construction of a reporter plasmid for screening in vivo promoter activity in Francisella tularensis
    • Kuoppa, K., Forsberg, A., and Norqvist, A. (2001). Construction of a reporter plasmid for screening in vivo promoter activity in Francisella tularensis. FEMS Microbiol. Lett. 205, 77-81.
    • (2001) FEMS Microbiol. Lett. , vol.205 , pp. 77-81
    • Kuoppa, K.1    Forsberg, A.2    Norqvist, A.3
  • 37
    • 70349562476 scopus 로고    scopus 로고
    • Description of two new plasmids isolated from Francisella philomiragia strains and construction of shuttle vectors for the study of Francisella tularensis
    • Le Pihive, E., Blaha, D., Chenavas, S., Thibault, F., Vidal, D., and Valade, E. (2009). Description of two new plasmids isolated from Francisella philomiragia strains and construction of shuttle vectors for the study of Francisella tularensis. Plasmid 62, 147-157.
    • (2009) Plasmid , vol.62 , pp. 147-157
    • Le Pihive, E.1    Blaha, D.2    Chenavas, S.3    Thibault, F.4    Vidal, D.5    Valade, E.6
  • 38
    • 33847716729 scopus 로고    scopus 로고
    • The resistance of Francisella strains against reactive nitrogen and oxygen species with special reference to the role of KatG
    • Lindgren, H., Shen, H., Zingmark, C., Golovliov, I., Conlan, W., and Sjostedt, A. (2007). The resistance of Francisella strains against reactive nitrogen and oxygen species with special reference to the role of KatG. Infect. Immun. 75, 1303-1309.
    • (2007) Infect. Immun. , vol.75 , pp. 1303-1309
    • Lindgren, H.1    Shen, H.2    Zingmark, C.3    Golovliov, I.4    Conlan, W.5    Sjostedt, A.6
  • 39
    • 35649020775 scopus 로고    scopus 로고
    • Construction of targeted insertion mutations in Francisella tularensis subsp. novicida
    • Liu, J., Zogaj, X., Barker, J. R., and Klose, K. E. (2007). Construction of targeted insertion mutations in Francisella tularensis subsp. novicida. Biotechniques 43, 487-492.
    • (2007) Biotechniques , vol.43 , pp. 487-492
    • Liu, J.1    Zogaj, X.2    Barker, J.R.3    Klose, K.E.4
  • 41
    • 33750934728 scopus 로고    scopus 로고
    • Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis
    • LoVullo, E. D., Sherrill, L. A., Perez, L. L., and Pavelka, M. S., Jr. (2006). Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis. Microbiology 152, 3425-3435.
    • (2006) Microbiology , vol.152 , pp. 3425-3435
    • LoVullo, E.D.1    Sherrill, L.A.2    Perez, L.L.3    Pavelka Jr, M.S.4
  • 42
    • 35648989527 scopus 로고    scopus 로고
    • Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages
    • Maier, T. M., Casey, M. S., Becker, R. H., Dorsey, C. W., Glass, E. M., Maltsev, N., Zahrt, T. C., and Frank, D. W. (2007). Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages. Infect. Immun. 75, 5376-5389.
    • (2007) Infect. Immun. , vol.75 , pp. 5376-5389
    • Maier, T.M.1    Casey, M.S.2    Becker, R.H.3    Dorsey, C.W.4    Glass, E.M.5    Maltsev, N.6    Zahrt, T.C.7    Frank, D.W.8
  • 43
    • 10444282165 scopus 로고    scopus 로고
    • Construction and characterization of a highly efficient Francisella shuttle plasmid
    • Maier, T. M., Havig, A., Casey, M., Nano, F. E., Frank, D. W., and Zahrt, T. C. (2004). Construction and characterization of a highly efficient Francisella shuttle plasmid. Appl. Environ. Microbiol. 70, 7511-7519.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 7511-7519
    • Maier, T.M.1    Havig, A.2    Casey, M.3    Nano, F.E.4    Frank, D.W.5    Zahrt, T.C.6
  • 45
    • 75549087142 scopus 로고    scopus 로고
    • Systematic cloning of an ORFeome using the gateway system
    • Matsuyama, A., and Yoshida, M. (2009). Systematic cloning of an ORFeome using the gateway system. Methods Mol. Biol. 577, 11-24.
    • (2009) Methods Mol. Biol. , vol.577 , pp. 11-24
    • Matsuyama, A.1    Yoshida, M.2
  • 46
    • 0034425539 scopus 로고    scopus 로고
    • Bactericidal activities of antibiotics against intracellular Francisella tularensis
    • Maurin, M., Mersali, N. F., and Raoult, D. (2000). Bactericidal activities of antibiotics against intracellular Francisella tularensis. Antimicrob. Agents Chemother. 44, 3428-3431.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 3428-3431
    • Maurin, M.1    Mersali, N.F.2    Raoult, D.3
  • 47
    • 33750326392 scopus 로고    scopus 로고
    • Francisella tularensis: taxonomy, genetics, and immunopathogenesis of a potential agent of biowarfare
    • McLendon, M. K., Apicella, M. A., and Allen, L. A. (2006). Francisella tularensis: taxonomy, genetics, and immunopathogenesis of a potential agent of biowarfare. Annu. Rev. Microbiol. 60, 167-185.
    • (2006) Annu. Rev. Microbiol. , vol.60 , pp. 167-185
    • McLendon, M.K.1    Apicella, M.A.2    Allen, L.A.3
  • 48
    • 0028583128 scopus 로고
    • Serum-sensitive mutation of Francisella novicida: association with an ABC transporter gene
    • Mdluli, K. E., Anthony, L. S., Baron, G. S., McDonald, M. K., Myltseva, S. V., and Nano, F. E. (1994). Serum-sensitive mutation of Francisella novicida: association with an ABC transporter gene. Microbiology 140(PART 12), 3309-3318.
    • (1994) Microbiology , vol.140 , Issue.PART 12 , pp. 3309-3318
    • Mdluli, K.E.1    Anthony, L.S.2    Baron, G.S.3    McDonald, M.K.4    Myltseva, S.V.5    Nano, F.E.6
  • 49
    • 78049496555 scopus 로고    scopus 로고
    • Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia
    • Michell, S. L., Dean, R. E., Eyles, J. E., Hartley, M. G., Waters, E., Prior, J. L., Titball, R. W., and Oyston, P. C. (2010). Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia. J. Med. Microbiol. 59, 1275-1284.
    • (2010) J. Med. Microbiol. , vol.59 , pp. 1275-1284
    • Michell, S.L.1    Dean, R.E.2    Eyles, J.E.3    Hartley, M.G.4    Waters, E.5    Prior, J.L.6    Titball, R.W.7    Oyston, P.C.8
  • 50
    • 33846001694 scopus 로고    scopus 로고
    • AcpA is a Francisella acid phosphatase that affects intramacrophage survival and virulence
    • Mohapatra, N. P., Balagopal, A., Soni, S., Schlesinger, L. S., and Gunn, J. S. (2007). AcpA is a Francisella acid phosphatase that affects intramacrophage survival and virulence. Infect. Immun. 75, 390-396.
    • (2007) Infect. Immun. , vol.75 , pp. 390-396
    • Mohapatra, N.P.1    Balagopal, A.2    Soni, S.3    Schlesinger, L.S.4    Gunn, J.S.5
  • 51
    • 0029880276 scopus 로고    scopus 로고
    • Construction of a shuttle vector for use in Francisella tularensis
    • Norqvist, A., Kuoppa, K., and Sandstrom, G. (1996). Construction of a shuttle vector for use in Francisella tularensis. FEMS Immunol. Med. Microbiol. 13, 257-260.
    • (1996) FEMS Immunol. Med. Microbiol. , vol.13 , pp. 257-260
    • Norqvist, A.1    Kuoppa, K.2    Sandstrom, G.3
  • 52
    • 33746596554 scopus 로고    scopus 로고
    • Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain
    • Pechous, R., Celli, J., Penoske, R., Hayes, S. F., Frank, D. W., and Zahrt, T. C. (2006). Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain. Infect. Immun. 74, 4452-4461.
    • (2006) Infect. Immun. , vol.74 , pp. 4452-4461
    • Pechous, R.1    Celli, J.2    Penoske, R.3    Hayes, S.F.4    Frank, D.W.5    Zahrt, T.C.6
  • 53
    • 0742289608 scopus 로고    scopus 로고
    • Use of computer-designed group II introns to disrupt Escherichia coli DExH/Dbox protein and DNA helicase genes
    • Perutka, J., Wang, W., Goerlitz, D., and Lambowitz, A. M. (2004). Use of computer-designed group II introns to disrupt Escherichia coli DExH/Dbox protein and DNA helicase genes. J. Mol. Biol. 336, 421-439.
    • (2004) J. Mol. Biol. , vol.336 , pp. 421-439
    • Perutka, J.1    Wang, W.2    Goerlitz, D.3    Lambowitz, A.M.4
  • 55
    • 33748148231 scopus 로고    scopus 로고
    • Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2
    • doi: 10.1186/1471-2180-6-69
    • Qin, A., and Mann, B. J. (2006). Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2. BMC Microbiol. 6, 69. doi: 10.1186/1471-2180-6-69
    • (2006) BMC Microbiol , vol.6 , pp. 69
    • Qin, A.1    Mann, B.J.2
  • 56
    • 2542497869 scopus 로고    scopus 로고
    • Qin, A., Tucker, A. M., Hines, A., and Wood, D. O. (2004). Transposon mutagenesis of the obligate intracellular pathogen Rickettsia prowazekii. Appl. Environ. Microbiol. 70, 2816-2822.
    • (2004) , vol.70 , pp. 2816-2822
    • Qin, A.1    Tucker, A.M.2    Hines, A.3    Wood, D.O.4
  • 57
    • 48149110160 scopus 로고    scopus 로고
    • fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4
    • Ramakrishnan, G., Meeker, A., and Dragulev, B. (2008). fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4. J. Bacteriol. 190, 5353-5361.
    • (2008) J. Bacteriol. , vol.190 , pp. 5353-5361
    • Ramakrishnan, G.1    Meeker, A.2    Dragulev, B.3
  • 58
    • 34547755937 scopus 로고    scopus 로고
    • Development of novel plasmid vectors and a promoter trap system in Francisella tularensis compatible with the pFLN10 based plasmids
    • Rasko, D. A., Esteban, C. D., and Sperandio, V. (2007). Development of novel plasmid vectors and a promoter trap system in Francisella tularensis compatible with the pFLN10 based plasmids. Plasmid 58, 159-166.
    • (2007) Plasmid , vol.58 , pp. 159-166
    • Rasko, D.A.1    Esteban, C.D.2    Sperandio, V.3
  • 59
    • 70349759576 scopus 로고    scopus 로고
    • Targeted gene disruption in Francisella tularensis by group II introns
    • Rodriguez, S. A., Davis, G., and Klose, K. E. (2009). Targeted gene disruption in Francisella tularensis by group II introns. Methods 49, 270-274.
    • (2009) Methods , vol.49 , pp. 270-274
    • Rodriguez, S.A.1    Davis, G.2    Klose, K.E.3
  • 62
    • 77957730038 scopus 로고    scopus 로고
    • The fslE homolog, FTL_0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS
    • Sen, B., Meeker, A., and Ramakrishnan, G. (2010). The fslE homolog, FTL_0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS. Infect. Immun. 78, 4276-4285.
    • (2010) Infect. Immun. , vol.78 , pp. 4276-4285
    • Sen, B.1    Meeker, A.2    Ramakrishnan, G.3
  • 63
    • 34249868441 scopus 로고    scopus 로고
    • Genome-wide identification of Francisella tularensis virulence determinants
    • Su, J., Yang, J., Zhao, D., Kawula, T. H., Banas, J. A., and Zhang, J. R. (2007). Genome-wide identification of Francisella tularensis virulence determinants. Infect. Immun. 75, 3089-3101.
    • (2007) Infect. Immun. , vol.75 , pp. 3089-3101
    • Su, J.1    Yang, J.2    Zhao, D.3    Kawula, T.H.4    Banas, J.A.5    Zhang, J.R.6
  • 64
    • 33748028835 scopus 로고    scopus 로고
    • Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge
    • Tempel, R., Lai, X. H., Crosa, L., Kozlowicz, B., and Heffron, F. (2006). Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge. Infect. Immun. 74, 5095-5105.
    • (2006) Infect. Immun. , vol.74 , pp. 5095-5105
    • Tempel, R.1    Lai, X.H.2    Crosa, L.3    Kozlowicz, B.4    Heffron, F.5
  • 65
    • 33845979136 scopus 로고    scopus 로고
    • The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens
    • Thomas, R. M., Titball, R. W., Oyston, P. C., Griffin, K., Waters, E., Hitchen, P. G., Michell, S. L., Grice, I. D., Wilson, J. C., and Prior, J. L. (2007). The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. Infect. Immun. 75, 371-378.
    • (2007) Infect. Immun. , vol.75 , pp. 371-378
    • Thomas, R.M.1    Titball, R.W.2    Oyston, P.C.3    Griffin, K.4    Waters, E.5    Hitchen, P.G.6    Michell, S.L.7    Grice, I.D.8    Wilson, J.C.9    Prior, J.L.10
  • 67
    • 0014599499 scopus 로고
    • Transformation of Pasteurella novicida
    • Tyeryar, F. J. Jr., and Lawton, W. D. (1969). Transformation of Pasteurella novicida. J. Bacteriol. 100, 1112-1113.
    • (1969) J. Bacteriol. , vol.100 , pp. 1112-1113
    • Tyeryar Jr, F.J.1    Lawton, W.D.2
  • 68
    • 33845263419 scopus 로고
    • Factors affecting transformation of Pasteurella novicida
    • Tyeryar, F. J., and Lawton, W. D. (1970). Factors affecting transformation of Pasteurella novicida. J. Bacteriol. 104, 1312-1317.
    • (1970) J. Bacteriol. , vol.104 , pp. 1312-1317
    • Tyeryar, F.J.1    Lawton, W.D.2
  • 69
    • 44449141330 scopus 로고    scopus 로고
    • In vitro susceptibility of isolates of Francisella tularensis types A and B from North America
    • Urich, S. K., and Petersen, J. M. (2008). In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. Antimicrob. Agents Chemother. 52, 2276-2278.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2276-2278
    • Urich, S.K.1    Petersen, J.M.2
  • 72
    • 33745634120 scopus 로고    scopus 로고
    • Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll
    • Yao, J., Zhong, J., Fang, Y., Geisinger, E., Novick, R. P., and Lambowitz, A. M. (2006). Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing. RNA 12, 1271-1281.
    • (2006) LtrB group II intron splicing. RNA , vol.12 , pp. 1271-1281
    • Yao, J.1    Zhong, J.2    Fang, Y.3    Geisinger, E.4    Novick, R.P.5    Lambowitz, A.M.6
  • 73
    • 51149089097 scopus 로고    scopus 로고
    • Characterization of the Francisella tularensis subsp. novicida type IV pilus
    • Zogaj, X., Chakraborty, S., Liu, J., Thanassi, D. G., and Klose, K. E. (2008). Characterization of the Francisella tularensis subsp. novicida type IV pilus. Microbiology 154, 2139-2150.
    • (2008) Microbiology , vol.154 , pp. 2139-2150
    • Zogaj, X.1    Chakraborty, S.2    Liu, J.3    Thanassi, D.G.4    Klose, K.E.5


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