A high concentration of genistein down-regulates activin a, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells

Experimental and Molecular Medicine

Volumn 44, Issue 4, 2012, Pages 281-292

  Dixon, Darlene ^a,c   Di, Xudong ^b   Andrews, Danica M K ^b   Tucker, Charles J ^a   Yu, Linda ^a   Moore, Alicia B ^a   Zheng, Xiaolin ^a   Castro, Lysandra ^a   Hermon, Tonia ^d   Xiao, Hang ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c Bureau of Health of Wujin District   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Activin a; Genistein; Leiomyoma; Myome trium; Oligonucleotide array sequence analysis; Smad3 protein; Transforming growth factor

Indexed keywords

ACTIVIN A; GENISTEIN; MESSENGER RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

A MYB GENE; ACTIVIN A GENE; ACTIVIN B GENE; ARTICLE; CANCER CELL CULTURE; CDK6 GENE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL PROLIFERATION; COMPUTER PROGRAM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLIN B2 GENE; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; NUCLEOTIDE SEQUENCE; P15 GENE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD3 GENE; TRANSFORMING GROWTH FACTOR BETA 2 GENE; UNINDEXED SEQUENCE; UPREGULATION; UTERUS MYOMA; WESTERN BLOTTING;

EID: 84860499592     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2012.44.4.024     Document Type: Article

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