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Volumn 64, Issue 5, 2012, Pages 441-448

Therapy with methanolic extract of Pterocarpus marsupium Roxb and Ocimum sanctum Linn reverses dyslipidemia and oxidative stress in alloxan induced type I diabetic rat model

Author keywords

Alloxan; Diabetes; Herbal extract; Oxidative stress

Indexed keywords

ACID PHOSPHATASE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIOXIDANT; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CATALASE; CHOLESTEROL; CORTICOSTERONE; CREATININE; ESTROGEN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; KINO EXTRACT; LIPID; METHANOL; OCIMUM SANCTUM EXTRACT; PLANT EXTRACT; PROGESTERONE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; UREA;

EID: 84860478590     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2010.10.011     Document Type: Article
Times cited : (15)

References (45)
  • 1
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes J.W. Role of oxidative stress in development of complications in diabetes. Diabetes 1991, 40:405-412.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 2
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: a new perspective on an old paradigm
    • Baynes J.W., Thorpe S.R. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999, 48:1-9.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 3
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Beuge J.A., Aust S.V. Microsomal lipid peroxidation. Methods Enzymol 1978, 52:302-310.
    • (1978) Methods Enzymol , vol.52 , pp. 302-310
    • Beuge, J.A.1    Aust, S.V.2
  • 4
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E., Duron O., Kelly B.M. Improved method for the determination of blood glutathione. J Lab Clin Med 1963, 61:883-887.
    • (1963) J Lab Clin Med , vol.61 , pp. 883-887
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 5
    • 0033937272 scopus 로고    scopus 로고
    • Consequences of the diabetic status on the oxidant/antioxidant balance
    • Bonnefont-Rousselot D., Bastard J.P., Delattre J. Consequences of the diabetic status on the oxidant/antioxidant balance. Diabetes Metab 2000, 26:163-176.
    • (2000) Diabetes Metab , vol.26 , pp. 163-176
    • Bonnefont-Rousselot, D.1    Bastard, J.P.2    Delattre, J.3
  • 6
    • 0019490575 scopus 로고
    • Pancreatic beta cell regeneration in rat by (-)epicatchin
    • Chakarvarty B.K., Gupta S., Gambhir S.S., Gode K.D. Pancreatic beta cell regeneration in rat by (-)epicatchin. Lancet 1981, 2:759-760.
    • (1981) Lancet , vol.2 , pp. 759-760
    • Chakarvarty, B.K.1    Gupta, S.2    Gambhir, S.S.3    Gode, K.D.4
  • 7
    • 0027374618 scopus 로고
    • Possible superoxide radicalinduced alteration of vascular reactivity in aortas from streptozotocin-treated rats
    • Chang K.C., Chung S.Y., Chong W.S., Suh J.S., Kim S.H., Noh H.K., et al. Possible superoxide radicalinduced alteration of vascular reactivity in aortas from streptozotocin-treated rats. J Pharmacol Exp Ther 1993, 266(2):992-1000.
    • (1993) J Pharmacol Exp Ther , vol.266 , Issue.2 , pp. 992-1000
    • Chang, K.C.1    Chung, S.Y.2    Chong, W.S.3    Suh, J.S.4    Kim, S.H.5    Noh, H.K.6
  • 8
    • 52149089059 scopus 로고    scopus 로고
    • Effect of Indian herbal hypoglycemic agents on antioxidant capacity and trace elements content in diabetic rats
    • Chandra A., Mahdi A.A., Singh R.K., Mahdi F., Chander R. Effect of Indian herbal hypoglycemic agents on antioxidant capacity and trace elements content in diabetic rats. J Med Food 2008, 11:506-512.
    • (2008) J Med Food , vol.11 , pp. 506-512
    • Chandra, A.1    Mahdi, A.A.2    Singh, R.K.3    Mahdi, F.4    Chander, R.5
  • 9
    • 0347165048 scopus 로고
    • An improved method for the determination of free and total cholesterol using the ferric chloride reaction
    • Crawford N. An improved method for the determination of free and total cholesterol using the ferric chloride reaction. Clin Chim Acta 1959, 3(4):357-367.
    • (1959) Clin Chim Acta , vol.3 , Issue.4 , pp. 357-367
    • Crawford, N.1
  • 11
    • 64349100367 scopus 로고    scopus 로고
    • Antidiabetic activity of Clerodendron phlomoidis leaf extract in alloxan-induced diabetic rats
    • Dhanabal S.P., Mohan Marugaraja M.K., Suresh B. Antidiabetic activity of Clerodendron phlomoidis leaf extract in alloxan-induced diabetic rats. Indian J Pharm Sci 2008, 70:841-844.
    • (2008) Indian J Pharm Sci , vol.70 , pp. 841-844
    • Dhanabal, S.P.1    Mohan Marugaraja, M.K.2    Suresh, B.3
  • 12
    • 0024555292 scopus 로고
    • Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development
    • Diamond M.P., Moley K.H., Pellicer A., Vaughn W.K., DeCherney A.H. Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development. J Reprod Fert 1989, 86:1-10.
    • (1989) J Reprod Fert , vol.86 , pp. 1-10
    • Diamond, M.P.1    Moley, K.H.2    Pellicer, A.3    Vaughn, W.K.4    DeCherney, A.H.5
  • 13
    • 0033876436 scopus 로고    scopus 로고
    • Glutathione metabolism and oxidative stress in neurodegenration
    • Dringen R. Glutathione metabolism and oxidative stress in neurodegenration. Eur J Biochem 2000, 267:49-103.
    • (2000) Eur J Biochem , vol.267 , pp. 49-103
    • Dringen, R.1
  • 14
    • 33751115007 scopus 로고    scopus 로고
    • Effect of Ocimim sanctum (Tulsi) and Vitamin E on biochemical parameters and retinopathy in streptozotocin induced diabetic rats
    • Eshrat Halim M., Mukhopadhyay A.K. Effect of Ocimim sanctum (Tulsi) and Vitamin E on biochemical parameters and retinopathy in streptozotocin induced diabetic rats. Indian J Clin Biochem 2006, 21(2):181-188.
    • (2006) Indian J Clin Biochem , vol.21 , Issue.2 , pp. 181-188
    • Eshrat Halim, M.1    Mukhopadhyay, A.K.2
  • 15
    • 0014868755 scopus 로고
    • Plasma amino acid levels in diabetic keto acidosis
    • Fleig P., Marliss E., Ohman J., Cahill J.F. Plasma amino acid levels in diabetic keto acidosis. Diabetes 1970, 19:727-729.
    • (1970) Diabetes , vol.19 , pp. 727-729
    • Fleig, P.1    Marliss, E.2    Ohman, J.3    Cahill, J.F.4
  • 16
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J., Lees M., Sloane Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957, 226:497.
    • (1957) J Biol Chem , vol.226 , pp. 497
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 17
    • 48849102213 scopus 로고    scopus 로고
    • Hypoglycemic activity of Hemidesmus indicus R.Br. On streptozotocin-induced diabetic rats
    • Gayathri M., Kannabiran K. Hypoglycemic activity of Hemidesmus indicus R.Br. On streptozotocin-induced diabetic rats. Int J Diabetes Dev Countries 2008, 28(1):6-10.
    • (2008) Int J Diabetes Dev Countries , vol.28 , Issue.1 , pp. 6-10
    • Gayathri, M.1    Kannabiran, K.2
  • 18
    • 0036000246 scopus 로고    scopus 로고
    • Medicinal plants of India with anti-diabetic potential
    • Grover J.K., Yadav S., Vats V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol 2002, 81:81-100.
    • (2002) J Ethnopharmacol , vol.81 , pp. 81-100
    • Grover, J.K.1    Yadav, S.2    Vats, V.3
  • 19
    • 33751107651 scopus 로고    scopus 로고
    • Hypoglycaemic, hypolipidemic and antioxidant properties of tulsi (Ocimlam sanctum Linn) on streptozotocin induced diabetes in rats
    • Halim E., Hussain M.A., Jamil K., Rao M.A. Hypoglycaemic, hypolipidemic and antioxidant properties of tulsi (Ocimlam sanctum Linn) on streptozotocin induced diabetes in rats. Indian J Clin Biochem 2001, 16(2):190-194.
    • (2001) Indian J Clin Biochem , vol.16 , Issue.2 , pp. 190-194
    • Halim, E.1    Hussain, M.A.2    Jamil, K.3    Rao, M.A.4
  • 20
    • 0027234723 scopus 로고
    • Antihyperlipidaemic effect of flavonoids from Pterocarpus marsupium
    • Jahroni M.A.F., Ray A.B. Antihyperlipidaemic effect of flavonoids from Pterocarpus marsupium. J Nat Prod 1993, 56:984-994.
    • (1993) J Nat Prod , vol.56 , pp. 984-994
    • Jahroni, M.A.F.1    Ray, A.B.2
  • 22
    • 0025293777 scopus 로고
    • Hydrogen peroxide production during experimental protein glycation
    • Jiang Z.Y., Woollard A.C.S., Wolf S.P. Hydrogen peroxide production during experimental protein glycation. Fed Eur Biochem Soc Amst 1990, 268:69-71.
    • (1990) Fed Eur Biochem Soc Amst , vol.268 , pp. 69-71
    • Jiang, Z.Y.1    Woollard, A.C.S.2    Wolf, S.P.3
  • 23
    • 7444234317 scopus 로고    scopus 로고
    • Effects of Pterocarpus marsupium on NIDDM induced rat gastric ulceration mucosal offensive and defensive factors
    • Joshi M.C., Dorababen M., Prabha T., Kumar M.M., Goyel R.K. Effects of Pterocarpus marsupium on NIDDM induced rat gastric ulceration mucosal offensive and defensive factors. Indian J Pharmacol 2004, 36(5):296-302.
    • (2004) Indian J Pharmacol , vol.36 , Issue.5 , pp. 296-302
    • Joshi, M.C.1    Dorababen, M.2    Prabha, T.3    Kumar, M.M.4    Goyel, R.K.5
  • 24
    • 3943106879 scopus 로고    scopus 로고
    • Evaluation of hypoglycemic and antioxidant effect of Ocimum sanctum
    • Jyoti S., Sushma S., Shashi S., Anjana T. Evaluation of hypoglycemic and antioxidant effect of Ocimum sanctum. Indian J Clin Biochem 2004, 19(2):152-155.
    • (2004) Indian J Clin Biochem , vol.19 , Issue.2 , pp. 152-155
    • Jyoti, S.1    Sushma, S.2    Shashi, S.3    Anjana, T.4
  • 27
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the auto oxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S., Marklund G. Involvement of the superoxide anion radical in the auto oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974, 47:469-474.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 28
    • 0028835878 scopus 로고
    • Antidiabetic plants and their active constituents
    • Marles R.J., Farnsworth N.R. Antidiabetic plants and their active constituents. Phytomedicine 1995, 2:137-189.
    • (1995) Phytomedicine , vol.2 , pp. 137-189
    • Marles, R.J.1    Farnsworth, N.R.2
  • 29
    • 33845526601 scopus 로고    scopus 로고
    • Biochemical evaluation of antidiabetogenic properties of some commonly used Indian plants on streptozotocin induced diabetes in experimental rats
    • Narendhirakannan R.T., Subramanian S., Kandaswamy M. Biochemical evaluation of antidiabetogenic properties of some commonly used Indian plants on streptozotocin induced diabetes in experimental rats. Clin Exp Pharmacol Physiol 2006, 33:1150-1157.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 1150-1157
    • Narendhirakannan, R.T.1    Subramanian, S.2    Kandaswamy, M.3
  • 30
    • 0034907655 scopus 로고    scopus 로고
    • Effect of garlic oil on the levels of various enzyme in the serum and tissue of streptozotocin diabetic rats
    • Ohaeri O.C. Effect of garlic oil on the levels of various enzyme in the serum and tissue of streptozotocin diabetic rats. Biosci Rep 2001, 21:19-24.
    • (2001) Biosci Rep , vol.21 , pp. 19-24
    • Ohaeri, O.C.1
  • 31
    • 33845900681 scopus 로고    scopus 로고
    • Vitamin C improves basal metabolic rate and lipid profile in alloxan-induced diabetes mellitus in rats
    • Owu D.U., Antai A.B., Udofia K.H., Obembe A.O., Obasi K.O., Eteng M.U. Vitamin C improves basal metabolic rate and lipid profile in alloxan-induced diabetes mellitus in rats. J Biosci 2006, 31:575-579.
    • (2006) J Biosci , vol.31 , pp. 575-579
    • Owu, D.U.1    Antai, A.B.2    Udofia, K.H.3    Obembe, A.O.4    Obasi, K.O.5    Eteng, M.U.6
  • 32
    • 77955701783 scopus 로고    scopus 로고
    • Ocimum sanctum Linn. A reservoir plant for therapeutic applications: an overview
    • Pattanayak P., Behera P., Das D., Panda S.K. Ocimum sanctum Linn. A reservoir plant for therapeutic applications: an overview. Phcog Rev 2010, 4:95-105.
    • (2010) Phcog Rev , vol.4 , pp. 95-105
    • Pattanayak, P.1    Behera, P.2    Das, D.3    Panda, S.K.4
  • 33
    • 44649143714 scopus 로고    scopus 로고
    • High prevalence of diabetes and cardiovascular risk factors associated with urbanization in India
    • Ramachandran A., Mary S., Yamuna A., Murugesan N., Snehalatha C. High prevalence of diabetes and cardiovascular risk factors associated with urbanization in India. Diabetes Care 2008, 31:893-898.
    • (2008) Diabetes Care , vol.31 , pp. 893-898
    • Ramachandran, A.1    Mary, S.2    Yamuna, A.3    Murugesan, N.4    Snehalatha, C.5
  • 35
    • 0027475471 scopus 로고
    • Impaired antioxidant status in diabetic rat liver. Effect of vanadate
    • Saxena A.K., Srivastava P., Kale R.K., Baquer N.Z. Impaired antioxidant status in diabetic rat liver. Effect of vanadate. Biochem Pharmacol 1993, 45(3):539-542.
    • (1993) Biochem Pharmacol , vol.45 , Issue.3 , pp. 539-542
    • Saxena, A.K.1    Srivastava, P.2    Kale, R.K.3    Baquer, N.Z.4
  • 37
    • 3943106879 scopus 로고    scopus 로고
    • Evaluation of hypoglycemic and antioxidant effect of Ocimum sanctum
    • Sethi J., Sood S., Seth S., Talwar A. Evaluation of hypoglycemic and antioxidant effect of Ocimum sanctum. Indian J Clin Biochem 2004, 19(2):152-155.
    • (2004) Indian J Clin Biochem , vol.19 , Issue.2 , pp. 152-155
    • Sethi, J.1    Sood, S.2    Seth, S.3    Talwar, A.4
  • 38
    • 84860431254 scopus 로고    scopus 로고
    • Chowkamba Sanskrit Series Office, Varanasi, India
    • Sharma RK, Dash B, Samhita C. Chowkamba Sanskrit Series Office, vol. II, Varanasi, India; 1998.
    • (1998) , vol.2
    • Sharma, R.K.1    Dash, B.2    Samhita, C.3
  • 39
    • 79953277841 scopus 로고    scopus 로고
    • Diabetic amelioration by poly herbal supplement and exercise: studies on type-I diabetic rat model
    • Singh P.K., Baxi D.B., Mukherjee R., Selvaraj J., Ramachandran A.V. Diabetic amelioration by poly herbal supplement and exercise: studies on type-I diabetic rat model. J Herb Med Toxicol 2010, 4(1):217-226.
    • (2010) J Herb Med Toxicol , vol.4 , Issue.1 , pp. 217-226
    • Singh, P.K.1    Baxi, D.B.2    Mukherjee, R.3    Selvaraj, J.4    Ramachandran, A.V.5
  • 40
    • 29144485232 scopus 로고
    • Catalase-an extra ordinary enzyme
    • Sinha A. Catalase-an extra ordinary enzyme. Science 1972, 210:71-82.
    • (1972) Science , vol.210 , pp. 71-82
    • Sinha, A.1
  • 41
    • 2042472489 scopus 로고
    • (-) Epicatchin as an antidiabetic drug
    • Subramanian S.S. (-) Epicatchin as an antidiabetic drug. Ind Drug 1981, 18:259.
    • (1981) Ind Drug , vol.18 , pp. 259
    • Subramanian, S.S.1
  • 42
    • 6544295992 scopus 로고    scopus 로고
    • Modulation of glutathione and antioxidant enzymes by Ocimum sanctum and its role in protection against radiation injury
    • Uma Devi P., Ganasoundri A. Modulation of glutathione and antioxidant enzymes by Ocimum sanctum and its role in protection against radiation injury. Indian J Exp Biol 1999, 37:262-268.
    • (1999) Indian J Exp Biol , vol.37 , pp. 262-268
    • Uma Devi, P.1    Ganasoundri, A.2
  • 43
    • 0036136963 scopus 로고    scopus 로고
    • Evaluation of antihyperglaycaemic and hypoglycaemic effect of Trigonella foenum-graceum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn on normal and alloxanized diabetic rats
    • Vats V., Grover J.K., Rathi S.S. Evaluation of antihyperglaycaemic and hypoglycaemic effect of Trigonella foenum-graceum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn on normal and alloxanized diabetic rats. J Ethanopharmacol 2002, 79(1):95-100.
    • (2002) J Ethanopharmacol , vol.79 , Issue.1 , pp. 95-100
    • Vats, V.1    Grover, J.K.2    Rathi, S.S.3
  • 44
    • 0023259759 scopus 로고
    • Glucose auto-oxidation and protein modification: the potential role of autooxidative glycosylation in diabetes
    • Wolf S.P., Dean R.T. Glucose auto-oxidation and protein modification: the potential role of autooxidative glycosylation in diabetes. Biochem J 1987, 245:243-246.
    • (1987) Biochem J , vol.245 , pp. 243-246
    • Wolf, S.P.1    Dean, R.T.2
  • 45
    • 0028934334 scopus 로고
    • The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat
    • Young I.S., Tate S., Lightbody J.H., McMaster D., Trimble E.R. The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat. Free Radic Biol Med 1995, 18(5):833-840.
    • (1995) Free Radic Biol Med , vol.18 , Issue.5 , pp. 833-840
    • Young, I.S.1    Tate, S.2    Lightbody, J.H.3    McMaster, D.4    Trimble, E.R.5


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