In Vitro Antioxidant Activity Study of Novel Chromone Derivatives

Chemical Biology and Drug Design

Volumn 79, Issue 6, 2012, Pages 981-989

  Phosrithong, Narumol ^a   Samee, Weerasak ^b   Nunthanavanit, Patcharawee ^b   Ungwitayatorn, Jiraporn ^c  

^a SIAM UNIVERSITY   (Thailand)

^b SRINAKHARINWIROT UNIVERSITY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Chromone derivatives; Radical scavenging activity

Indexed keywords

CHROMONE DERIVATIVE; FISETIN; LUTEOLIN; QUERCETIN;

ANTIOXIDANT ACTIVITY; ARTICLE; DRUG STRUCTURE; IN VITRO STUDY; PRIORITY JOURNAL;

CHELATING AGENTS; CHROMONES; FERRICYANIDES; FREE RADICAL SCAVENGERS; METALS; OXIDATION-REDUCTION;

EID: 84860477134     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2012.01368.x     Document Type: Article

References (37)

1. Farber J.L. (1994) Mechanisms of cell injury by activated oxygen. Environ Health Perspect;102:17-24.
2. Pryor W.A. (1991) The antioxidant nutrient and disease prevention. Am J Clin Nutr;53:391-393.
3. Kinsella J.E., Frankel E., German B., Kanner J. (1993) Possible mechanism for the protective role of the antioxidant in wine and plant foods. Food Technol;47:85-89.
4. Lai L.S., Chou S.T., Chao W.W. (2001) Studies on the antioxidative activities of Hsiantsao (Mesonaprocumbens Hemsl) leaf gum. J Agric Food Chem;49:963-968.
5. Gülçin I., Oktay M., Kireçci E., Küfrevioǧlu O.I. (2003) Screening of antioxidant and antimicrobial activities of anise (Pimpinellaanisum L.) seed extracts. Food Chem;83:371-382.
6. Teixeira S., Siquet C., Alves C., Boal I., Marques P., Borges F., Lima J.L., Reis S. (2005) Structure-property studies on the antioxidant activity of flavonoids present in diet. Free Radic Biol Med;39:1099-1108.
7. Ji H.F., Zhang H.Y. (2006) Theoretical evaluation of flavonoids as multipotent agents to combat Alzheimer's disease. J Mol Struct;767:3-9.
8. Bors W., Saran M. (1987) Radical scavenging by flavonoid antioxidants. Free Radical Res Commun;2:289-294.
9. Havsteen B. (1983) Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol;32:1141-1148.
10. Harborne J.B., Williams C.A. (2000) Advances in flavonoid research since 1992. Phytochemistry;55:481-504.
11. Gabor M. (1986) Anti-inflammatory and anti-allergic properties of flavonoids. Prog Clin Biol Res;213:471-480.
12. Breinholt V., Hossaini A., Svendsen G.W., Brouwer C., Nielsen E. (2000) Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability. Food Chem Toxicol;38:555-564.
13. Hu C.G., Chen K., Shi Q., Kilkuskie R.E., Cheng Y.C., Lee K.H. (1994) Anti-AIDS agents, 10. Acacetin-7-O-β-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids. J Nat Prod;57:42-51.
14. Jesús O.-V., Leonardo P.-L. (2002) Structure-activity relationships for the anti-HIV activity of flavonoids. J Chem Inf Comput Sci;42:1241-1246.
15. Ren W., Qiao Z., Wang H., Zhu L., Zhang L. (2003) Flavonoids: promising anticancer agents. Med Res Rev;23:519-534.
16. Ramos S. (2007) Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention. J Nutr Biochem;18:427-442.
17. Castelluccio C., Paganga G., Melikian N., Bolwell G.P., Pridham J., Sampson J., Rice-Evans C. (1995) Antoxidant potential of intermediates in phenylpropanoid metabolism in higher plants. FEBS Lett;368:188-192.
18. Salah N., Miller N.J., Paganga G., Tijburg L., Bolwell G.P., Rice-Evans C. (1995) Polyphenolic flavonols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch Biochem Biophys;322:339-346.
19. Shahidi F., Wanasundara P.K. (1992) Phenolic antioxidants. Crit Rev Food Sci Nutr;32:67-103.
20. Afanas'ev I.B., Dorozkho A.I., Brodskii A.V., Kostyuk V.A., Potapovitsch A.I. (1989) Chelating and free radical scavenging mechanism of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem Pharmacol;38:1763-1769.
21. Dais M.M., Machado N.F.L., Marques M.P.M. (2011) Dietary chromones as antioxidants-the structural variable. Food Funct;2:595-602.
22. Ungwitayatorn J., Wiwat C., Samee W., Nunthanavanit P., Phosrithong N. (2011) Synthesis, in vitro evaluation, and docking studies of novel chromone derivatives as HIV-1 protease inhibitor. J Mol Struct;1001:152-161.
23. Soares J.R., Dinis T.C.P., Cunha A.P., Ameida L.M. (1997) Antioxidant activities of some extracts of Thymus zygis. Free Radic Res;26:469-478.
24. Dinis T.C.P., Madeira V.M.C., Almeida M.L.M. (1994) Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys;315:161-169.
25. Yamaguchi F., Ariga T., Yoshimira Y., Nakazawa H. (2000) Antioxidative and anti-glycation activity of garcinol from Garcinia indica fruit rind. J Agric Food Chem;48:180-185.
26. Kikuzaki H., Nakatani N. (1993) Antioxidants effect of water extract of Aegle marmelos fruits in streptozotocin diabetic rats. J Ethnopharmacol;87:2007-2010.
27. Ottolenghi A. (1959) Interaction of ascorbic acid and mitochondria lipids. Arch Biochem Biophys;79:355-363.
28. Gray J.I. (1978) Measurement of lipid oxidation: a review. J Am Oil Chem Soc;55:539-546.
29. Oyaizu M. (1986) Studies on products of browning reaction prepared from glucosamine. Jpn J Nutr;44:307-316.
30. Stein G.S., Baserga R., Giordano A., Denhard D.T., editors. (1999) The Molecular Basis of Cell Cycle and Growth Control, 1st edn. New York: John Wiley & Sons.
31. - radical scavenging properties of some flavonoids and related phenolic compounds. Naunyn Schmiedebergs Arch Pharmacol;308:R27.
32. Seyoum A., Asres K., Kandeel E.-F. (2006) Structure-radical scavenging activity relationships of flavonoids. Phytochemistry;67:2058-2070.
33. Fiorucci S.B., Golebiowski J., Cabrol-Bass D., Antonczak S. (2007) DFT study of quercetin activated forms involved inantiradical, antioxidant, and prooxidant biological processes. J Agric Food Chem;55:903-911.
34. Gülçin I. (2006) Antioxidant and antiradical activities of L-carnitine. Life Sci;78:803-811.
35. 2+ or ultraviolet light. J Am Oil Chem Soc;75:1717-1721.
36. Sinnhuber R.O., Yu T.C., Chang Y.T. (1958) Characterization of the red pigment formed in the 2-thiobarbituric acid determination of oxidative rancidity. Food Res;23:626-633.
37. Genestra M. (2007) Oxyl radicals, redox-sensitive signalling cascades and antioxidants. Cell Signal;19:1807-1819.