Reliable detection of subclonal single-nucleotide variants in tumour cell populations

Nature Communications

Volumn 3, Issue , 2012, Pages

  Gerstung, Moritz ^a,b   Beisel, Christian ^a   Rechsteiner, Markus ^c   Wild, Peter ^c   Schraml, Peter ^c   Moch, Holger ^c   Beerenwinkel, Niko ^a,b  

^a ETH ZURICH   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CANCER DIAGNOSIS; CELL POPULATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE FREQUENCY; GENE LOCUS; GENETIC VARIABILITY; HETEROZYGOSITY LOSS; HUMAN; KIDNEY CARCINOMA; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR CELL; ALGORITHM; CLONAL EVOLUTION; EVALUATION; GENETICS; HIGH THROUGHPUT SEQUENCING; METHODOLOGY;

PROTEIN P53; VHL PROTEIN, HUMAN; VON HIPPEL LINDAU PROTEIN;

ALGORITHMS; ALLELES; CARCINOMA, RENAL CELL; CLONAL EVOLUTION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LOSS OF HETEROZYGOSITY; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR SUPPRESSOR PROTEIN P53; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84860453712     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1814     Document Type: Article

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