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Volumn 37, Issue 3, 2012, Pages 551-554

Bigger weights may not beget bigger muscles: Evidence from acute muscle protein synthetic responses after resistance exercise

Author keywords

Adaptation; Anabolic signaling; Mitochondrial; Myofibrillar; Resistance exercise; Skeletal muscle growth; Skeletal muscle protein turnover

Indexed keywords

MUSCLE PROTEIN;

EID: 84860451722     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/H2012-022     Document Type: Article
Times cited : (67)

References (28)
  • 1
    • 0033976247 scopus 로고    scopus 로고
    • Quadriceps EMG/force relationship in knee extension and leg press
    • doi:10.1097/00005768-200002000-00030
    • Alkner, B.A., Tesch, P.A., and Berg, H.E. 2000. Quadriceps EMG/force relationship in knee extension and leg press. Med. Sci. Sports Exerc. 32(2): 459-463. doi:10.1097/00005768-200002000-00030.
    • (2000) Med. Sci. Sports Exerc. , vol.32 , Issue.2 , pp. 459-463
    • Alkner, B.A.1    Tesch, P.A.2    Berg, H.E.3
  • 2
    • 66149099346 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Progression models in resistance training for healthy adults
    • American College of Sports Medicine
    • American College of Sports Medicine. 2009. American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med. Sci. Sports Exerc. 41(3): 687-708.
    • (2009) Med. Sci. Sports Exerc. , vol.41 , Issue.3 , pp. 687-708
  • 3
    • 0030859081 scopus 로고    scopus 로고
    • An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein
    • Biolo, G., Tipton, K.D., Klein, S., and Wolfe, R.R. 1997. An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am. J. Physiol. 273(1): E122-E129.
    • (1997) Am. J. Physiol. , vol.273 , Issue.1
    • Biolo, G.1    Tipton, K.D.2    Klein, S.3    Wolfe, R.R.4
  • 4
    • 66349103681 scopus 로고    scopus 로고
    • Exercise training and protein metabolism: Influences of contraction, protein intake, and sex-based differences
    • doi:10.1152/japplphysiol.91351.2008
    • Burd, N.A., Tang, J.E., Moore, D.R., and Phillips, S.M. 2009. Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences. J. Appl. Physiol. 106(5): 1692-1701. doi:10.1152/japplphysiol.91351.2008.
    • (2009) J. Appl. Physiol. , vol.106 , Issue.5 , pp. 1692-1701
    • Burd, N.A.1    Tang, J.E.2    Moore, D.R.3    Phillips, S.M.4
  • 5
    • 77955761684 scopus 로고    scopus 로고
    • Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men
    • doi:10.1113/jphysiol.2010.192856
    • Burd, N.A., Holwerda, A.M., Selby, K.C., West, D.W., Staples, A.W., Cain, N.E., et al. 2010a. Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men. J. Physiol. 588(16): 3119-3130. doi:10.1113/jphysiol.2010.192856.
    • (2010) J. Physiol. , vol.588 , Issue.16 , pp. 3119-3130
    • Burd, N.A.1    Holwerda, A.M.2    Selby, K.C.3    West, D.W.4    Staples, A.W.5    Cain, N.E.6
  • 6
    • 77957805350 scopus 로고    scopus 로고
    • Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men
    • doi:10.1371/journal.pone.0012033
    • Burd, N.A., West, D.W., Staples, A.W., Atherton, P.J., Baker, J.M., Moore, D.R., et al. 2010b. Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men. PLoS ONE, 5(8): e12033. doi:10.1371/journal.pone.0012033.
    • (2010) PLoS ONE , vol.5 , Issue.8
    • Burd, N.A.1    West, D.W.2    Staples, A.W.3    Atherton, P.J.4    Baker, J.M.5    Moore, D.R.6
  • 7
    • 79955510770 scopus 로고    scopus 로고
    • Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men
    • doi:10.3945/jn.110.135038
    • Burd, N.A., West, D.W., Moore, D.R., Atherton, P.J., Staples, A.W., Prior, T., et al. 2011. Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men. J. Nutr. 141(4): 568-573. doi:10.3945/jn.110.135038.
    • (2011) J. Nutr. , vol.141 , Issue.4 , pp. 568-573
    • Burd, N.A.1    West, D.W.2    Moore, D.R.3    Atherton, P.J.4    Staples, A.W.5    Prior, T.6
  • 8
    • 84855902966 scopus 로고    scopus 로고
    • Muscle time under tension during resistance exercise stimulates differential muscle protein subfractional synthetic responses in men
    • Burd, N.A., Andrews, R.J., West, D.W., Little, J.P., Cochran, A.J., Hector, A.J., et al. 2012. Muscle time under tension during resistance exercise stimulates differential muscle protein subfractional synthetic responses in men. J. Physiol. 590(2): 351-362.
    • (2012) J. Physiol. , vol.590 , Issue.2 , pp. 351-362
    • Burd, N.A.1    Andrews, R.J.2    West, D.W.3    Little, J.P.4    Cochran, A.J.5    Hector, A.J.6
  • 9
    • 34548463369 scopus 로고    scopus 로고
    • Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis
    • doi:10.1152/japplphysiol.00195.2007
    • Fujita, S., Abe, T., Drummond, M.J., Cadenas, J.G., Dreyer, H.C., Sato, Y., et al. 2007. Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis. J. Appl. Physiol. 103(3): 903-910. doi:10.1152/japplphysiol.00195.2007.
    • (2007) J. Appl. Physiol. , vol.103 , Issue.3 , pp. 903-910
    • Fujita, S.1    Abe, T.2    Drummond, M.J.3    Cadenas, J.G.4    Dreyer, H.C.5    Sato, Y.6
  • 10
    • 57649232182 scopus 로고    scopus 로고
    • Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
    • doi:10.1113/jphysiol.2008.160333
    • Glover, E.I., Phillips, S.M., Oates, B.R., Tang, J.E., Tarnopolsky, M.A., Selby, A., et al. 2008. Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion. J. Physiol. 586(24): 6049-6061. doi:10.1113/jphysiol.2008.160333.
    • (2008) J. Physiol. , vol.586 , Issue.24 , pp. 6049-6061
    • Glover, E.I.1    Phillips, S.M.2    Oates, B.R.3    Tang, J.E.4    Tarnopolsky, M.A.5    Selby, A.6
  • 11
    • 34547855551 scopus 로고    scopus 로고
    • Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters
    • Hartman, J.W., Tang, J.E., Wilkinson, S.B., Tarnopolsky, M.A., Lawrence, R.L., Fullerton, A.V., and Phillips, S.M. 2007. Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am. J. Clin. Nutr. 86(2): 373-381.
    • (2007) Am. J. Clin. Nutr. , vol.86 , Issue.2 , pp. 373-381
    • Hartman, J.W.1    Tang, J.E.2    Wilkinson, S.B.3    Tarnopolsky, M.A.4    Lawrence, R.L.5    Fullerton, A.V.6    Phillips, S.M.7
  • 12
    • 2942702696 scopus 로고
    • Functional significance of cell size in spinal motoneurons
    • Henneman, E., Somjen, G., and Carpenter, D.O. 1965. Functional significance of cell size in spinal motoneurons. J. Neurophysiol. 28: 560-580.
    • (1965) J. Neurophysiol. , vol.28 , pp. 560-580
    • Henneman, E.1    Somjen, G.2    Carpenter, D.O.3
  • 13
    • 84936913259 scopus 로고
    • Relationship between repetitions and selected percentages of one repetition maximum: A comparison between untrained and trained males and females
    • Hoeger, W.W.K., Hopkins, D.R., Barrette, S.L., and Hale, D.F. 1990. Relationship between repetitions and selected percentages of one repetition maximum: A comparison between untrained and trained males and females. J. Strength Cond. Res. 4(2): 47-55.
    • (1990) J. Strength Cond. Res. , vol.4 , Issue.2 , pp. 47-55
    • Hoeger, W.W.K.1    Hopkins, D.R.2    Barrette, S.L.3    Hale, D.F.4
  • 14
    • 57349103983 scopus 로고    scopus 로고
    • Changes in muscle size and MHC composition in response to resistance exercise with heavy and light loading intensity
    • doi:10.1152/japplphysiol.90538.2008
    • Holm, L., Reitelseder, S., Pedersen, T.G., Doessing, S., Petersen, S.G., Flyvbjerg, A., et al. 2008. Changes in muscle size and MHC composition in response to resistance exercise with heavy and light loading intensity. J. Appl. Physiol. 105(5): 1454-1461. doi:10.1152/japplphysiol.90538.2008.
    • (2008) J. Appl. Physiol. , vol.105 , Issue.5 , pp. 1454-1461
    • Holm, L.1    Reitelseder, S.2    Pedersen, T.G.3    Doessing, S.4    Petersen, S.G.5    Flyvbjerg, A.6
  • 15
    • 74949140414 scopus 로고    scopus 로고
    • Contraction intensity and feeding affect collagen and myofibrillar protein synthesis rates differently in human skeletal muscle
    • doi:10.1152/ajpendo.00609.2009
    • Holm, L., van Hall, G., Rose, A.J., Miller, B.F., Doessing, S., Richter, E.A., and Kjaer, M. 2010. Contraction intensity and feeding affect collagen and myofibrillar protein synthesis rates differently in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 298(2): E257-E269. doi:10.1152/ajpendo.00609.2009.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.298 , Issue.2
    • Holm, L.1    van Hall, G.2    Rose, A.J.3    Miller, B.F.4    Doessing, S.5    Richter, E.A.6    Kjaer, M.7
  • 16
    • 58149307453 scopus 로고    scopus 로고
    • Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men
    • doi:10.1113/jphysiol.2008.164483
    • Kumar, V., Selby, A., Rankin, D., Patel, R., Atherton, P., Hildebrandt, W., et al. 2009. Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men. J. Physiol. 587(1): 211-217. doi:10.1113/jphysiol.2008.164483.
    • (2009) J. Physiol. , vol.587 , Issue.1 , pp. 211-217
    • Kumar, V.1    Selby, A.2    Rankin, D.3    Patel, R.4    Atherton, P.5    Hildebrandt, W.6
  • 17
    • 33750400410 scopus 로고    scopus 로고
    • Akt signalling through GSK-3b, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy
    • doi:10.1113/jphysiol.2006.116715
    • Léger, B., Cartoni, R., Praz, M., Lamon, S., Dériaz, O., Crettenand, A., et al. 2006. Akt signalling through GSK-3b, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy. J. Physiol. 576(3): 923-933. doi:10.1113/jphysiol.2006.116715.
    • (2006) J. Physiol. , vol.576 , Issue.3 , pp. 923-933
    • Léger, B.1    Cartoni, R.2    Praz, M.3    Lamon, S.4    Dériaz, O.5    Crettenand, A.6
  • 18
    • 60349086380 scopus 로고    scopus 로고
    • Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
    • doi:10.1113/jphysiol.2008.164087
    • Moore, D.R., Tang, J.E., Burd, N.A., Rerecich, T., Tarnopolsky, M.A., and Phillips, S.M. 2009. Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise. J. Physiol. 587(4): 897-904. doi:10.1113/jphysiol.2008.164087.
    • (2009) J. Physiol. , vol.587 , Issue.4 , pp. 897-904
    • Moore, D.R.1    Tang, J.E.2    Burd, N.A.3    Rerecich, T.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 19
    • 0030822785 scopus 로고    scopus 로고
    • Mixed muscle protein synthesis and breakdown after resistance exercise in humans
    • Phillips, S.M., Tipton, K.D., Aarsland, A., Wolf, S.E., and Wolfe, R.R. 1997. Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am. J. Physiol. 273(1): E99-E107.
    • (1997) Am. J. Physiol. , vol.273 , Issue.1
    • Phillips, S.M.1    Tipton, K.D.2    Aarsland, A.3    Wolf, S.E.4    Wolfe, R.R.5
  • 20
    • 0023792331 scopus 로고
    • Neural adaptation to resistance training
    • doi:10.1249/00005768-198810001-00009
    • Sale, D.G. 1988. Neural adaptation to resistance training. Med. Sci. Sports Exerc. 20(5 Suppl.): S135-S145. doi:10.1249/00005768-198810001-00009.
    • (1988) Med. Sci. Sports Exerc. , vol.20 , Issue.5 SUPPL.
    • Sale, D.G.1
  • 21
    • 0033923607 scopus 로고    scopus 로고
    • Effects of resistance exercise combined with moderate vascular occlusion on muscular function in humans
    • Takarada, Y., Takazawa, H., Sato, Y., Takebayashi, S., Tanaka, Y., and Ishii, N. 2000. Effects of resistance exercise combined with moderate vascular occlusion on muscular function in humans. J. Appl. Physiol. 88(6): 2097-2106.
    • (2000) J. Appl. Physiol. , vol.88 , Issue.6 , pp. 2097-2106
    • Takarada, Y.1    Takazawa, H.2    Sato, Y.3    Takebayashi, S.4    Tanaka, Y.5    Ishii, N.6
  • 22
    • 0032921840 scopus 로고    scopus 로고
    • Postexercise net protein synthesis in human muscle from orally administered amino acids
    • Tipton, K.D., Ferrando, A.A., Phillips, S.M., Doyle, D., Jr, and Wolfe, R.R. 1999. Postexercise net protein synthesis in human muscle from orally administered amino acids. Am. J. Physiol. 276(4): E628-E634.
    • (1999) Am. J. Physiol. , vol.276 , Issue.4
    • Tipton, K.D.1    Ferrando, A.A.2    Phillips, S.M.3    Doyle Jr., D.4    Wolfe, R.R.5
  • 23
    • 70449334446 scopus 로고    scopus 로고
    • Acute effects of blood flow restriction on muscle activity and endurance during fatiguing dynamic knee extensions at low load
    • doi:10.1519/JSC.0b013e3181bc1c2a
    • Wernbom, M., Jarrebring, R., Andreasson, M.A., and Augustsson, J. 2009. Acute effects of blood flow restriction on muscle activity and endurance during fatiguing dynamic knee extensions at low load. J. Strength Cond. Res. 23(8): 2389-2395. doi:10.1519/JSC.0b013e3181bc1c2a.
    • (2009) J. Strength Cond. Res. , vol.23 , Issue.8 , pp. 2389-2395
    • Wernbom, M.1    Jarrebring, R.2    Andreasson, M.A.3    Augustsson, J.4
  • 24
    • 70450210312 scopus 로고    scopus 로고
    • Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men
    • doi:10.1113/jphysiol.2009.177220
    • West, D.W., Kujbida, G.W., Moore, D.R., Atherton, P., Burd, N.A., Padzik, J.P., et al. 2009. Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men. J. Physiol. 587(21): 5239-5247. doi:10.1113/jphysiol.2009.177220.
    • (2009) J. Physiol. , vol.587 , Issue.21 , pp. 5239-5247
    • West, D.W.1    Kujbida, G.W.2    Moore, D.R.3    Atherton, P.4    Burd, N.A.5    Padzik, J.P.6
  • 25
    • 73949131768 scopus 로고    scopus 로고
    • Elevations in ostensibly anabolic hormones with resistance exercise enhance neither traininginduced muscle hypertrophy nor strength of the elbow flexors
    • doi:10.1152/japplphysiol.01147.2009
    • West, D.W., Burd, N.A., Tang, J.E., Moore, D.R., Staples, A.W., Holwerda, A.M., et al. 2010. Elevations in ostensibly anabolic hormones with resistance exercise enhance neither traininginduced muscle hypertrophy nor strength of the elbow flexors. J. Appl. Physiol. 108(1): 60-67. doi:10.1152/japplphysiol.01147.2009.
    • (2010) J. Appl. Physiol. , vol.108 , Issue.1 , pp. 60-67
    • West, D.W.1    Burd, N.A.2    Tang, J.E.3    Moore, D.R.4    Staples, A.W.5    Holwerda, A.M.6
  • 26
    • 34147094595 scopus 로고    scopus 로고
    • Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage
    • Wilkinson, S.B., Tarnopolsky, M.A., Macdonald, M.J., Macdonald, J.R., Armstrong, D., and Phillips, S.M. 2007. Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am. J. Clin. Nutr. 85(4): 1031-1040.
    • (2007) Am. J. Clin. Nutr. , vol.85 , Issue.4 , pp. 1031-1040
    • Wilkinson, S.B.1    Tarnopolsky, M.A.2    Macdonald, M.J.3    Macdonald, J.R.4    Armstrong, D.5    Phillips, S.M.6
  • 27
    • 33750093325 scopus 로고    scopus 로고
    • The underappreciated role of muscle in health and disease
    • Wolfe, R.R. 2006. The underappreciated role of muscle in health and disease. Am. J. Clin. Nutr. 84(3): 475-482.
    • (2006) Am. J. Clin. Nutr. , vol.84 , Issue.3 , pp. 475-482
    • Wolfe, R.R.1
  • 28
    • 24044552980 scopus 로고    scopus 로고
    • Sex-based differences in skeletal muscle function and morphology with short-term limb immobilization
    • doi:10.1152/japplphysiol.00247.2005
    • Yasuda, N., Glover, E.I., Phillips, S.M., Isfort, R.J., and Tarnopolsky, M.A. 2005. Sex-based differences in skeletal muscle function and morphology with short-term limb immobilization. J. Appl. Physiol. 99(3): 1085-1092. doi:10.1152/japplphysiol.00247.2005.
    • (2005) J. Appl. Physiol. , vol.99 , Issue.3 , pp. 1085-1092
    • Yasuda, N.1    Glover, E.I.2    Phillips, S.M.3    Isfort, R.J.4    Tarnopolsky, M.A.5


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