The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Renga, Barbara ^a   Francisci, Daniela ^a   D'Amore, Claudio ^a   Schiaroli, Elisabetta ^a   Mencarelli, Andrea ^a   Cipriani, Sabrina ^a   Baldelli, Franco ^a   Fiorucci, Stefano ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CELL NUCLEUS RECEPTOR; FARNESOID X RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; JANUS KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PEPTIDE VACCINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P17; RECEPTOR FOR ACTIVATED C KINASE 1; RECOMBINANT PROTEIN; STAT1 PROTEIN; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; CD14 ANTIGEN; CELL RECEPTOR; CELL SURFACE RECEPTOR; DRUG DERIVATIVE; FARNESOID X-ACTIVATED RECEPTOR; FLUDARABINE; GAG PROTEIN; GNB2L1 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; ISOXAZOLE DERIVATIVE; JANUS KINASE; P17 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; ROSIGLITAZONE; STAT1 PROTEIN, HUMAN; TUMOR PROTEIN; VIDARABINE;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; LIPID METABOLISM; MACROPHAGE; MONOCYTE; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VACCINATION; ATHEROSCLEROSIS; CELL LINE; CELL SEPARATION; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; SERODIAGNOSIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGENS, CD14; ATHEROSCLEROSIS; CELL LINE; CELL SEPARATION; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HIV ANTIGENS; HIV INFECTIONS; HIV-1; HUMANS; INFLAMMATION; ISOXAZOLES; JANUS KINASES; LIPID METABOLISM; MACROPHAGES; MONOCYTES; NEOPLASM PROTEINS; NEUTRALIZATION TESTS; PHENOTYPE; PHOSPHORYLATION; PPAR GAMMA; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; THIAZOLIDINEDIONES; VACCINATION; VIDARABINE;

EID: 84860431568     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035924     Document Type: Article

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