Identification and quantification of potential metabolites of Gd-based contrast agents by electrochemistry/separations/mass spectrometry

Journal of Chromatography A

Volumn 1240, Issue , 2012, Pages 147-155

  Telgmann, Lena ^a   Faber, Helene ^a   Jahn, Sandra ^a   Melles, Daniel ^a   Simon, Hannah ^a   Sperling, Michael ^a   Karst, Uwe ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

CE ESI MS; CE ICP MS; Contrast agent; Drug metabolism; Electrochemistry; Gadolinium; Gd DTPA; LC ESI MS; LC ICP MS; MRI; NSF

Indexed keywords

CONTRAST AGENT; DRUG METABOLISMS; GD-DTPA; LC/ESI-MS; LC/ICP-MS; NSF;

BIOMOLECULES; CAPILLARY ELECTROPHORESIS; DIALYSIS; ELECTROCHEMICAL OXIDATION; ELECTROCHEMISTRY; EXPERIMENTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDUCTIVELY COUPLED PLASMA; LINEAR TRANSFORMATIONS; MAGNETIC RESONANCE IMAGING; MASS SPECTROMETRY; METABOLISM; METABOLITES;

GADOLINIUM;

CONTRAST MEDIUM; GADOLINIUM; GADOLINIUM PENTETATE;

ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEALKYLATION; ELECTROCHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATION; POTENTIOMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIMULATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONTRAST MEDIA; ELECTROCHEMICAL TECHNIQUES; GADOLINIUM; HUMANS; MALE; MICROSOMES, LIVER; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84860426353     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.03.088     Document Type: Article

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