Comprehensive profiling of the complex dendrimeric contrast agent Gadomer using a combinded approach of CE, MS, and CE-MS

Electrophoresis

Volumn 28, Issue 17, 2007, Pages 3088-3099

  Vetterlein, Kai ^a,b   Bergmann, Ulf ^c   Büche, Karlo ^a   Walker, Martina ^a   Lehmann, Jochen ^b   Linscheid, Michael W ^c   Scriba, Gerhard K E ^b   Hildebrand, Michael ^a,b  

^a BAYER PHARMA AG   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

CE MS; Dendrimers; Fourier transform ion resonance MS; Gadomer; MALDI TOF MS

Indexed keywords

DENDRIMERS; DRUG PRODUCTS; INDUCTIVELY COUPLED PLASMA; MASS SPECTROMETERS; MASS SPECTROMETRY; PRODUCT DESIGN;

ANALYTES; ANALYTICAL CHALLENGE; CE-MS; CONTRAST AGENT; FOURIER TRANSFORM-ION RESONANCE-MS; GADOMER; ION RESONANCE; ISOTOPIC PATTERN; MALDI TOF MS; SPECTROMETRIC TECHNIQUES;

CAPILLARY ELECTROPHORESIS;

CONTRAST MEDIUM; DENDRIMER; GADOLINIUM; GADOMER; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CAPILLARY ELECTROPHORESIS; CHEMICAL ANALYSIS; DRUG IMPURITY; DRUG QUALITY; DRUG SAFETY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; PROCESS OPTIMIZATION; QUALITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY;

EID: 34548745881     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200700075     Document Type: Article

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