Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1821, Issue 3, 2012, Pages 456-463

  Lyssenko, Nicholas N ^a   Hata, Mami ^b   Dhanasekaran, Padmaja ^a   Nickel, Margaret ^a   Nguyen, David ^a   Chetty, Palaniappan Sevugan ^a   Saito, Hiroyuki ^b   Lund Katz, Sissel ^a   Phillips, Michael C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Amphipathic helix; Apolipoprotein A I; ATP binding cassette transporter A1 (ABCA1); Cellular cholesterol efflux; High density lipoprotein (HDL); Lipid solubilization

Indexed keywords

APOLIPOPROTEIN A1; AROMATIC AMINO ACID; HIGH DENSITY LIPOPROTEIN;

ALPHA HELIX; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHOBICITY; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN STABILITY;

AMINO ACID SUBSTITUTION; AMINO ACIDS, AROMATIC; ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHOLESTEROL; CRICETINAE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOPROTEINS, HDL; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TRANSITION TEMPERATURE;

EID: 84860419984     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.07.020     Document Type: Article

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